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The map label for this gene is ppa [H]

Identifier: 193213966

GI number: 193213966

Start: 294101

End: 294802

Strand: Direct

Name: ppa [H]

Synonym: Ctha_0247

Alternate gene names: 193213966

Gene position: 294101-294802 (Clockwise)

Preceding gene: 193213963

Following gene: 193213967

Centisome position: 8.93

GC content: 43.02

Gene sequence:

>702_bases
ATGGTTAATTATAAGAGCCTCCCAAGCGGACAAAATCCGCCGAAAGAAGTTTATGCTGTGATCGAAGTGCCACAAGGTGA
ACGCAACAAGTATGAATTTGATCCTGATTTATGTGTGTTTAAACTCGATAGGGTTCTTTACGCGTCAGTTCACTACCCAA
CTGGCTATGGATTTATTCCAAGAACTTTAGCGGAAGATGGCGATCCACTGGATGTGATGGTAATGACTCATGGGAGAACA
TTTACCGGATGTTTAATTGAGGTGCGTCCGGTTGGTATGTTGAAAATGCGTGATGACAAAGGGTTAGACCACAAAATCCT
TTCTGTACCAATTAACGATCCAATGTATAGCCACGTCAGAAGACTTTCTGATTTGCCATCGCACTTGCCAACTGAAATCG
AGCACTTTTTCAGCGTTTACAAAGAACTCGAAGGAAAAGCTGTTGAAAGCTTCGGCTGGTACGACTTCTTTACGGCTGAG
CAAACCATCATCGAAGCCATGAAAGCTTATGACGCAGCGAATGAAGAGGCTGATGAAGAAGATGGCAAAAAGAAAAAAAA
GAAGGACAAAAAAGGAAAGAAAGATAAAAAAGGCCACGACGCTGAAGTAGGCGAAACAATGGCGTCTCAAGATTCAGCAC
AAATGGCTTTTGATGGACGCGAAGAAGACATAGAAGAAGGGCACGACGAAACAGTAGCGTAA

Upstream 100 bases:

>100_bases
CCTCTCTTCAGAAAGCCAAGAACAAATCGGAACAAGAATCTGCCTCATAAACCGTTTTAAGCATTTTAAACATCCAAAAA
TATTTATCCAGATAGAAAAT

Downstream 100 bases:

>100_bases
GCTGACGTTTTTTTCGTTCCGAAATGTCCTCGTATAGAAATAGAACCGGCGGTTTCATTTTACATGAAGCGCCGGTTTTT
TTGTATATTTTTCGGCTGTT

Product: Inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVNYKSLPSGQNPPKEVYAVIEVPQGERNKYEFDPDLCVFKLDRVLYASVHYPTGYGFIPRTLAEDGDPLDVMVMTHGRT
FTGCLIEVRPVGMLKMRDDKGLDHKILSVPINDPMYSHVRRLSDLPSHLPTEIEHFFSVYKELEGKAVESFGWYDFFTAE
QTIIEAMKAYDAANEEADEEDGKKKKKKDKKGKKDKKGHDAEVGETMASQDSAQMAFDGREEDIEEGHDETVA

Sequences:

>Translated_233_residues
MVNYKSLPSGQNPPKEVYAVIEVPQGERNKYEFDPDLCVFKLDRVLYASVHYPTGYGFIPRTLAEDGDPLDVMVMTHGRT
FTGCLIEVRPVGMLKMRDDKGLDHKILSVPINDPMYSHVRRLSDLPSHLPTEIEHFFSVYKELEGKAVESFGWYDFFTAE
QTIIEAMKAYDAANEEADEEDGKKKKKKDKKGKKDKKGHDAEVGETMASQDSAQMAFDGREEDIEEGHDETVA
>Mature_233_residues
MVNYKSLPSGQNPPKEVYAVIEVPQGERNKYEFDPDLCVFKLDRVLYASVHYPTGYGFIPRTLAEDGDPLDVMVMTHGRT
FTGCLIEVRPVGMLKMRDDKGLDHKILSVPINDPMYSHVRRLSDLPSHLPTEIEHFFSVYKELEGKAVESFGWYDFFTAE
QTIIEAMKAYDAANEEADEEDGKKKKKKDKKGKKDKKGHDAEVGETMASQDSAQMAFDGREEDIEEGHDETVA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=167, Percent_Identity=38.9221556886228, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 26415; Mature: 26415

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYKSLPSGQNPPKEVYAVIEVPQGERNKYEFDPDLCVFKLDRVLYASVHYPTGYGFIP
CCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCC
RTLAEDGDPLDVMVMTHGRTFTGCLIEVRPVGMLKMRDDKGLDHKILSVPINDPMYSHVR
HHHHCCCCCEEEEEEECCCEEEEEEEEEECCCEEEECCCCCCCCEEEEECCCCHHHHHHH
RLSDLPSHLPTEIEHFFSVYKELEGKAVESFGWYDFFTAEQTIIEAMKAYDAANEEADEE
HHHHCHHCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
DGKKKKKKDKKGKKDKKGHDAEVGETMASQDSAQMAFDGREEDIEEGHDETVA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MVNYKSLPSGQNPPKEVYAVIEVPQGERNKYEFDPDLCVFKLDRVLYASVHYPTGYGFIP
CCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCC
RTLAEDGDPLDVMVMTHGRTFTGCLIEVRPVGMLKMRDDKGLDHKILSVPINDPMYSHVR
HHHHCCCCCEEEEEEECCCEEEEEEEEEECCCEEEECCCCCCCCEEEEECCCCHHHHHHH
RLSDLPSHLPTEIEHFFSVYKELEGKAVESFGWYDFFTAEQTIIEAMKAYDAANEEADEE
HHHHCHHCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
DGKKKKKKDKKGKKDKKGHDAEVGETMASQDSAQMAFDGREEDIEEGHDETVA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]