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The map label for this gene is 193212060

Identifier: 193212060

GI number: 193212060

Start: 416596

End: 417096

Strand: Direct

Name: 193212060

Synonym: Cpar_0390

Alternate gene names: NA

Gene position: 416596-417096 (Clockwise)

Preceding gene: 193212057

Following gene: 193212061

Centisome position: 18.2

GC content: 59.28

Gene sequence:

>501_bases
ATGCCGTTAAGGTTTCTTTTTGTCTGTTACGAGAACATCTGCCGCTCACCGATGGCAGAGGGCGTTTTCGGGCATCTGGC
CGAATCGATGGGCGCGGGTTCGTTTTTCGAGGTCGAGTCGGCGGGCACGGTTTGTTACCAGTCCGGCTCGTGTCCCGACG
AGCGGGCCATTCGCGCTGCCGGTCGGCACGGGATCGATATTTCATCGATCCGGGCGCGCTGTATTCACGATCTCGATCTG
GCGCGCTTCGACCGGATTTTTGCGATGGATTTCGAGAACCATCGCGACCTGTACGATGCGCTGGAAGGCCGTCCGGTTTC
GGTGCACATGATGACCGAGTTCGCCGGTTCGGATGCGGGCGAGGAGATCGAAGACCCCTACTATGGCGACGAGGCGGGGT
TCGACCGGACGCTTCGGCGTCTCATGGAGAGCGCCACAGGCATTCTTGAAGCCATGCTTGTCGAATACGGTTTTCCGGAT
GATGGAGGCCATGAGCGGTAA

Upstream 100 bases:

>100_bases
TACTATAAAAGAAAGTATTCGCTATGATTCTTTTTGTTTTACCTCAGCGAGTTGCGCCATTGATGCAGAGGGAAAGGCGC
GTTTATCATTGTGAAAAGCT

Downstream 100 bases:

>100_bases
CGTCACCTTTATTTTTAATCCCGCCGCCGACAAGGGACGCGCGGCTGCGAAGGCGGAAATGGTCAGGCGTTCGCTTGCGC
AGTTCGATCACTGTACGCTT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MPLRFLFVCYENICRSPMAEGVFGHLAESMGAGSFFEVESAGTVCYQSGSCPDERAIRAAGRHGIDISSIRARCIHDLDL
ARFDRIFAMDFENHRDLYDALEGRPVSVHMMTEFAGSDAGEEIEDPYYGDEAGFDRTLRRLMESATGILEAMLVEYGFPD
DGGHER

Sequences:

>Translated_166_residues
MPLRFLFVCYENICRSPMAEGVFGHLAESMGAGSFFEVESAGTVCYQSGSCPDERAIRAAGRHGIDISSIRARCIHDLDL
ARFDRIFAMDFENHRDLYDALEGRPVSVHMMTEFAGSDAGEEIEDPYYGDEAGFDRTLRRLMESATGILEAMLVEYGFPD
DGGHER
>Mature_165_residues
PLRFLFVCYENICRSPMAEGVFGHLAESMGAGSFFEVESAGTVCYQSGSCPDERAIRAAGRHGIDISSIRARCIHDLDLA
RFDRIFAMDFENHRDLYDALEGRPVSVHMMTEFAGSDAGEEIEDPYYGDEAGFDRTLRRLMESATGILEAMLVEYGFPDD
GGHER

Specific function: Unknown

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=148, Percent_Identity=38.5135135135135, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI6005988, Length=148, Percent_Identity=35.1351351351351, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325330, Length=151, Percent_Identity=30.4635761589404, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI78706770, Length=137, Percent_Identity=38.6861313868613, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706772, Length=137, Percent_Identity=38.6861313868613, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=32.0261437908497, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78706764, Length=129, Percent_Identity=35.6589147286822, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI78706766, Length=129, Percent_Identity=35.6589147286822, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI78706768, Length=129, Percent_Identity=35.6589147286822, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18519; Mature: 18388

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRFLFVCYENICRSPMAEGVFGHLAESMGAGSFFEVESAGTVCYQSGSCPDERAIRAA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCHHHHHHHH
GRHGIDISSIRARCIHDLDLARFDRIFAMDFENHRDLYDALEGRPVSVHMMTEFAGSDAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHHHCCCCC
EEIEDPYYGDEAGFDRTLRRLMESATGILEAMLVEYGFPDDGGHER
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PLRFLFVCYENICRSPMAEGVFGHLAESMGAGSFFEVESAGTVCYQSGSCPDERAIRAA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCHHHHHHHH
GRHGIDISSIRARCIHDLDLARFDRIFAMDFENHRDLYDALEGRPVSVHMMTEFAGSDAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHHHCCCCC
EEIEDPYYGDEAGFDRTLRRLMESATGILEAMLVEYGFPDDGGHER
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]