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The map label for this gene is ald [H]

Identifier: 193212344

GI number: 193212344

Start: 723253

End: 724356

Strand: Direct

Name: ald [H]

Synonym: Cpar_0677

Alternate gene names: 193212344

Gene position: 723253-724356 (Clockwise)

Preceding gene: 193212342

Following gene: 193212348

Centisome position: 31.59

GC content: 62.32

Gene sequence:

>1104_bases
ATGAATATAGGAATTCCACGAGAGATCAAGACCCTTGAGTCGAGGGTCGCCTGCACGCCTGCGGGTGTTCGTTCGCTTGT
CGGCGCTGGCCACCGGGTGCTGGTCGAGTGCGGTGCTGGCGAGGCGAGCGGCTTCAGCGACGACAAGTACCGGCTTGCCG
GTGCGGTGCTTGTCCAGCAGCCGGAAGAGGCCTGGAGCGCCGATCTGATCGTCAAGGTCAAGGAACCGCTGGAGGAAGAG
TTCCGGTTTTTCAGGAAAGAGCAGATTCTGTTCACTTTCCTGCATCTGGCTGGCGTTCCCGGATTGGCCAAAGCGCTTGC
TGCTGCGGGCGTGACGGCGATCGGCTACGAAACTGTCGAGGTCGGCGGACGGTTGCCGCTGCTGGCTCCGATGAGCGAGA
TTGCCGGCAAGATGAGCGTGCTGATGGGCGGCTACTATCTCTCGAAGCATCACGGTGGCATGGGGAAGCTGCTCGGCGGC
GTGCCCGGCGTGCTCCCCGGCAGGGTGCTGGTGCTTGGCGGGGGAACTGCCGGGCTGAACGCCGCCCGCGCAGCAGCTGG
TCTCGGGGCTGAAGTGACCGTCATGGAGGCCGATCAGGAGCGGATGCGCACGCTTGAATCGGTGTTGCCCTCCCAGGTGC
ATACGATCTACTCGAACGAGCAGCATCTCGAAGAACTGCTGCCTGAAACCGACCTGCTCATTGGCGCGGTGCTGCTTGCC
GGAGCCAGTGCTCCGAAGCTCGTTACCCGGCAGATGGTTCAGGCGATGAAGCCTGGCGCTGTGCTGGTCGATATTGCCAT
TGATCAGGGAGGATGCATCGAGACATCGCGCCCGACCACCCATCACGATCCGGTGTTTGTGGAAGAGGGCGCAGTGCACT
ACTGCGTCACCAACATGCCAGCGGCCTATCCCGCAACCTCGACCGAAGCGCTGACCGGCGTGACGCTGCCTTACGTCAGG
AGGCTCGCCGACCTGGGACTTGAAAGCGCGATGGTGGTGATGCCTGGGCTTGCCGGTGGGCTGAATGTGTGGGATGGCAA
AATTGTGCAGCCTGCCGTGGCCGCATCGCTTGGCGTCGAGTGTGGAAAGAATCCTTTTGTGTGA

Upstream 100 bases:

>100_bases
TCTCGGAGCCCATTGCCATACGTTTTTTCTGTGATATTCCGGAAATGGAAGCCGGAGTACTACATTGTTACGAAGAGGAA
AACTCTGATCATTTTCAGCC

Downstream 100 bases:

>100_bases
AATAGCGATAAGTGTAGGGGCATCCCGACTTGTCGGGATGCCCACAAGTAACGTCGCTAAATTTTGTAGATCAGTTTCGT
TGTTTTCTCAAGGCACCAGC

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNIGIPREIKTLESRVACTPAGVRSLVGAGHRVLVECGAGEASGFSDDKYRLAGAVLVQQPEEAWSADLIVKVKEPLEEE
FRFFRKEQILFTFLHLAGVPGLAKALAAAGVTAIGYETVEVGGRLPLLAPMSEIAGKMSVLMGGYYLSKHHGGMGKLLGG
VPGVLPGRVLVLGGGTAGLNAARAAAGLGAEVTVMEADQERMRTLESVLPSQVHTIYSNEQHLEELLPETDLLIGAVLLA
GASAPKLVTRQMVQAMKPGAVLVDIAIDQGGCIETSRPTTHHDPVFVEEGAVHYCVTNMPAAYPATSTEALTGVTLPYVR
RLADLGLESAMVVMPGLAGGLNVWDGKIVQPAVAASLGVECGKNPFV

Sequences:

>Translated_367_residues
MNIGIPREIKTLESRVACTPAGVRSLVGAGHRVLVECGAGEASGFSDDKYRLAGAVLVQQPEEAWSADLIVKVKEPLEEE
FRFFRKEQILFTFLHLAGVPGLAKALAAAGVTAIGYETVEVGGRLPLLAPMSEIAGKMSVLMGGYYLSKHHGGMGKLLGG
VPGVLPGRVLVLGGGTAGLNAARAAAGLGAEVTVMEADQERMRTLESVLPSQVHTIYSNEQHLEELLPETDLLIGAVLLA
GASAPKLVTRQMVQAMKPGAVLVDIAIDQGGCIETSRPTTHHDPVFVEEGAVHYCVTNMPAAYPATSTEALTGVTLPYVR
RLADLGLESAMVVMPGLAGGLNVWDGKIVQPAVAASLGVECGKNPFV
>Mature_367_residues
MNIGIPREIKTLESRVACTPAGVRSLVGAGHRVLVECGAGEASGFSDDKYRLAGAVLVQQPEEAWSADLIVKVKEPLEEE
FRFFRKEQILFTFLHLAGVPGLAKALAAAGVTAIGYETVEVGGRLPLLAPMSEIAGKMSVLMGGYYLSKHHGGMGKLLGG
VPGVLPGRVLVLGGGTAGLNAARAAAGLGAEVTVMEADQERMRTLESVLPSQVHTIYSNEQHLEELLPETDLLIGAVLLA
GASAPKLVTRQMVQAMKPGAVLVDIAIDQGGCIETSRPTTHHDPVFVEEGAVHYCVTNMPAAYPATSTEALTGVTLPYVR
RLADLGLESAMVVMPGLAGGLNVWDGKIVQPAVAASLGVECGKNPFV

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=330, Percent_Identity=31.8181818181818, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI122939153, Length=330, Percent_Identity=31.8181818181818, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1787887, Length=346, Percent_Identity=32.0809248554913, Blast_Score=144, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17550456, Length=333, Percent_Identity=30.6306306306306, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38389; Mature: 38389

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIPREIKTLESRVACTPAGVRSLVGAGHRVLVECGAGEASGFSDDKYRLAGAVLVQQ
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHEEEC
PEEAWSADLIVKVKEPLEEEFRFFRKEQILFTFLHLAGVPGLAKALAAAGVTAIGYETVE
CHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCEEEE
VGGRLPLLAPMSEIAGKMSVLMGGYYLSKHHGGMGKLLGGVPGVLPGRVLVLGGGTAGLN
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCCCCCEEEEEECCCCCCH
AARAAAGLGAEVTVMEADQERMRTLESVLPSQVHTIYSNEQHLEELLPETDLLIGAVLLA
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
GASAPKLVTRQMVQAMKPGAVLVDIAIDQGGCIETSRPTTHHDPVFVEEGAVHYCVTNMP
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
AAYPATSTEALTGVTLPYVRRLADLGLESAMVVMPGLAGGLNVWDGKIVQPAVAASLGVE
CCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCC
CGKNPFV
CCCCCCC
>Mature Secondary Structure
MNIGIPREIKTLESRVACTPAGVRSLVGAGHRVLVECGAGEASGFSDDKYRLAGAVLVQQ
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHEEEC
PEEAWSADLIVKVKEPLEEEFRFFRKEQILFTFLHLAGVPGLAKALAAAGVTAIGYETVE
CHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCEEEE
VGGRLPLLAPMSEIAGKMSVLMGGYYLSKHHGGMGKLLGGVPGVLPGRVLVLGGGTAGLN
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCCCCCEEEEEECCCCCCH
AARAAAGLGAEVTVMEADQERMRTLESVLPSQVHTIYSNEQHLEELLPETDLLIGAVLLA
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
GASAPKLVTRQMVQAMKPGAVLVDIAIDQGGCIETSRPTTHHDPVFVEEGAVHYCVTNMP
CCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
AAYPATSTEALTGVTLPYVRRLADLGLESAMVVMPGLAGGLNVWDGKIVQPAVAASLGVE
CCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCC
CGKNPFV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]