Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 193212432

GI number: 193212432

Start: 828122

End: 830518

Strand: Direct

Name: zraS [C]

Synonym: Cpar_0768

Alternate gene names: 193212432

Gene position: 828122-830518 (Clockwise)

Preceding gene: 193212429

Following gene: 193212438

Centisome position: 36.17

GC content: 46.93

Gene sequence:

>2397_bases
ATGGTGGAGGGCAAAAGTATGACGGATATGTTGCCCCAGTCGATGTACCTCATTGATGCTGAAGGGCATATGGTTAGATG
GAGCCCTTTGTTTCGTGATCGGATTGCTGGTCTTTCTGATCAATCGATGGAGTCTATCAATTTTATTGATCTGATTCATC
CTGAAGACCGAGAACTGGTGCGGCAGCGAATGCGCAATATCCTGAATCGGGGTGTGGAAGAAAGTGTTGAGGTCAGGGTG
CTCTTCAAGGGAGGGCCAACATACCGGTGGTTTGTTCTTATGGCCAACCGTTACGAGTGCGATGGAGCCGTTTTCATCAC
CGGTACTGGCGTCGATATAACGAGACTCAAAAAAGCGGAAAAGGCTTTGATGGTGAGCGAGCAGCGTTTTCGCTCAATTT
TAGAGCAGGCTGATTATCCTGTGTTTATTGCTGATATAGAAGGTTTGATCAAATACGTTTCGCCTGCATTTGAAGAGGTT
TCCGGCTATGCTTCATCAGAATGTCTCAACAGATCGTTCACGAAATTTTTTGAAGAGACTGATGGGGGGAATTCTGGTGT
GATGTTGATGCTTGATGATGTGATTTCCAATTCTGAGGATATACGAAAGTGTGAATGTACAATGCGCAAAAGGGATGGGT
CGGTATTTCCTGTTGAGATCAGACTGCATAAGTATAGTGATCATCGTGTTGAGGGTGCCATTGGGGTCTTATACGATTTG
ACTCAGCGCAAACGGTTCGATCTATTGACTGAATTTCGTTTCGATCTGCTCAGACGCGCTGAAGATGCCTCGATCGAGGA
GATTTTGCAAGGGGCGCTCGACGAGGCAGAGCAGCTTACTGACAGTTCGCTTGGGTTCATTTACTTTCTCTCTGATGATT
CAAATGGTTTGCCGAAGTATATTTGGTCGACCAAGGTTCGCGATGAGATGAGTGCCATGGGCGGCAATGGAGAACATCCG
TCATTCAATTCCATGCCCTTTCTTAAGGAGGCCATTGAGAAACGCCGTGCAATTATCGTCAATGAGCCATCTCTTTCCCT
CGATTTAGAGTTTTCTTCTTTTCAGCCAGATGTTAAAAATCGCCTTGTCGTGCCTGTTATCGATGGAGGGGAGGTGGTGG
CCGTGTGCCTGGTTGGTAACAAACCGTTTCCATACGTTGATAATGACGCCCAGTGGGTGAGTACTCTGGCTAATATGGTT
TGGGATATCGTTACCCGAAAAATGAACGAGCAGTCTGAGAATCGGATTCAGTCTATTTTGTTGCAGATTCAGAAAATGGA
GTTGATCGGTCAGCTTGCTGGTGGTATAGCTCACGATTTTAACAATATGCTCGGTGTCATTATGGGTAATACCGAGTTGG
CGATGTGCAACGATGGTCTGGATCCTTCCGTTGAAGAGAATCTTGCCGAGATTTATCGGGCGGCGGAGCGTTCAGCCGAG
ATGACCAGTCAATTGTTGGCGTTTGCCCGCAAGCAGACTGCCGTGCCCAGTGTTTTTGAGGTCGATCAGGCGATTGGAGA
TTCTCTTGCCATTTTGCAGAGAGTGGTTGGTAAGAAGATCGGGTTTGATTGGCATCCGTCAGGCGCCGGGTGCAAGGTGC
GTGTCGACCCGTCACAGTTCGACCAGATTCTCATGAATCTTTGTCTGAATGCAAGTGATGCTATGGGCGGTGAGGGAACT
ATCGTCATTAAGGCTAAACGGTTAAAAGTCGATCATACTCTGGAACATCCGGGAGGGATAAGAGAGCCCGGTGAGTATGT
TCAGATTTCGGTTAGTGACTCCGGACAGGGAATTCCCGAAGAGCACCAGTTGCATATTTTCGAGCCATTTTTTACTACGA
AAGTTCTCGGTAAGGGAACCGGTCTGGGGCTTTCTTCGATCTATGGTATCGTCAAACAGAATCGGGGATTTGTTGATTTT
GAGAGCGAGAAGGGGAATGGGACAACTTTCCATATCTACCTGCCTCTCTACAGAGAAAAAACAAACGGGTTAGGGATTGA
CAGGCAGAACTCTTCAAGTCCATCGAATCATACCACTATTCTCGTGGTTGAAGACGAACCTGAGATTCTCAGTCTTTGTA
AGATGATGCTTCAAAAGTCCGGTTTTACGGTATTAACTGCAGCATTTCCTAAAGATGCGATCATGATTGCTGAAGAGTTC
AGTGGCAAGATTGATCTGCTGTTGACCGATGTCATTATGCCGGAAATGAATGGTGTCGAGCTTGCCTCGAAACTTTCGAC
GATCAGCCCCGGCTTCAGGGTTCTCTTTATGTCGGGTTATTCGGCAGATATTATCGCGGACAAGGGTATGCCGCACAATT
CGTTCAATCTGCTCCGCAAACCTTTTACCATCAAGACGTTGATCGAAAAGGTGAACGCTGTTCTTGAGGCAAAGTGA

Upstream 100 bases:

>100_bases
TTAGTCTTTTCCATAACCAGTATTCTCAAAAAATCCTCTTTTCATGCAAGAAAATCGCACAAGCGGATCTCATGGATTGG
CAGATCATGAGGTTTCCGGT

Downstream 100 bases:

>100_bases
GATTTTATGCCTGCTCAGGTGTTGTGCTGGCGTATCTCGCCAGGGGTCAGTTCAAGCGCGCTGACTCGGACTGAAACGCT
CATCTTTTCCGATGAGGCGC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 798; Mature: 798

Protein sequence:

>798_residues
MVEGKSMTDMLPQSMYLIDAEGHMVRWSPLFRDRIAGLSDQSMESINFIDLIHPEDRELVRQRMRNILNRGVEESVEVRV
LFKGGPTYRWFVLMANRYECDGAVFITGTGVDITRLKKAEKALMVSEQRFRSILEQADYPVFIADIEGLIKYVSPAFEEV
SGYASSECLNRSFTKFFEETDGGNSGVMLMLDDVISNSEDIRKCECTMRKRDGSVFPVEIRLHKYSDHRVEGAIGVLYDL
TQRKRFDLLTEFRFDLLRRAEDASIEEILQGALDEAEQLTDSSLGFIYFLSDDSNGLPKYIWSTKVRDEMSAMGGNGEHP
SFNSMPFLKEAIEKRRAIIVNEPSLSLDLEFSSFQPDVKNRLVVPVIDGGEVVAVCLVGNKPFPYVDNDAQWVSTLANMV
WDIVTRKMNEQSENRIQSILLQIQKMELIGQLAGGIAHDFNNMLGVIMGNTELAMCNDGLDPSVEENLAEIYRAAERSAE
MTSQLLAFARKQTAVPSVFEVDQAIGDSLAILQRVVGKKIGFDWHPSGAGCKVRVDPSQFDQILMNLCLNASDAMGGEGT
IVIKAKRLKVDHTLEHPGGIREPGEYVQISVSDSGQGIPEEHQLHIFEPFFTTKVLGKGTGLGLSSIYGIVKQNRGFVDF
ESEKGNGTTFHIYLPLYREKTNGLGIDRQNSSSPSNHTTILVVEDEPEILSLCKMMLQKSGFTVLTAAFPKDAIMIAEEF
SGKIDLLLTDVIMPEMNGVELASKLSTISPGFRVLFMSGYSADIIADKGMPHNSFNLLRKPFTIKTLIEKVNAVLEAK

Sequences:

>Translated_798_residues
MVEGKSMTDMLPQSMYLIDAEGHMVRWSPLFRDRIAGLSDQSMESINFIDLIHPEDRELVRQRMRNILNRGVEESVEVRV
LFKGGPTYRWFVLMANRYECDGAVFITGTGVDITRLKKAEKALMVSEQRFRSILEQADYPVFIADIEGLIKYVSPAFEEV
SGYASSECLNRSFTKFFEETDGGNSGVMLMLDDVISNSEDIRKCECTMRKRDGSVFPVEIRLHKYSDHRVEGAIGVLYDL
TQRKRFDLLTEFRFDLLRRAEDASIEEILQGALDEAEQLTDSSLGFIYFLSDDSNGLPKYIWSTKVRDEMSAMGGNGEHP
SFNSMPFLKEAIEKRRAIIVNEPSLSLDLEFSSFQPDVKNRLVVPVIDGGEVVAVCLVGNKPFPYVDNDAQWVSTLANMV
WDIVTRKMNEQSENRIQSILLQIQKMELIGQLAGGIAHDFNNMLGVIMGNTELAMCNDGLDPSVEENLAEIYRAAERSAE
MTSQLLAFARKQTAVPSVFEVDQAIGDSLAILQRVVGKKIGFDWHPSGAGCKVRVDPSQFDQILMNLCLNASDAMGGEGT
IVIKAKRLKVDHTLEHPGGIREPGEYVQISVSDSGQGIPEEHQLHIFEPFFTTKVLGKGTGLGLSSIYGIVKQNRGFVDF
ESEKGNGTTFHIYLPLYREKTNGLGIDRQNSSSPSNHTTILVVEDEPEILSLCKMMLQKSGFTVLTAAFPKDAIMIAEEF
SGKIDLLLTDVIMPEMNGVELASKLSTISPGFRVLFMSGYSADIIADKGMPHNSFNLLRKPFTIKTLIEKVNAVLEAK
>Mature_798_residues
MVEGKSMTDMLPQSMYLIDAEGHMVRWSPLFRDRIAGLSDQSMESINFIDLIHPEDRELVRQRMRNILNRGVEESVEVRV
LFKGGPTYRWFVLMANRYECDGAVFITGTGVDITRLKKAEKALMVSEQRFRSILEQADYPVFIADIEGLIKYVSPAFEEV
SGYASSECLNRSFTKFFEETDGGNSGVMLMLDDVISNSEDIRKCECTMRKRDGSVFPVEIRLHKYSDHRVEGAIGVLYDL
TQRKRFDLLTEFRFDLLRRAEDASIEEILQGALDEAEQLTDSSLGFIYFLSDDSNGLPKYIWSTKVRDEMSAMGGNGEHP
SFNSMPFLKEAIEKRRAIIVNEPSLSLDLEFSSFQPDVKNRLVVPVIDGGEVVAVCLVGNKPFPYVDNDAQWVSTLANMV
WDIVTRKMNEQSENRIQSILLQIQKMELIGQLAGGIAHDFNNMLGVIMGNTELAMCNDGLDPSVEENLAEIYRAAERSAE
MTSQLLAFARKQTAVPSVFEVDQAIGDSLAILQRVVGKKIGFDWHPSGAGCKVRVDPSQFDQILMNLCLNASDAMGGEGT
IVIKAKRLKVDHTLEHPGGIREPGEYVQISVSDSGQGIPEEHQLHIFEPFFTTKVLGKGTGLGLSSIYGIVKQNRGFVDF
ESEKGNGTTFHIYLPLYREKTNGLGIDRQNSSSPSNHTTILVVEDEPEILSLCKMMLQKSGFTVLTAAFPKDAIMIAEEF
SGKIDLLLTDVIMPEMNGVELASKLSTISPGFRVLFMSGYSADIIADKGMPHNSFNLLRKPFTIKTLIEKVNAVLEAK

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=26.5560165975104, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=30.6034482758621, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=28.3524904214559, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI48994928, Length=265, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=305, Percent_Identity=24.5901639344262, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=27.9527559055118, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89109; Mature: 89109

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEGKSMTDMLPQSMYLIDAEGHMVRWSPLFRDRIAGLSDQSMESINFIDLIHPEDRELV
CCCCCCHHHHCCCCEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
RQRMRNILNRGVEESVEVRVLFKGGPTYRWFVLMANRYECDGAVFITGTGVDITRLKKAE
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHH
KALMVSEQRFRSILEQADYPVFIADIEGLIKYVSPAFEEVSGYASSECLNRSFTKFFEET
HHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DGGNSGVMLMLDDVISNSEDIRKCECTMRKRDGSVFPVEIRLHKYSDHRVEGAIGVLYDL
CCCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
TQRKRFDLLTEFRFDLLRRAEDASIEEILQGALDEAEQLTDSSLGFIYFLSDDSNGLPKY
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
IWSTKVRDEMSAMGGNGEHPSFNSMPFLKEAIEKRRAIIVNEPSLSLDLEFSSFQPDVKN
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCC
RLVVPVIDGGEVVAVCLVGNKPFPYVDNDAQWVSTLANMVWDIVTRKMNEQSENRIQSIL
CEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LQIQKMELIGQLAGGIAHDFNNMLGVIMGNTELAMCNDGLDPSVEENLAEIYRAAERSAE
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
MTSQLLAFARKQTAVPSVFEVDQAIGDSLAILQRVVGKKIGFDWHPSGAGCKVRVDPSQF
HHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHH
DQILMNLCLNASDAMGGEGTIVIKAKRLKVDHTLEHPGGIREPGEYVQISVSDSGQGIPE
HHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCC
EHQLHIFEPFFTTKVLGKGTGLGLSSIYGIVKQNRGFVDFESEKGNGTTFHIYLPLYREK
CCCEEEECCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEECC
TNGLGIDRQNSSSPSNHTTILVVEDEPEILSLCKMMLQKSGFTVLTAAFPKDAIMIAEEF
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHC
SGKIDLLLTDVIMPEMNGVELASKLSTISPGFRVLFMSGYSADIIADKGMPHNSFNLLRK
CCCEEEEEEHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCHHHHCC
PFTIKTLIEKVNAVLEAK
CCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVEGKSMTDMLPQSMYLIDAEGHMVRWSPLFRDRIAGLSDQSMESINFIDLIHPEDRELV
CCCCCCHHHHCCCCEEEEECCCCEEEECHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
RQRMRNILNRGVEESVEVRVLFKGGPTYRWFVLMANRYECDGAVFITGTGVDITRLKKAE
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHH
KALMVSEQRFRSILEQADYPVFIADIEGLIKYVSPAFEEVSGYASSECLNRSFTKFFEET
HHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DGGNSGVMLMLDDVISNSEDIRKCECTMRKRDGSVFPVEIRLHKYSDHRVEGAIGVLYDL
CCCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHH
TQRKRFDLLTEFRFDLLRRAEDASIEEILQGALDEAEQLTDSSLGFIYFLSDDSNGLPKY
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHH
IWSTKVRDEMSAMGGNGEHPSFNSMPFLKEAIEKRRAIIVNEPSLSLDLEFSSFQPDVKN
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCC
RLVVPVIDGGEVVAVCLVGNKPFPYVDNDAQWVSTLANMVWDIVTRKMNEQSENRIQSIL
CEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LQIQKMELIGQLAGGIAHDFNNMLGVIMGNTELAMCNDGLDPSVEENLAEIYRAAERSAE
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
MTSQLLAFARKQTAVPSVFEVDQAIGDSLAILQRVVGKKIGFDWHPSGAGCKVRVDPSQF
HHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHH
DQILMNLCLNASDAMGGEGTIVIKAKRLKVDHTLEHPGGIREPGEYVQISVSDSGQGIPE
HHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCC
EHQLHIFEPFFTTKVLGKGTGLGLSSIYGIVKQNRGFVDFESEKGNGTTFHIYLPLYREK
CCCEEEECCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEECC
TNGLGIDRQNSSSPSNHTTILVVEDEPEILSLCKMMLQKSGFTVLTAAFPKDAIMIAEEF
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHC
SGKIDLLLTDVIMPEMNGVELASKLSTISPGFRVLFMSGYSADIIADKGMPHNSFNLLRK
CCCEEEEEEHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCHHHHCC
PFTIKTLIEKVNAVLEAK
CCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA