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The map label for this gene is 193211943

Identifier: 193211943

GI number: 193211943

Start: 287434

End: 288651

Strand: Direct

Name: 193211943

Synonym: Cpar_0269

Alternate gene names: NA

Gene position: 287434-288651 (Clockwise)

Preceding gene: 193211939

Following gene: 193211944

Centisome position: 12.56

GC content: 52.22

Gene sequence:

>1218_bases
ATGCGTATATTAACTTTTACTGGTAAAGGTGGTGTGGGAAAGACAAGCGTCTCGGCCGCCACGGCAGTCCGTCTTTCCGA
GATGGGACATCGCACGCTGGTGCTTTCGACCGACCCTGCCCACAGCCTTTCAGACTCTTTCAACCTTCAACTTGGCGCTG
AGCCGACCAAGATCAAGGAAAACCTTCACGCCATCGAGGTAAACCCTTACGTTGACCTCAAGGAGAACTGGCATTCGGTA
CAGAAGTACTACACTCGCGTTTTCATGGCTCAGGGCGTCTCTGGCGTCATGGCTGACGAAATGACGATTCTTCCCGGCAT
GGAAGAGCTCTTCTCCCTGCTCAGAATCAAACGCTACAAATCCACCGGCCTGTACGATGCGCTCGTGCTCGATACGGCTC
CGACCGGCGAAACCCTTCGCCTGCTCTCGCTTCCCGATACCCTTTCATGGGGCATGAAGGCGGTGAAAAACGTCAATAAA
TATATTGTTCGTCCGCTCAGCAAGCCGCTGTCCAAAATGTCGGACAAAATTGCCTACTACATTCCGCCGGAAGACGCTAT
CGAATCTGTCGATCAGGTGTTCGACGAACTCGAAGACATTCGGGATATTCTGACCGACAACGTCAAGTCGACCGTCAGGC
TGGTTATGAACGCCGAGAAAATGTCGATCAAGGAGACCATGCGCGCCCTGACCTACCTGAACCTCTATGGCTTCAAGGTC
GATATGGTGCTGGTCAACAAGCTGCTCGACGCACAGGAGAACAGCGGTTACCTCGAAAAGTGGAAAGGCATCCAGCAAAA
ATATCTTGGCGAGATCGAAGAGGGCTTTTCGCCGCTTCCGGTCAAAAAGCTGAAGATGTATGATCAGGAGATCGTCGGCG
TCAAATCGCTCGAAGTGTTTGCCCATGATATTTATGGTGACACCGATCCATCCGATATGATGTATGACGAGCCGCCGATC
AAGTTTGTTCGCAAGGGCGATATCTATGAAGTTCAGCTCAAGCTCATGTTTGCCAACCCGGTCGATATCGATGTGTGGGT
TACCGGTGACGAGCTGTTTGTCCAGATTGGCAACCAGCGCAAGATCATTACGCTTCCGGTCAGCCTTACCGGTCTGGAAC
CCGGCGATGCCGTCTTCCGTGACAAGTGGCTGCACATTCCCTTCGATCTCGAAAAGCAGGGCCAGCATCACCGTACCAGA
GAGTTTAACAAAGCTTAA

Upstream 100 bases:

>100_bases
GTTCCGGGCGCGGATTGTTTGTGAATGGTGCTTTGCAGAATGATTGGATAAGTATATCTTAACGATCTTGGCTGTATAAT
AAACTTCCAATGCCTGGTTC

Downstream 100 bases:

>100_bases
TGTGGCACGGATTCCTGTTTGAGCAAGGGCGATTTTTTTATTAGTTTCGTTCAAAGTCGTTTTACACATAACAGTAACTC
CGGGCTGCCAAGGCGGTCGG

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKENLHAIEVNPYVDLKENWHSV
QKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSTGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSDMMYDEPPI
KFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTR
EFNKA

Sequences:

>Translated_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKENLHAIEVNPYVDLKENWHSV
QKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSTGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSDMMYDEPPI
KFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTR
EFNKA
>Mature_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKENLHAIEVNPYVDLKENWHSV
QKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYKSTGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIVRPLSKPLSKMSDKIAYYIPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVFAHDIYGDTDPSDMMYDEPPI
KFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQRKIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTR
EFNKA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=290, Percent_Identity=27.2413793103448, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17557003, Length=303, Percent_Identity=26.7326732673267, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320103, Length=317, Percent_Identity=28.7066246056782, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24586297, Length=302, Percent_Identity=28.1456953642384, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45936; Mature: 45936

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHC
NLHAIEVNPYVDLKENWHSVQKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHC
STGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIVRPLSKPLSKMSDKIAYY
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
AHDIYGDTDPSDMMYDEPPIKFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQR
HHHHCCCCCCCCCCCCCCCHHEEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTREFNKA
EEEEEEEEEECCCCCCHHHHCCEEECCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCHHHHC
NLHAIEVNPYVDLKENWHSVQKYYTRVFMAQGVSGVMADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHC
STGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIVRPLSKPLSKMSDKIAYY
CCCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IPPEDAIESVDQVFDELEDIRDILTDNVKSTVRLVMNAEKMSIKETMRALTYLNLYGFKV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
DMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPVKKLKMYDQEIVGVKSLEVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
AHDIYGDTDPSDMMYDEPPIKFVRKGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGNQR
HHHHCCCCCCCCCCCCCCCHHEEECCCEEEEEEEEEEECCCEEEEEEECCEEEEEECCCC
KIITLPVSLTGLEPGDAVFRDKWLHIPFDLEKQGQHHRTREFNKA
EEEEEEEEEECCCCCCHHHHCCEEECCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]