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The map label for this gene is add5 [H]

Identifier: 193214077

GI number: 193214077

Start: 411474

End: 412580

Strand: Direct

Name: add5 [H]

Synonym: Ctha_0358

Alternate gene names: 193214077

Gene position: 411474-412580 (Clockwise)

Preceding gene: 193214075

Following gene: 193214078

Centisome position: 12.49

GC content: 50.05

Gene sequence:

>1107_bases
ATGCAAAAAATACTTTCTGATGAGATGCTCAATCGTATGCCAAAGGTCTTGCTTCACGACCATTTGGATGGAAGCGTGAG
AGCAAGCACGGTTGTTGAACTGGCAAAATCCCAAAACTACAGCGCGCTGCCCACCATGAACGCCGATGAACTTTCAGACT
GGTTTCATCGCGGCGCAAACAAAGGCAGCTTGCCGGAGTATCTTTCTGGATTTGTGCACACCTGCGCTGTGATGCAAACG
CCCGAAGCGCTCGAGCGCGCTGCTTACGAACATGTGGAAGATTGCCAAAAAGACGGCGTTTGCTATGTGGAAGTTCGTTT
TGCGCCATCTTTGCACACAGCAAACGGCATGCACTGGGATGAAGTGGTCAATAGCGTGCTGAAAGGGTTCGATCGTGGCG
AGCGCGACTTTGGCATTACCGCGCGGCTTATCATCTGTGCGCTGCGGCATTTGGACAGCCATCATTCTGAAGACATGGCG
CAGCTCGCCGTCGATTTTCGCGATAAAGGCGTTGTCGGGTTTGACTTGGCCGGCGAAGAAGGCGGCTATCCGCCAAAAAA
GCATTTGAGTGCGTTTCATTTTTGCCAACGCGCCAATTTCAATCTTACGATTCATGCAGGCGAAGGCTTTGGGAAAGAAT
CCATTTGGCAAGCCATTCAATGGTGCGGCGCACATCGCATTGGTCATGCCACGCGGCTCATCGACGATATGGCCGTGCAT
GAAAACGAAGTCATCAAAATGGGCTCGCTGGCACAATATGTTTTGGATAAGCGCATTCCGCTCGAGATCTGCCTCTCGTC
CAATATTCACACAGGCGCTGCGGCGTCTTTCGAAACGCATCCGTTTAAAACCTTCTACAATACCAAATTTCGGGTTACGC
TCAACACCGACAACCGATTGATGAGCAACACCAATATGACGCAAGAATACCAAATCGCTCGCGATTTCTACGGCTTCACT
TTCTCCGATTTTGAGCGAATTTCCATTAACAGCATGAAAAGCGCCTTCATTTGCTATCGCGAGCGCTGTGACTTGATTTA
TCATGTCATCAAACCAGCGTTTGCAAAACTGCGAGATGAACTTGCCGCACAAGAAGTTCCCCGCTAA

Upstream 100 bases:

>100_bases
TTACCCTTAGAAACACGCGTCCCAAAACCTGCGTTTATTGACACAAAAATGCGAATGTTTCGAACTGCTTTGCGAAAAAA
GCGATAAAAAAGCCAATCAT

Downstream 100 bases:

>100_bases
TCACAAGCGCGCACCGCTGTTTCGGGGTTGCCATTGCGTTGGTTTTATAGCGATATTTTCATATTTACATTCATTAACCC
TAACACCTCAATCGATTAAG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase 5 [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MQKILSDEMLNRMPKVLLHDHLDGSVRASTVVELAKSQNYSALPTMNADELSDWFHRGANKGSLPEYLSGFVHTCAVMQT
PEALERAAYEHVEDCQKDGVCYVEVRFAPSLHTANGMHWDEVVNSVLKGFDRGERDFGITARLIICALRHLDSHHSEDMA
QLAVDFRDKGVVGFDLAGEEGGYPPKKHLSAFHFCQRANFNLTIHAGEGFGKESIWQAIQWCGAHRIGHATRLIDDMAVH
ENEVIKMGSLAQYVLDKRIPLEICLSSNIHTGAAASFETHPFKTFYNTKFRVTLNTDNRLMSNTNMTQEYQIARDFYGFT
FSDFERISINSMKSAFICYRERCDLIYHVIKPAFAKLRDELAAQEVPR

Sequences:

>Translated_368_residues
MQKILSDEMLNRMPKVLLHDHLDGSVRASTVVELAKSQNYSALPTMNADELSDWFHRGANKGSLPEYLSGFVHTCAVMQT
PEALERAAYEHVEDCQKDGVCYVEVRFAPSLHTANGMHWDEVVNSVLKGFDRGERDFGITARLIICALRHLDSHHSEDMA
QLAVDFRDKGVVGFDLAGEEGGYPPKKHLSAFHFCQRANFNLTIHAGEGFGKESIWQAIQWCGAHRIGHATRLIDDMAVH
ENEVIKMGSLAQYVLDKRIPLEICLSSNIHTGAAASFETHPFKTFYNTKFRVTLNTDNRLMSNTNMTQEYQIARDFYGFT
FSDFERISINSMKSAFICYRERCDLIYHVIKPAFAKLRDELAAQEVPR
>Mature_368_residues
MQKILSDEMLNRMPKVLLHDHLDGSVRASTVVELAKSQNYSALPTMNADELSDWFHRGANKGSLPEYLSGFVHTCAVMQT
PEALERAAYEHVEDCQKDGVCYVEVRFAPSLHTANGMHWDEVVNSVLKGFDRGERDFGITARLIICALRHLDSHHSEDMA
QLAVDFRDKGVVGFDLAGEEGGYPPKKHLSAFHFCQRANFNLTIHAGEGFGKESIWQAIQWCGAHRIGHATRLIDDMAVH
ENEVIKMGSLAQYVLDKRIPLEICLSSNIHTGAAASFETHPFKTFYNTKFRVTLNTDNRLMSNTNMTQEYQIARDFYGFT
FSDFERISINSMKSAFICYRERCDLIYHVIKPAFAKLRDELAAQEVPR

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=354, Percent_Identity=32.4858757062147, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI61175224, Length=227, Percent_Identity=25.5506607929515, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787910, Length=331, Percent_Identity=32.9305135951662, Blast_Score=190, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17538512, Length=357, Percent_Identity=30.812324929972, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=352, Percent_Identity=31.25, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI115537133, Length=342, Percent_Identity=25.1461988304094, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324188, Length=352, Percent_Identity=23.8636363636364, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24645260, Length=343, Percent_Identity=23.3236151603499, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 41727; Mature: 41727

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKILSDEMLNRMPKVLLHDHLDGSVRASTVVELAKSQNYSALPTMNADELSDWFHRGAN
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
KGSLPEYLSGFVHTCAVMQTPEALERAAYEHVEDCQKDGVCYVEVRFAPSLHTANGMHWD
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHH
EVVNSVLKGFDRGERDFGITARLIICALRHLDSHHSEDMAQLAVDFRDKGVVGFDLAGEE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCC
GGYPPKKHLSAFHFCQRANFNLTIHAGEGFGKESIWQAIQWCGAHRIGHATRLIDDMAVH
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
ENEVIKMGSLAQYVLDKRIPLEICLSSNIHTGAAASFETHPFKTFYNTKFRVTLNTDNRL
CCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHEECCEEEEEECCCCCE
MSNTNMTQEYQIARDFYGFTFSDFERISINSMKSAFICYRERCDLIYHVIKPAFAKLRDE
ECCCCCCHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAQEVPR
HHHHCCCC
>Mature Secondary Structure
MQKILSDEMLNRMPKVLLHDHLDGSVRASTVVELAKSQNYSALPTMNADELSDWFHRGAN
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
KGSLPEYLSGFVHTCAVMQTPEALERAAYEHVEDCQKDGVCYVEVRFAPSLHTANGMHWD
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHH
EVVNSVLKGFDRGERDFGITARLIICALRHLDSHHSEDMAQLAVDFRDKGVVGFDLAGEE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCC
GGYPPKKHLSAFHFCQRANFNLTIHAGEGFGKESIWQAIQWCGAHRIGHATRLIDDMAVH
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
ENEVIKMGSLAQYVLDKRIPLEICLSSNIHTGAAASFETHPFKTFYNTKFRVTLNTDNRL
CCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHEECCEEEEEECCCCCE
MSNTNMTQEYQIARDFYGFTFSDFERISINSMKSAFICYRERCDLIYHVIKPAFAKLRDE
ECCCCCCHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAQEVPR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]