Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 193212024

GI number: 193212024

Start: 377244

End: 377993

Strand: Direct

Name: dapB

Synonym: Cpar_0353

Alternate gene names: 193212024

Gene position: 377244-377993 (Clockwise)

Preceding gene: 193212023

Following gene: 193212025

Centisome position: 16.48

GC content: 60.13

Gene sequence:

>750_bases
ATGAAGGTTACCCTGGTCGGCAATGGCCGTATGGGCCAGCAGATCGCCGGTATCGTCAACGCATCGGACGCCAATGTTAT
CCACAAGGTGCTCGATGTGAGCGACGCCGTTACGCCGGAAGTGTTCGAGGGATCGGATGCGATTATCGATTTCACCGTCA
GGGATGCGTTCCTGGCGAACTACAAGGCGATGATTGCCTCCGGCGTGCCGGTTGTGGTTGGCACCACCGGCTGGGACGAG
TTGATGCCGCAGATCGCCGAAGAGGTGAATGCCGCCGGAAGCTCGATGCTCTACTCGGCCAACTTTTCGCTTGGCGTGAA
CGTCTTCTTCCGGACATTGCGTGAGGCGGCTCGCCTGATCGCTCCGTTCGAGCAGTTCGACATCGCGCTCTCCGAACAGC
ACCATACCGGCAAGGCGGATTTCCCGAGCGGCACAGCGATCAAGGCAGCGCAGGAGGTTCTGAATAACAATCCGCGGAAG
CGCACCATCGTTCGTGAGCTTGAGGACGGCAAGAAGTTGCAGAGCGACGAATTGCAGGTCTCGTCGATCCGTCTCGGCAC
GGTGTTCGGCGTGCACTCGGCTATTATCGATTCCGAGTCGGACACCATCGAGCTGACCCACACGGCCAAGAACCGCACCG
GCTTCGCTTCGGGCGCCGTTCGCGCCGCCGAATGGCTCGCCCAGCAGCACGCCGCAAAGCCGGGCTTCTACACGATGGAC
GATTTCCTGAACGATCTCTTTTCGGCCTGA

Upstream 100 bases:

>100_bases
AAATACTTCTCCGGCGAGGATCTCGACAGGATTCTCGACCTGCTCGGTCAGTGAGCGTTCCGGAGGAGTCATTTCCTGAA
ATTCCAAGTAGTATGAGATT

Downstream 100 bases:

>100_bases
AGGATGGGTATAGACGTTATTCCGGCCCGTCCATCGAAAAACACGGCGATCGCGCTTGGCGCGGCGTTGCTGTTGCTGAC
GACCACGGTGCCCTACCTGA

Product: Dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKVTLVGNGRMGQQIAGIVNASDANVIHKVLDVSDAVTPEVFEGSDAIIDFTVRDAFLANYKAMIASGVPVVVGTTGWDE
LMPQIAEEVNAAGSSMLYSANFSLGVNVFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAAQEVLNNNPRK
RTIVRELEDGKKLQSDELQVSSIRLGTVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLAQQHAAKPGFYTMD
DFLNDLFSA

Sequences:

>Translated_249_residues
MKVTLVGNGRMGQQIAGIVNASDANVIHKVLDVSDAVTPEVFEGSDAIIDFTVRDAFLANYKAMIASGVPVVVGTTGWDE
LMPQIAEEVNAAGSSMLYSANFSLGVNVFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAAQEVLNNNPRK
RTIVRELEDGKKLQSDELQVSSIRLGTVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLAQQHAAKPGFYTMD
DFLNDLFSA
>Mature_249_residues
MKVTLVGNGRMGQQIAGIVNASDANVIHKVLDVSDAVTPEVFEGSDAIIDFTVRDAFLANYKAMIASGVPVVVGTTGWDE
LMPQIAEEVNAAGSSMLYSANFSLGVNVFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAAQEVLNNNPRK
RTIVRELEDGKKLQSDELQVSSIRLGTVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLAQQHAAKPGFYTMD
DFLNDLFSA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=203, Percent_Identity=32.512315270936, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLP8 (B3QKY9)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997977.1
- GeneID:   6419266
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0353
- HOGENOM:   HBG594002
- OMA:   KYLAKIM
- ProtClustDB:   CLSK637968
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26889; Mature: 26889

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLVGNGRMGQQIAGIVNASDANVIHKVLDVSDAVTPEVFEGSDAIIDFTVRDAFLAN
CEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEHHHHHHHH
YKAMIASGVPVVVGTTGWDELMPQIAEEVNAAGSSMLYSANFSLGVNVFFRTLREAARLI
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
APFEQFDIALSEQHHTGKADFPSGTAIKAAQEVLNNNPRKRTIVRELEDGKKLQSDELQV
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEE
SSIRLGTVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLAQQHAAKPGFYTMD
EEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHH
DFLNDLFSA
HHHHHHHCC
>Mature Secondary Structure
MKVTLVGNGRMGQQIAGIVNASDANVIHKVLDVSDAVTPEVFEGSDAIIDFTVRDAFLAN
CEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEHHHHHHHH
YKAMIASGVPVVVGTTGWDELMPQIAEEVNAAGSSMLYSANFSLGVNVFFRTLREAARLI
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
APFEQFDIALSEQHHTGKADFPSGTAIKAAQEVLNNNPRKRTIVRELEDGKKLQSDELQV
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEE
SSIRLGTVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLAQQHAAKPGFYTMD
EEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHH
DFLNDLFSA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA