Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 193211872

GI number: 193211872

Start: 200612

End: 201385

Strand: Direct

Name: map [H]

Synonym: Cpar_0198

Alternate gene names: 193211872

Gene position: 200612-201385 (Clockwise)

Preceding gene: 193211871

Following gene: 193211873

Centisome position: 8.76

GC content: 57.88

Gene sequence:

>774_bases
ATGATCACCATCAAAAGCGAGCGTGAAATCGGGTTGATGCGCGAGGCTGGCGAAATCGTCGGTCGCGTTCTCGACATGCT
CGAAGAGGAAATTGCTCCAGGTATGACGACCAAGCGGCTCGACGAGCTTGCCGAGCAGTTCATTCGCGATCATCAGGCCG
TGCCGAGTTTTCTGAATTACGCGCCGAAAGGCGAGCCCAATGTGACGCCTTACCCGGCCACCCTGTGCGTCTCGATCAAT
GAAGAGGTTGTGCATGGCGTGCCGAGCGACAAGCGTGTGATTCAGGAAGGTGAGATCGTTTCGGTCGATTGCGGAGCTTA
CAAAAGCGGTTACCACGGCGATTCTGCCCGAACGTTTGTGGTTGGAGAGATCGCCCCCGAGGTTCAGCAGCTTGTCGATG
TGACGCGCGAATGCCTCTATCGCGGTATTGAGCAGGCCGTTGCAGGCAACCGTCTGCACGACATTTCGGCGGCCATCGAG
AAGCATGCGCGCTCGTTCAATTACAGTGTGATCGAGAACATGGTCGGCCATGGAATCGGCAGCGAACTGCATGAGGACCC
TGCCGTTCCGAATTATGGACGGCCGCATACCGGTGTGAAGTTGCGCAAGGGAATGACGCTGGCCATCGAGCCGATGATTG
CCCTTGGCCGCTCTCGACGTGCGGTCAGTAAACGAGGCGCCTGGGTTGCTGTAACCGAAGACGGCAAGCCGTCAGCCCAT
TTCGAGCACACCATCGCCATCGGTGACGGCCCTGCCGAAATTCTGACCCGGTAA

Upstream 100 bases:

>100_bases
TTGTCAGCGTCGGCCTCGACACGCTTCAGCAGGTCGAAAGCCATCTGATGATGCGCCACTACGACGGGTTCATGAAGACC
GCGAAGGCTCGGGGGCGTCG

Downstream 100 bases:

>100_bases
GCAACAGAGAGCACTATTTATAACGAACTGAAGAAAAGCGGAGAGAGACAGTGGCCAAGGAAGAATCAATTGAGGTAGAA
GGCGAAATTCTGGAAGCGCT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MITIKSEREIGLMREAGEIVGRVLDMLEEEIAPGMTTKRLDELAEQFIRDHQAVPSFLNYAPKGEPNVTPYPATLCVSIN
EEVVHGVPSDKRVIQEGEIVSVDCGAYKSGYHGDSARTFVVGEIAPEVQQLVDVTRECLYRGIEQAVAGNRLHDISAAIE
KHARSFNYSVIENMVGHGIGSELHEDPAVPNYGRPHTGVKLRKGMTLAIEPMIALGRSRRAVSKRGAWVAVTEDGKPSAH
FEHTIAIGDGPAEILTR

Sequences:

>Translated_257_residues
MITIKSEREIGLMREAGEIVGRVLDMLEEEIAPGMTTKRLDELAEQFIRDHQAVPSFLNYAPKGEPNVTPYPATLCVSIN
EEVVHGVPSDKRVIQEGEIVSVDCGAYKSGYHGDSARTFVVGEIAPEVQQLVDVTRECLYRGIEQAVAGNRLHDISAAIE
KHARSFNYSVIENMVGHGIGSELHEDPAVPNYGRPHTGVKLRKGMTLAIEPMIALGRSRRAVSKRGAWVAVTEDGKPSAH
FEHTIAIGDGPAEILTR
>Mature_257_residues
MITIKSEREIGLMREAGEIVGRVLDMLEEEIAPGMTTKRLDELAEQFIRDHQAVPSFLNYAPKGEPNVTPYPATLCVSIN
EEVVHGVPSDKRVIQEGEIVSVDCGAYKSGYHGDSARTFVVGEIAPEVQQLVDVTRECLYRGIEQAVAGNRLHDISAAIE
KHARSFNYSVIENMVGHGIGSELHEDPAVPNYGRPHTGVKLRKGMTLAIEPMIALGRSRRAVSKRGAWVAVTEDGKPSAH
FEHTIAIGDGPAEILTR

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=256, Percent_Identity=38.28125, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI40385867, Length=256, Percent_Identity=33.203125, Blast_Score=144, Evalue=7e-35,
Organism=Escherichia coli, GI1786364, Length=256, Percent_Identity=38.28125, Blast_Score=184, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=32.5581395348837, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6323273, Length=256, Percent_Identity=37.109375, Blast_Score=167, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24583427, Length=254, Percent_Identity=36.2204724409449, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355531, Length=256, Percent_Identity=34.765625, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28101; Mature: 28101

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKSEREIGLMREAGEIVGRVLDMLEEEIAPGMTTKRLDELAEQFIRDHQAVPSFLNY
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
APKGEPNVTPYPATLCVSINEEVVHGVPSDKRVIQEGEIVSVDCGAYKSGYHGDSARTFV
CCCCCCCCCCCCCEEEEECCHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
VGEIAPEVQQLVDVTRECLYRGIEQAVAGNRLHDISAAIEKHARSFNYSVIENMVGHGIG
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
SELHEDPAVPNYGRPHTGVKLRKGMTLAIEPMIALGRSRRAVSKRGAWVAVTEDGKPSAH
CHHHCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHCCHHHHHHHCCCEEEEECCCCCCCC
FEHTIAIGDGPAEILTR
EEEEEEECCCHHHHHCC
>Mature Secondary Structure
MITIKSEREIGLMREAGEIVGRVLDMLEEEIAPGMTTKRLDELAEQFIRDHQAVPSFLNY
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
APKGEPNVTPYPATLCVSINEEVVHGVPSDKRVIQEGEIVSVDCGAYKSGYHGDSARTFV
CCCCCCCCCCCCCEEEEECCHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
VGEIAPEVQQLVDVTRECLYRGIEQAVAGNRLHDISAAIEKHARSFNYSVIENMVGHGIG
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
SELHEDPAVPNYGRPHTGVKLRKGMTLAIEPMIALGRSRRAVSKRGAWVAVTEDGKPSAH
CHHHCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHCCHHHHHHHCCCEEEEECCCCCCCC
FEHTIAIGDGPAEILTR
EEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]