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The map label for this gene is aroB [H]

Identifier: 193214195

GI number: 193214195

Start: 559640

End: 560569

Strand: Direct

Name: aroB [H]

Synonym: Ctha_0476

Alternate gene names: 193214195

Gene position: 559640-560569 (Clockwise)

Preceding gene: 193214191

Following gene: 193214196

Centisome position: 16.99

GC content: 47.74

Gene sequence:

>930_bases
ATGCCTAAAATCGCAACCATTGATATTGGGACAAACACGGCTTTGCTGCTTATTGCTGAATTTGACTTGGCAACCAAGCA
GTTACACACAATTCTTAACCAAATCGAAGTCGTTAGACTTGGCCAAGGCGTTGATAAAGAGCGTCGGATTACAGCCGAAT
CCATCAGTCGGCTTGTTTTGGCAATGGCCAAGTTTAAATCTACCATTCAAGCACACGGCGTGGAAAAAACTTACGCGGTT
GCAACCAGCGCCATGCGCGATGCCCAGAATCGCGATGATGTGATTCAAACGGTGCAGGAACAAACCGGCATTGACATTGA
ACTGCTTAAGGGAGAAGCAGAAGCCGACATGACCTTTCTTGGCGCAACCATTGGTTGGAGAAACTTGCCGAAAAAATTTC
TTGTCATCGACATCGGCGGCGGCAGTACGGAAATCGCACTTGGCGACCAAAACGGCATCATCGATGGCGTCAGTCTCAAT
ATCGGCGCGGTAAGATTGGTGGAGCGCTGCTTTAGCACAATTCCGCCAAAGCCGGCTGAACTTGAAGCGGCCAAAGACAT
TATCACGAAGGCCTTAAGCGCACCGCTTTCTCGATTCATCCAAGGACGCGAAAGTGTTTTTGCAGTTGCTGGCACACCTG
CCACACTTGCAAAAGTCATTCAAAAACTTCCCGATTTTCTCCCCGATCGAATTCACGGTTTTGAATTGACTTACGCTCAT
GTTCACTCGTTGCTTGACGCATTCAGCAAAAGCACAACTGAGCAGATTTTGGAAATGGGCGTAGAGCCAGGCCGCGAAGA
CTTGATTGTTGTGGGAACGATGATTTTACACCAATTCATGAGAATTTTCGGCGTGCCTTCGGTTCGCGTTAGCATTCAAG
GACTTCGCTACGGTGTTGCAGCAAGAAAAGCGAATGAATTCCTTAAATAA

Upstream 100 bases:

>100_bases
CTGCTTTCTTTCCACAAAAGATTTCACGCATCGCTGCTGATTATCTGCTCGGCTTGTTTTATTTTCTCGCAAAAATTAAC
TGATTTTATCAAAATTGACT

Downstream 100 bases:

>100_bases
ATAGCGTTAGTTTATTTTCACCAAAAGAGCCAGAACTTGTTAGGGCGCATTCTGAATGGCAGGTGAAAATTTTTTAATGC
GCAGAAAGTTATTCGGTTTA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPKIATIDIGTNTALLLIAEFDLATKQLHTILNQIEVVRLGQGVDKERRITAESISRLVLAMAKFKSTIQAHGVEKTYAV
ATSAMRDAQNRDDVIQTVQEQTGIDIELLKGEAEADMTFLGATIGWRNLPKKFLVIDIGGGSTEIALGDQNGIIDGVSLN
IGAVRLVERCFSTIPPKPAELEAAKDIITKALSAPLSRFIQGRESVFAVAGTPATLAKVIQKLPDFLPDRIHGFELTYAH
VHSLLDAFSKSTTEQILEMGVEPGREDLIVVGTMILHQFMRIFGVPSVRVSIQGLRYGVAARKANEFLK

Sequences:

>Translated_309_residues
MPKIATIDIGTNTALLLIAEFDLATKQLHTILNQIEVVRLGQGVDKERRITAESISRLVLAMAKFKSTIQAHGVEKTYAV
ATSAMRDAQNRDDVIQTVQEQTGIDIELLKGEAEADMTFLGATIGWRNLPKKFLVIDIGGGSTEIALGDQNGIIDGVSLN
IGAVRLVERCFSTIPPKPAELEAAKDIITKALSAPLSRFIQGRESVFAVAGTPATLAKVIQKLPDFLPDRIHGFELTYAH
VHSLLDAFSKSTTEQILEMGVEPGREDLIVVGTMILHQFMRIFGVPSVRVSIQGLRYGVAARKANEFLK
>Mature_308_residues
PKIATIDIGTNTALLLIAEFDLATKQLHTILNQIEVVRLGQGVDKERRITAESISRLVLAMAKFKSTIQAHGVEKTYAVA
TSAMRDAQNRDDVIQTVQEQTGIDIELLKGEAEADMTFLGATIGWRNLPKKFLVIDIGGGSTEIALGDQNGIIDGVSLNI
GAVRLVERCFSTIPPKPAELEAAKDIITKALSAPLSRFIQGRESVFAVAGTPATLAKVIQKLPDFLPDRIHGFELTYAHV
HSLLDAFSKSTTEQILEMGVEPGREDLIVVGTMILHQFMRIFGVPSVRVSIQGLRYGVAARKANEFLK

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=171, Percent_Identity=30.9941520467836, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788848, Length=301, Percent_Identity=24.5847176079734, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33657; Mature: 33525

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIATIDIGTNTALLLIAEFDLATKQLHTILNQIEVVRLGQGVDKERRITAESISRLVL
CCCEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AMAKFKSTIQAHGVEKTYAVATSAMRDAQNRDDVIQTVQEQTGIDIELLKGEAEADMTFL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
GATIGWRNLPKKFLVIDIGGGSTEIALGDQNGIIDGVSLNIGAVRLVERCFSTIPPKPAE
HHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCH
LEAAKDIITKALSAPLSRFIQGRESVFAVAGTPATLAKVIQKLPDFLPDRIHGFELTYAH
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCHHHHCCCCHHHHH
VHSLLDAFSKSTTEQILEMGVEPGREDLIVVGTMILHQFMRIFGVPSVRVSIQGLRYGVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ARKANEFLK
HHHHHHHCC
>Mature Secondary Structure 
PKIATIDIGTNTALLLIAEFDLATKQLHTILNQIEVVRLGQGVDKERRITAESISRLVL
CCEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AMAKFKSTIQAHGVEKTYAVATSAMRDAQNRDDVIQTVQEQTGIDIELLKGEAEADMTFL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
GATIGWRNLPKKFLVIDIGGGSTEIALGDQNGIIDGVSLNIGAVRLVERCFSTIPPKPAE
HHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCH
LEAAKDIITKALSAPLSRFIQGRESVFAVAGTPATLAKVIQKLPDFLPDRIHGFELTYAH
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCHHHHCCCCHHHHH
VHSLLDAFSKSTTEQILEMGVEPGREDLIVVGTMILHQFMRIFGVPSVRVSIQGLRYGVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ARKANEFLK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]