Click here to switch to the map view.

The map label for this gene is yxiO [H]

Identifier: 193213931

GI number: 193213931

Start: 246803

End: 248083

Strand: Direct

Name: yxiO [H]

Synonym: Ctha_0212

Alternate gene names: 193213931

Gene position: 246803-248083 (Clockwise)

Preceding gene: 193213930

Following gene: 193213932

Centisome position: 7.49

GC content: 48.17

Gene sequence:

>1281_bases
ATGCCTTTGTCATCGGAAACGGCTGAGCCCGTTCCACTTCAGAACGAAGAACCTTACTCTAAACGAAATATTTTTGCCTG
GACGCTCTTCGATTTTGCGAACACGTCGTTCAGCGTCATGATTGTCACCTTTGTTTATCCCCTTTACTTTAAGAACATTA
TTTGCGCGGGGCACGCCATCGGCGATGCGCTTTGGGGCACCAATGTGAGCATTTCGATGCTTATTGGCGCCGTGGTTGCG
CCGGTGCTTGGTGCCGCCTCCGATTATTCCGGTCGGCGCAAGCGTTTCCTTTTGGCCTTCACTTTAATTTCCATTCTCTG
CACTTCGTTGATGTTTTTCACCTCAGCGGACATGATTCTCATCGGTTCAGTGCTCTTTATTTTGGCAAATGTCGGATTCG
AAGGCGGACTGGTTTTTTACGATGCTTATTTGCCGGAAATTACATCTAAGCGAAGCTACGGGCGCGTTTCCGGCTACGGC
TTTGCAATGGGCTATTTGGGCGCGCTCGTTACTTTAGCCGCTTCATTTCCGTTGATTATTGGCGGGTTTGAGCCGGAAAA
TTTGCTCAACATCCGATATAGTTTTTTGCTCGCGGCTGGGTTTTTCTTCTTTTTCTCGATTCCGCTTTTTCTTGCGTTGC
GCGATAAAAAACCCGCGCGCGCCGAACATATTTCGTTCTTGAAAGCTGGTTTTCGTGAAGTTCGTGCGACGCTTTCAAAC
ATCCGAAACTACCCCAACTTGGTTCGTTTCTTGACGGCGTTCTTCTTCTACAACGACGGCATTTTGACAATCATCGCTTT
CGCCTCGATTTATGCCGCCAACACGCTCAATTTTTCATTTCAAGAACTGGTTATTTTCTTCATCACCGTGCAAACCACCG
CCATTTTAGGCTCGGTGATTTTTGGCGTGATTACCGACAAAATCGGTGCAAAACGCACCATTGTAATTACGCTGCTCATT
TGGATTTTTGTGATTTTGCTCGCGTACTTTACCGACACAAAAGAGATGTTTTACATAGTGGGACTGTTTGCAGGCATTTC
AATGGGCGCGTCGCAGTCCGCTTCGCGCAGCTTGATGGCGCGGCTCACGCCGGCAGAGCATTCAGCCGAGTTTTTCGGCT
TTTATGACGGTTCGTTCGGCAAAGCATCGGCTATTGTGGGGCCTTGGATTTTTGGGCTTATTTCCACGCTTGCAGGCAGC
CAGCGCATCGCGATTCTTTCGTTGCTCCTTTTCTTCACCGTCGGCCTTTGGCTGATTTTAAAAGTTCGTACAGAAAAATG
A

Upstream 100 bases:

>100_bases
ATTTTCTTTGACGCGATTACAGGCGAAGAACTCGCCATAGATTATCCTGAACCTAAATGGTAGTTGCTCAAAAATACAGT
AAACCTTAAAACTCACATTC

Downstream 100 bases:

>100_bases
TGCGGCATCTCACAGAAACACATCGCAACATGCGTTTGAGAGAACGTTTCAAAACCTAACGCTCAAAAAAGCACACGAAC
GTTACTTGACGTTCTTCCGT

Product: major facilitator superfamily protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MPLSSETAEPVPLQNEEPYSKRNIFAWTLFDFANTSFSVMIVTFVYPLYFKNIICAGHAIGDALWGTNVSISMLIGAVVA
PVLGAASDYSGRRKRFLLAFTLISILCTSLMFFTSADMILIGSVLFILANVGFEGGLVFYDAYLPEITSKRSYGRVSGYG
FAMGYLGALVTLAASFPLIIGGFEPENLLNIRYSFLLAAGFFFFFSIPLFLALRDKKPARAEHISFLKAGFREVRATLSN
IRNYPNLVRFLTAFFFYNDGILTIIAFASIYAANTLNFSFQELVIFFITVQTTAILGSVIFGVITDKIGAKRTIVITLLI
WIFVILLAYFTDTKEMFYIVGLFAGISMGASQSASRSLMARLTPAEHSAEFFGFYDGSFGKASAIVGPWIFGLISTLAGS
QRIAILSLLLFFTVGLWLILKVRTEK

Sequences:

>Translated_426_residues
MPLSSETAEPVPLQNEEPYSKRNIFAWTLFDFANTSFSVMIVTFVYPLYFKNIICAGHAIGDALWGTNVSISMLIGAVVA
PVLGAASDYSGRRKRFLLAFTLISILCTSLMFFTSADMILIGSVLFILANVGFEGGLVFYDAYLPEITSKRSYGRVSGYG
FAMGYLGALVTLAASFPLIIGGFEPENLLNIRYSFLLAAGFFFFFSIPLFLALRDKKPARAEHISFLKAGFREVRATLSN
IRNYPNLVRFLTAFFFYNDGILTIIAFASIYAANTLNFSFQELVIFFITVQTTAILGSVIFGVITDKIGAKRTIVITLLI
WIFVILLAYFTDTKEMFYIVGLFAGISMGASQSASRSLMARLTPAEHSAEFFGFYDGSFGKASAIVGPWIFGLISTLAGS
QRIAILSLLLFFTVGLWLILKVRTEK
>Mature_425_residues
PLSSETAEPVPLQNEEPYSKRNIFAWTLFDFANTSFSVMIVTFVYPLYFKNIICAGHAIGDALWGTNVSISMLIGAVVAP
VLGAASDYSGRRKRFLLAFTLISILCTSLMFFTSADMILIGSVLFILANVGFEGGLVFYDAYLPEITSKRSYGRVSGYGF
AMGYLGALVTLAASFPLIIGGFEPENLLNIRYSFLLAAGFFFFFSIPLFLALRDKKPARAEHISFLKAGFREVRATLSNI
RNYPNLVRFLTAFFFYNDGILTIIAFASIYAANTLNFSFQELVIFFITVQTTAILGSVIFGVITDKIGAKRTIVITLLIW
IFVILLAYFTDTKEMFYIVGLFAGISMGASQSASRSLMARLTPAEHSAEFFGFYDGSFGKASAIVGPWIFGLISTLAGSQ
RIAILSLLLFFTVGLWLILKVRTEK

Specific function: Unknown

COG id: COG2270

COG function: function code R; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47023; Mature: 46892

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSSETAEPVPLQNEEPYSKRNIFAWTLFDFANTSFSVMIVTFVYPLYFKNIICAGHAI
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GDALWGTNVSISMLIGAVVAPVLGAASDYSGRRKRFLLAFTLISILCTSLMFFTSADMIL
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGSVLFILANVGFEGGLVFYDAYLPEITSKRSYGRVSGYGFAMGYLGALVTLAASFPLII
HHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
GGFEPENLLNIRYSFLLAAGFFFFFSIPLFLALRDKKPARAEHISFLKAGFREVRATLSN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRNYPNLVRFLTAFFFYNDGILTIIAFASIYAANTLNFSFQELVIFFITVQTTAILGSVI
HHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FGVITDKIGAKRTIVITLLIWIFVILLAYFTDTKEMFYIVGLFAGISMGASQSASRSLMA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RLTPAEHSAEFFGFYDGSFGKASAIVGPWIFGLISTLAGSQRIAILSLLLFFTVGLWLIL
HCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KVRTEK
EEECCC
>Mature Secondary Structure 
PLSSETAEPVPLQNEEPYSKRNIFAWTLFDFANTSFSVMIVTFVYPLYFKNIICAGHAI
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GDALWGTNVSISMLIGAVVAPVLGAASDYSGRRKRFLLAFTLISILCTSLMFFTSADMIL
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGSVLFILANVGFEGGLVFYDAYLPEITSKRSYGRVSGYGFAMGYLGALVTLAASFPLII
HHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
GGFEPENLLNIRYSFLLAAGFFFFFSIPLFLALRDKKPARAEHISFLKAGFREVRATLSN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRNYPNLVRFLTAFFFYNDGILTIIAFASIYAANTLNFSFQELVIFFITVQTTAILGSVI
HHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FGVITDKIGAKRTIVITLLIWIFVILLAYFTDTKEMFYIVGLFAGISMGASQSASRSLMA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RLTPAEHSAEFFGFYDGSFGKASAIVGPWIFGLISTLAGSQRIAILSLLLFFTVGLWLIL
HCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KVRTEK
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]