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The map label for this gene is trx2 [H]

Identifier: 193212528

GI number: 193212528

Start: 950632

End: 950961

Strand: Direct

Name: trx2 [H]

Synonym: Cpar_0868

Alternate gene names: 193212528

Gene position: 950632-950961 (Clockwise)

Preceding gene: 193212527

Following gene: 193212529

Centisome position: 41.53

GC content: 51.21

Gene sequence:

>330_bases
ATGAGCGGAAAATATTTTGTGGCTACTGATCAGAATTTCCAGTCTGATATCATCAACTCTGATAAAGTGGCTCTCGTTGA
TTTCTGGGCTTCCTGGTGTGGCCCGTGCATGATGCTCGGCCCGGTTATCGAAGAGCTTGCCGGTGATTACGAAGGCAAGG
CCGTCATCGCCAAACTCAACGTCGATGAGAACCCCAACACGGCAGCACAGTTCGGTATTCGCAGCATTCCTACCATGCTG
ATCTTCAAAGGCGGACAGGTTGTTGACCAGATGGTCGGCGCTCTTCCCAAGAACATGATCGCAAAGAAGATCGACGAGTA
CCTCGCCTGA

Upstream 100 bases:

>100_bases
GAATTTCAGCACTTGTTGCCAAGTTCTGATTTATTCAGTTATATTGGCATAGAGTAACAGTGTTTCTCTTATCAATTGTT
AACCCTTATCGTTAGATCTT

Downstream 100 bases:

>100_bases
TTTTCCTTCCGTTTTTTTCTTCAACTATCCCGGCTTCATGCCGGGATAGTTATATCTAAGCATACCCCAACACATCTTCC
CGGAGATCAACGATGGATAA

Product: thioredoxin

Products: NA

Alternate protein names: Trx-2 [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSGKYFVATDQNFQSDIINSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAVIAKLNVDENPNTAAQFGIRSIPTML
IFKGGQVVDQMVGALPKNMIAKKIDEYLA

Sequences:

>Translated_109_residues
MSGKYFVATDQNFQSDIINSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAVIAKLNVDENPNTAAQFGIRSIPTML
IFKGGQVVDQMVGALPKNMIAKKIDEYLA
>Mature_108_residues
SGKYFVATDQNFQSDIINSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAVIAKLNVDENPNTAAQFGIRSIPTMLI
FKGGQVVDQMVGALPKNMIAKKIDEYLA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=82, Percent_Identity=41.4634146341463, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082331, Length=109, Percent_Identity=49.5412844036697, Blast_Score=125, Evalue=6e-31,
Organism=Escherichia coli, GI1788936, Length=106, Percent_Identity=39.622641509434, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI87081747, Length=81, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212646193, Length=99, Percent_Identity=36.3636363636364, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17510299, Length=107, Percent_Identity=37.3831775700935, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507705, Length=91, Percent_Identity=32.967032967033, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71998175, Length=96, Percent_Identity=38.5416666666667, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71980562, Length=102, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509965, Length=67, Percent_Identity=43.2835820895522, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71980565, Length=91, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321648, Length=85, Percent_Identity=42.3529411764706, Blast_Score=80, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323072, Length=79, Percent_Identity=44.3037974683544, Blast_Score=75, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319925, Length=85, Percent_Identity=35.2941176470588, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664269, Length=96, Percent_Identity=39.5833333333333, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573567, Length=87, Percent_Identity=37.9310344827586, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24639826, Length=81, Percent_Identity=40.7407407407407, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17648013, Length=80, Percent_Identity=37.5, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583090, Length=80, Percent_Identity=37.5, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17530795, Length=85, Percent_Identity=34.1176470588235, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24658597, Length=100, Percent_Identity=33, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639068, Length=103, Percent_Identity=33.9805825242718, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21358065, Length=89, Percent_Identity=32.5842696629214, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921434, Length=74, Percent_Identity=35.1351351351351, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11905; Mature: 11774

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKYFVATDQNFQSDIINSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAVIAKLN
CCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
VDENPNTAAQFGIRSIPTMLIFKGGQVVDQMVGALPKNMIAKKIDEYLA
CCCCCCHHHHHHHHHCCHHEEECCCHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SGKYFVATDQNFQSDIINSDKVALVDFWASWCGPCMMLGPVIEELAGDYEGKAVIAKLN
CCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
VDENPNTAAQFGIRSIPTMLIFKGGQVVDQMVGALPKNMIAKKIDEYLA
CCCCCCHHHHHHHHHCCHHEEECCCHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]