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The map label for this gene is hflX [H]

Identifier: 193212441

GI number: 193212441

Start: 841460

End: 842812

Strand: Direct

Name: hflX [H]

Synonym: Cpar_0778

Alternate gene names: 193212441

Gene position: 841460-842812 (Clockwise)

Preceding gene: 193212438

Following gene: 193212442

Centisome position: 36.76

GC content: 59.2

Gene sequence:

>1353_bases
GTGAATTACTATTACGAGAAGATCCATTTGATACCCATTCCATCCGCTGAACCGAGAGAGCGTGCTGTACTTGTCGGCAT
TACCTCCTCGCCCGATATTCCGAGACATCTTGTCGAAGAGTACCTCGACGAACTGGCTTTTCTTGCCGATACGGCGGGAG
CCGACGTCGTCAGTACCATCATTCAGGAAAAGAAGCAGCTCGATACAGCCACCTGTATCGGCAGCGGCAAAGCTGAAGAA
CTGGCCGCGCTGGTCGAGACGGAGTCGATCGACATCGTCATTTTCGACGACGACCTCACGCCGGTGCAGGTGCGCAACCT
CGAACGCATCCTCAAGTGCAAGGTGATCGACCGAACGGGTCTCATCCTGCAAATATTTGCCCTCCGAGCCAAATCCGCGC
AGGCCCGCACGCAGGTGGAGCTGGCGCAGCTTGAATATCTCCTGCCACGGCTTTCCGGCGCGTGGACGCACCTCTCAAAG
CAGAAGGGCGGCATCGGCACCAAAGGTCCTGGCGAAACGCAGATCGAGACCGACCGGCGACTGGTGCGCAATCGCATCGC
TTCGCTCAAAAAGAAACTCCGCGCCGTCTCGCTTCAGCACGACACCCAGACCCGTGGTCGCACCACCGTGCCGCGCGTGG
CGCTGGTAGGCTACACCAACGCGGGCAAATCGACGCTCATGAACGCGCTCTGCCCGGAAGCGGAGGCCTACGCCGAGAAC
CGCCTGTTCGCGACGCTCGACACCAAAACCCGGCGGCTCGAACTCAGGATCAACAAGCTCGTGCTGCTCTCCGACACGGT
CGGCTTCATCCGCAAGCTGCCGCATACGCTGGTCGAGAGTTTCAAATCCACGCTTGACGAGGTGTTGCAGGCCGACTTTC
TCCTGCACGTCATCGACGTGAGCCATCCGGCTTTCGAGGAGCACATGCAGGTGGTGCGCGAGACGCTCAAGGAGATCGGA
GTCAAGCACGACCACATCATCGAGGTGTTCAACAAGATCGACGCGCTCGAAGACCCGGCGGTGCTGACCGGCCTGCGCGG
CAAGTATCCCGACGCGGTGTTCATCTCCGCCGCGCGCGGACTGAACCTCACGGTGCTGAAGGAAACTATCGCCAACTACG
TCGCCCGCGACTACAAGCAGCGCAAGGTGCGCACGCACGTCTCGAACTACAAGCTGATCGGCTACCTCTACGACCACGCC
GAGGTGATCGACAAAAAGCACGTCGATGAGGATGTGCTGCTCACCATCCGCGTGCACCGCAACAACCTCAAACAGATCGA
CGCCATGCTCAAGGCGTCCGCATTGAAAAACCATGCCGCTGCAAATTTTCAACACCACGAAACGCACGATTGA

Upstream 100 bases:

>100_bases
GGAATACGTTGTCATAACGTGACGGCAAAATAACCTAAAGGCTTTAATATAGCAAGAGCGCAGGAGGTGTCCGTCTTCGC
ATGGTGCGAGCCTCCGTAGT

Downstream 100 bases:

>100_bases
CGAAGCGCTCCTCGCCGAAGCCATCCAACTGGTGATCGGCGAAGAGGGTGGCAAGGTCGGTTCCATCGAAGCTATCTACT
GCGGCAATAAAATGATCCGT

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNYYYEKIHLIPIPSAEPRERAVLVGITSSPDIPRHLVEEYLDELAFLADTAGADVVSTIIQEKKQLDTATCIGSGKAEE
LAALVETESIDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFALRAKSAQARTQVELAQLEYLLPRLSGAWTHLSK
QKGGIGTKGPGETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRTTVPRVALVGYTNAGKSTLMNALCPEAEAYAEN
RLFATLDTKTRRLELRINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPAFEEHMQVVRETLKEIG
VKHDHIIEVFNKIDALEDPAVLTGLRGKYPDAVFISAARGLNLTVLKETIANYVARDYKQRKVRTHVSNYKLIGYLYDHA
EVIDKKHVDEDVLLTIRVHRNNLKQIDAMLKASALKNHAAANFQHHETHD

Sequences:

>Translated_450_residues
MNYYYEKIHLIPIPSAEPRERAVLVGITSSPDIPRHLVEEYLDELAFLADTAGADVVSTIIQEKKQLDTATCIGSGKAEE
LAALVETESIDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFALRAKSAQARTQVELAQLEYLLPRLSGAWTHLSK
QKGGIGTKGPGETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRTTVPRVALVGYTNAGKSTLMNALCPEAEAYAEN
RLFATLDTKTRRLELRINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPAFEEHMQVVRETLKEIG
VKHDHIIEVFNKIDALEDPAVLTGLRGKYPDAVFISAARGLNLTVLKETIANYVARDYKQRKVRTHVSNYKLIGYLYDHA
EVIDKKHVDEDVLLTIRVHRNNLKQIDAMLKASALKNHAAANFQHHETHD
>Mature_450_residues
MNYYYEKIHLIPIPSAEPRERAVLVGITSSPDIPRHLVEEYLDELAFLADTAGADVVSTIIQEKKQLDTATCIGSGKAEE
LAALVETESIDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFALRAKSAQARTQVELAQLEYLLPRLSGAWTHLSK
QKGGIGTKGPGETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRTTVPRVALVGYTNAGKSTLMNALCPEAEAYAEN
RLFATLDTKTRRLELRINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPAFEEHMQVVRETLKEIG
VKHDHIIEVFNKIDALEDPAVLTGLRGKYPDAVFISAARGLNLTVLKETIANYVARDYKQRKVRTHVSNYKLIGYLYDHA
EVIDKKHVDEDVLLTIRVHRNNLKQIDAMLKASALKNHAAANFQHHETHD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=269, Percent_Identity=33.8289962825279, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI310133118, Length=265, Percent_Identity=33.9622641509434, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI310124269, Length=261, Percent_Identity=34.0996168582375, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI310124267, Length=261, Percent_Identity=34.0996168582375, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI310124171, Length=261, Percent_Identity=34.0996168582375, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI310124169, Length=261, Percent_Identity=34.0996168582375, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1790615, Length=405, Percent_Identity=42.962962962963, Blast_Score=288, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17561038, Length=325, Percent_Identity=30.1538461538462, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24650079, Length=359, Percent_Identity=31.4763231197772, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50628; Mature: 50628

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYYYEKIHLIPIPSAEPRERAVLVGITSSPDIPRHLVEEYLDELAFLADTAGADVVSTI
CCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQEKKQLDTATCIGSGKAEELAALVETESIDIVIFDDDLTPVQVRNLERILKCKVIDRTG
HHHHHHCCHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
LILQIFALRAKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKGPGETQIETDRR
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHH
LVRNRIASLKKKLRAVSLQHDTQTRGRTTVPRVALVGYTNAGKSTLMNALCPEAEAYAEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCC
RLFATLDTKTRRLELRINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDV
CEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHPAFEEHMQVVRETLKEIGVKHDHIIEVFNKIDALEDPAVLTGLRGKYPDAVFISAARG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCC
LNLTVLKETIANYVARDYKQRKVRTHVSNYKLIGYLYDHAEVIDKKHVDEDVLLTIRVHR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEECC
NNLKQIDAMLKASALKNHAAANFQHHETHD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNYYYEKIHLIPIPSAEPRERAVLVGITSSPDIPRHLVEEYLDELAFLADTAGADVVSTI
CCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQEKKQLDTATCIGSGKAEELAALVETESIDIVIFDDDLTPVQVRNLERILKCKVIDRTG
HHHHHHCCHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
LILQIFALRAKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKGPGETQIETDRR
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHH
LVRNRIASLKKKLRAVSLQHDTQTRGRTTVPRVALVGYTNAGKSTLMNALCPEAEAYAEN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCC
RLFATLDTKTRRLELRINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDV
CEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHPAFEEHMQVVRETLKEIGVKHDHIIEVFNKIDALEDPAVLTGLRGKYPDAVFISAARG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECCCC
LNLTVLKETIANYVARDYKQRKVRTHVSNYKLIGYLYDHAEVIDKKHVDEDVLLTIRVHR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEECC
NNLKQIDAMLKASALKNHAAANFQHHETHD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]