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The map label for this gene is aroA

Identifier: 193211963

GI number: 193211963

Start: 308797

End: 310101

Strand: Direct

Name: aroA

Synonym: Cpar_0290

Alternate gene names: 193211963

Gene position: 308797-310101 (Clockwise)

Preceding gene: 193211962

Following gene: 193211964

Centisome position: 13.49

GC content: 64.67

Gene sequence:

>1305_bases
ATGAGCGTCTTTCAGGGCGAAGTTTCGAGCCTTCCGCCGGATAAATCGATATCGCATCGCGCAGCCATCATCGGTTCGCT
TGCCGAAGGAACGACCGAAATCACCAACTTTTCGGGCGGATTCGACAACCAATCGACCCTGTCGGTGCTGCGGGATCTCG
GAATCTCTGTCCGGCAGGATGAAGTTCCCGCTGGTGACGGTCGGATCGTCCGGCATGTCGTCATCGAATCGAACGGGCTC
TGGAGCTTCCGCGAGCCGTCGGAGCCGCTGATGTGCAACAACTCCGGCAGCACGATGCGCATGATGGCGGGCATCCTCGC
CGCGCAGCCCTTCCGGAGCGAGCTGGTCGGCGACGCCTCGTTGATGAAGCGCCCGATGAAGCGCGTGGCCGATCCGCTGC
GGATGATGGGCGCGGACATTTCGCTCTCCGACGCCGGAACCGCGCCGGTGGTCATCAATGGCACGAAGGATTTGAAAACC
ATCGAGTACCTGCTTCCGGTTCCGTCGGCGCAGGTCAAGTCGCTCGTGGCGCTGGCCGCGCTGCACGCCGATGGCCAGTC
GAAGATCATCGAGCCGATCCGCTCCCGCGACCACACCGAGCTGATGCTGGGCCTCGAAACCATCGACCGCCCCGACGGCG
TGCGCGAAATCATCATCGACGGGCGCAAGCCGATTGCGGCCAAACCGTTCAAGGTGCCCGCCGATCCATCGGCAGCGTGC
TTCATGATCGCCCTCGGCCTGCTCGGCGAGCGCTCGGAAATCGTGCTGCGCGACGTCTGCCTCAACCCGACGCGCGTGGC
CTACATCGACGTGCTTCAGGAGGCGGGCGCGGGCCTCGGCATCGAGAACGTGCGCTCGGAGGGCGGCGAACCGGTGGGCG
ACATCGTCGTACGGAGCTGCTCTAGCCTCGCGCCGCTGCGCATCAGCGACCACGCGGTGGTGGCGGGCGTGATCGACGAA
CTGCCGATGCTCGCCGTGCTCTCGGCCTTCGCCACAGGGGAGTTCGAGCTGCACAACGCCACCGAGCTGCGCACCAAGGA
GAGCGACCGCATCGAGGCGGTGGTGAGCAATCTGGAGCGCCTCGGCTTTGCGTGTGAGCAGTACCCCGACGGTTTCGTGG
TGAAGGGACGTCCGACGGTCAACCGCGAAGAAGCTGTCATCGAGTGTTTCGACGACCACCGCATCGCCATGAGCTTCGCC
ATCGCCGCCGAAGCCGCAGGCGCATCGCTGCGCCTCTCGGATCGCGAAGTGGCGGGCGTCTCGTTCCCGAACTTCTTCGC
ACTGATCGAGTCGTTGAAGCAGTAG

Upstream 100 bases:

>100_bases
ATTCCCGCTTGCGCGGGAATGACGGATAAAATCGAGACCTTGTTTTACTGTTGTACATTGTTTTTTAAGACAGCCTTTTT
TCAACCAAAATCACGCATCC

Downstream 100 bases:

>100_bases
GTTTTAGTATTCAGGAGTCCCGAAAGCTTTCGGGATGACGGACATTCAATGCTTACATTTTCTTCAGTTGCCCCGGAACT
TTAGTCCGGGGTTGATGAAT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSVFQGEVSSLPPDKSISHRAAIIGSLAEGTTEITNFSGGFDNQSTLSVLRDLGISVRQDEVPAGDGRIVRHVVIESNGL
WSFREPSEPLMCNNSGSTMRMMAGILAAQPFRSELVGDASLMKRPMKRVADPLRMMGADISLSDAGTAPVVINGTKDLKT
IEYLLPVPSAQVKSLVALAALHADGQSKIIEPIRSRDHTELMLGLETIDRPDGVREIIIDGRKPIAAKPFKVPADPSAAC
FMIALGLLGERSEIVLRDVCLNPTRVAYIDVLQEAGAGLGIENVRSEGGEPVGDIVVRSCSSLAPLRISDHAVVAGVIDE
LPMLAVLSAFATGEFELHNATELRTKESDRIEAVVSNLERLGFACEQYPDGFVVKGRPTVNREEAVIECFDDHRIAMSFA
IAAEAAGASLRLSDREVAGVSFPNFFALIESLKQ

Sequences:

>Translated_434_residues
MSVFQGEVSSLPPDKSISHRAAIIGSLAEGTTEITNFSGGFDNQSTLSVLRDLGISVRQDEVPAGDGRIVRHVVIESNGL
WSFREPSEPLMCNNSGSTMRMMAGILAAQPFRSELVGDASLMKRPMKRVADPLRMMGADISLSDAGTAPVVINGTKDLKT
IEYLLPVPSAQVKSLVALAALHADGQSKIIEPIRSRDHTELMLGLETIDRPDGVREIIIDGRKPIAAKPFKVPADPSAAC
FMIALGLLGERSEIVLRDVCLNPTRVAYIDVLQEAGAGLGIENVRSEGGEPVGDIVVRSCSSLAPLRISDHAVVAGVIDE
LPMLAVLSAFATGEFELHNATELRTKESDRIEAVVSNLERLGFACEQYPDGFVVKGRPTVNREEAVIECFDDHRIAMSFA
IAAEAAGASLRLSDREVAGVSFPNFFALIESLKQ
>Mature_433_residues
SVFQGEVSSLPPDKSISHRAAIIGSLAEGTTEITNFSGGFDNQSTLSVLRDLGISVRQDEVPAGDGRIVRHVVIESNGLW
SFREPSEPLMCNNSGSTMRMMAGILAAQPFRSELVGDASLMKRPMKRVADPLRMMGADISLSDAGTAPVVINGTKDLKTI
EYLLPVPSAQVKSLVALAALHADGQSKIIEPIRSRDHTELMLGLETIDRPDGVREIIIDGRKPIAAKPFKVPADPSAACF
MIALGLLGERSEIVLRDVCLNPTRVAYIDVLQEAGAGLGIENVRSEGGEPVGDIVVRSCSSLAPLRISDHAVVAGVIDEL
PMLAVLSAFATGEFELHNATELRTKESDRIEAVVSNLERLGFACEQYPDGFVVKGRPTVNREEAVIECFDDHRIAMSFAI
AAEAAGASLRLSDREVAGVSFPNFFALIESLKQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=24.0825688073394, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_CHLP8 (B3QQU6)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997916.1
- GeneID:   6419203
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0290
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46571; Mature: 46440

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFQGEVSSLPPDKSISHRAAIIGSLAEGTTEITNFSGGFDNQSTLSVLRDLGISVRQD
CCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHCCCEEECC
EVPAGDGRIVRHVVIESNGLWSFREPSEPLMCNNSGSTMRMMAGILAAQPFRSELVGDAS
CCCCCCCEEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHCCCHH
LMKRPMKRVADPLRMMGADISLSDAGTAPVVINGTKDLKTIEYLLPVPSAQVKSLVALAA
HHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHHH
LHADGQSKIIEPIRSRDHTELMLGLETIDRPDGVREIIIDGRKPIAAKPFKVPADPSAAC
HHCCCHHHHHHHHHCCCCHHEEEEHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHH
FMIALGLLGERSEIVLRDVCLNPTRVAYIDVLQEAGAGLGIENVRSEGGEPVGDIVVRSC
HHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHH
SSLAPLRISDHAVVAGVIDELPMLAVLSAFATGEFELHNATELRTKESDRIEAVVSNLER
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHCCCCHHHHHHHHHHHHH
LGFACEQYPDGFVVKGRPTVNREEAVIECFDDHRIAMSFAIAAEAAGASLRLSDREVAGV
HCCHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEECCCCCCCC
SFPNFFALIESLKQ
CCHHHHHHHHHHCC
>Mature Secondary Structure 
SVFQGEVSSLPPDKSISHRAAIIGSLAEGTTEITNFSGGFDNQSTLSVLRDLGISVRQD
CCCCCCHHCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHCCCEEECC
EVPAGDGRIVRHVVIESNGLWSFREPSEPLMCNNSGSTMRMMAGILAAQPFRSELVGDAS
CCCCCCCEEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHCCCHH
LMKRPMKRVADPLRMMGADISLSDAGTAPVVINGTKDLKTIEYLLPVPSAQVKSLVALAA
HHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHHH
LHADGQSKIIEPIRSRDHTELMLGLETIDRPDGVREIIIDGRKPIAAKPFKVPADPSAAC
HHCCCHHHHHHHHHCCCCHHEEEEHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHH
FMIALGLLGERSEIVLRDVCLNPTRVAYIDVLQEAGAGLGIENVRSEGGEPVGDIVVRSC
HHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHH
SSLAPLRISDHAVVAGVIDELPMLAVLSAFATGEFELHNATELRTKESDRIEAVVSNLER
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHCCCCHHHHHHHHHHHHH
LGFACEQYPDGFVVKGRPTVNREEAVIECFDDHRIAMSFAIAAEAAGASLRLSDREVAGV
HCCHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEECCCCCCCC
SFPNFFALIESLKQ
CCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA