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The map label for this gene is trpG [H]

Identifier: 193212064

GI number: 193212064

Start: 421239

End: 421802

Strand: Direct

Name: trpG [H]

Synonym: Cpar_0394

Alternate gene names: 193212064

Gene position: 421239-421802 (Clockwise)

Preceding gene: 193212063

Following gene: 193212065

Centisome position: 18.4

GC content: 55.85

Gene sequence:

>564_bases
ATGATTCTTGTTATAGATAATTACGACTCGTTTACGTACAACCTTGTTCAGTACATCGGCGAACTTGGTGCTGAGGTGGT
GGTGTACCGGAACGATGAACTCACCGTCGAACAGGCGCTGGCGCTCAAGCCGGAGAAGATTGTTATTTCGCCTGGTCCCG
GCACGCCTGCCGATGCGGGAATTTCCATTCCGCTCATCAACGCCGTGAAAGGCAAGATTCCGCTCTTCGGCGTCTGCCTC
GGCCATCAGGCCATCGGCGAAGCGCTTGGCGGCAAGGTGGTTCGCGCTGGACAGATCATGCACGGCAAGACCTCGGAGGT
CTATCACAACAACAAAGGCGTGTTCCGCGGCCTTCCCAATCCCTTTATCGCTACCCGCTACCACTCGCTCGTTGTGGAGC
GCGAAAGCCTGCCTGCCGAGCTTGAAATCACCGCTTGGACCGAGGACGAGGTCATCATGGGCCTTCAGTCCAGCGAACTC
GGGTTGCATGGCGTGCAGTTCCATCCCGAATCGATCATGACCTCTGTCGGCCACGATCTCATCAAAAATTTCTTGGACAT
CTGA

Upstream 100 bases:

>100_bases
TGCGCCTTGAAGTCCGCCAGCGGCTCTCATGAGGCTCCGAGGCGGGCGTCATCCGTAAGAATTTTTTAAGTCTTTATTCA
ATAGTGTTTTACGTGCTCTC

Downstream 100 bases:

>100_bases
TTTGTCATGGGAGAGCCAAAGAAACGCAAACCGGAGTGGGCTGTCAGGGCTGCTGAAACCCCCGTGCCGCAAGCGCCGCT
GCTTGCCGGAAGCGAGTTCA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILVIDNYDSFTYNLVQYIGELGAEVVVYRNDELTVEQALALKPEKIVISPGPGTPADAGISIPLINAVKGKIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSEVYHNNKGVFRGLPNPFIATRYHSLVVERESLPAELEITAWTEDEVIMGLQSSEL
GLHGVQFHPESIMTSVGHDLIKNFLDI

Sequences:

>Translated_187_residues
MILVIDNYDSFTYNLVQYIGELGAEVVVYRNDELTVEQALALKPEKIVISPGPGTPADAGISIPLINAVKGKIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSEVYHNNKGVFRGLPNPFIATRYHSLVVERESLPAELEITAWTEDEVIMGLQSSEL
GLHGVQFHPESIMTSVGHDLIKNFLDI
>Mature_187_residues
MILVIDNYDSFTYNLVQYIGELGAEVVVYRNDELTVEQALALKPEKIVISPGPGTPADAGISIPLINAVKGKIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSEVYHNNKGVFRGLPNPFIATRYHSLVVERESLPAELEITAWTEDEVIMGLQSSEL
GLHGVQFHPESIMTSVGHDLIKNFLDI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=173, Percent_Identity=30.0578034682081, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=62.1621621621622, Blast_Score=247, Evalue=3e-67,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=42.7807486631016, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786215, Length=177, Percent_Identity=29.9435028248588, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=25.2631578947368, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=49.1978609625668, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=36.9668246445498, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20331; Mature: 20331

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTYNLVQYIGELGAEVVVYRNDELTVEQALALKPEKIVISPGPGTPADAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISIPLINAVKGKIPLFGVCLGHQAIGEALGGKVVRAGQIMHGKTSEVYHNNKGVFRGLPN
CEEEEECCCCCCCCEEEEECCHHHHHHHHCCCEEECCEEECCCCHHEEECCCCEECCCCC
PFIATRYHSLVVERESLPAELEITAWTEDEVIMGLQSSELGLHGVQFHPESIMTSVGHDL
CHHHHHHHHHEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHH
IKNFLDI
HHHHHCC
>Mature Secondary Structure
MILVIDNYDSFTYNLVQYIGELGAEVVVYRNDELTVEQALALKPEKIVISPGPGTPADAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISIPLINAVKGKIPLFGVCLGHQAIGEALGGKVVRAGQIMHGKTSEVYHNNKGVFRGLPN
CEEEEECCCCCCCCEEEEECCHHHHHHHHCCCEEECCEEECCCCHHEEECCCCEECCCCC
PFIATRYHSLVVERESLPAELEITAWTEDEVIMGLQSSELGLHGVQFHPESIMTSVGHDL
CHHHHHHHHHEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHH
IKNFLDI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]