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The map label for this gene is comF [H]

Identifier: 193214264

GI number: 193214264

Start: 644716

End: 645426

Strand: Direct

Name: comF [H]

Synonym: Ctha_0545

Alternate gene names: 193214264

Gene position: 644716-645426 (Clockwise)

Preceding gene: 193214263

Following gene: 193214266

Centisome position: 19.58

GC content: 41.49

Gene sequence:

>711_bases
ATGACGCGATTTTTAGATCGTTGCCTGCGCGAAGCGCTTCATCTTATTTATCCTCATGTTTGTATTTGCTGCCACACACT
TCTTGAAGAAAGTGAGAACTATGTCTGCAAAACCTGTTACGAGCAGTTAGATAAGTTTTTACTCCCAGGAGAATCAGCAA
CAGAAATTTCCGCCAGGCTCGCCAAACATTTTCCATTTCAAACATCTATAAAAGAAGGGCTCGCCCTATATCGTTTTCAC
AAATCAGGTCTACTTCAAGAGATCATTCACAGCATCAAGTATGGTGGATTGCAAAATCTTGCTGTTGAACTCGGAATGAT
GCTTGGGAAGCATATTTTAAGCGAAAAACCCTTTTCTACTTGGGAGGCAATTATTCCTGTACCACTTCACCATGTAAAAC
ACATTGAACGCGGGTACAATCAGGCAGAGGCATTAGCAAATGGGGTAAGCCGGGCTATAGGAATACCTGTAGTGCGAAAC
GCAGTTATGAGATCAAGATACACAGAATCACAAACAAAACTTGCTGCAGAAAAACGCCGAGCAAATATATCCGGCGTGTT
TCAAATCCGTCAGCCCGTTCAGTTCAAACAAATTTTATTAATCGATGATGTTTTTACAACAGGAGCTACTTTAGTTGAAC
TCAGCCATGAGCTCAAAAAATATGGCGCCATTGAAATCACAATAGCAGCTCTTGCCGTAACAAGCACCTAA

Upstream 100 bases:

>100_bases
CGTCATGACTGTAATTCCGCCTTGTTCAAAAAAAATCAACGCATTATAAAGAGTCTTTTTTTTATTTTTTCCCAATTTTG
TTGAATAAAACCCCCTAGAT

Downstream 100 bases:

>100_bases
ACATCCTTTTGAATGAATTTTTCAATAGGATTTATTCAAGCTATCCGAATAAACCGGCCAGAAGGCGAAATTGCATCGTG
GCAAATTCGGAACTAATGAC

Product: competence protein

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTRFLDRCLREALHLIYPHVCICCHTLLEESENYVCKTCYEQLDKFLLPGESATEISARLAKHFPFQTSIKEGLALYRFH
KSGLLQEIIHSIKYGGLQNLAVELGMMLGKHILSEKPFSTWEAIIPVPLHHVKHIERGYNQAEALANGVSRAIGIPVVRN
AVMRSRYTESQTKLAAEKRRANISGVFQIRQPVQFKQILLIDDVFTTGATLVELSHELKKYGAIEITIAALAVTST

Sequences:

>Translated_236_residues
MTRFLDRCLREALHLIYPHVCICCHTLLEESENYVCKTCYEQLDKFLLPGESATEISARLAKHFPFQTSIKEGLALYRFH
KSGLLQEIIHSIKYGGLQNLAVELGMMLGKHILSEKPFSTWEAIIPVPLHHVKHIERGYNQAEALANGVSRAIGIPVVRN
AVMRSRYTESQTKLAAEKRRANISGVFQIRQPVQFKQILLIDDVFTTGATLVELSHELKKYGAIEITIAALAVTST
>Mature_235_residues
TRFLDRCLREALHLIYPHVCICCHTLLEESENYVCKTCYEQLDKFLLPGESATEISARLAKHFPFQTSIKEGLALYRFHK
SGLLQEIIHSIKYGGLQNLAVELGMMLGKHILSEKPFSTWEAIIPVPLHHVKHIERGYNQAEALANGVSRAIGIPVVRNA
VMRSRYTESQTKLAAEKRRANISGVFQIRQPVQFKQILLIDDVFTTGATLVELSHELKKYGAIEITIAALAVTST

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=231, Percent_Identity=26.8398268398268, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26585; Mature: 26454

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFLDRCLREALHLIYPHVCICCHTLLEESENYVCKTCYEQLDKFLLPGESATEISARL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AKHFPFQTSIKEGLALYRFHKSGLLQEIIHSIKYGGLQNLAVELGMMLGKHILSEKPFST
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
WEAIIPVPLHHVKHIERGYNQAEALANGVSRAIGIPVVRNAVMRSRYTESQTKLAAEKRR
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANISGVFQIRQPVQFKQILLIDDVFTTGATLVELSHELKKYGAIEITIAALAVTST
CCHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHEECCC
>Mature Secondary Structure 
TRFLDRCLREALHLIYPHVCICCHTLLEESENYVCKTCYEQLDKFLLPGESATEISARL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AKHFPFQTSIKEGLALYRFHKSGLLQEIIHSIKYGGLQNLAVELGMMLGKHILSEKPFST
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
WEAIIPVPLHHVKHIERGYNQAEALANGVSRAIGIPVVRNAVMRSRYTESQTKLAAEKRR
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANISGVFQIRQPVQFKQILLIDDVFTTGATLVELSHELKKYGAIEITIAALAVTST
CCHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]