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The map label for this gene is galE [H]

Identifier: 193213768

GI number: 193213768

Start: 61814

End: 62803

Strand: Direct

Name: galE [H]

Synonym: Ctha_0049

Alternate gene names: 193213768

Gene position: 61814-62803 (Clockwise)

Preceding gene: 193213767

Following gene: 193213769

Centisome position: 1.88

GC content: 48.69

Gene sequence:

>990_bases
ATGACTGTTCTTATTACAGGCGGCGCGGGCTACATTGGCTCCCACGCAGTGCGCCGGCTTAAGCAAGCAGGCTACAAAAC
GTTGGTTTTAGATAATCTGGTTTATGGACATAGCGAGTTCGTGGAAGCTGACGAGCTGATCATCGGAGATTTGGAAAACA
CGAAATTGCTGAACCAAGTCTTTTCCAAGCATAAGATTCAGGCCGTGATGCACTTTGCCGCGTATGCTTATGTCGGCGAA
TCGGTACAAAATCCAGCAAAATATTACCGGAACAATGTTGCAAGCACGCTCAACTTGCTTGATGCGATGCTTGCGTATAA
AGTAAAAAAGTTCATATTTTCATCCACTTGCGCCACTTACGGCGAACCAGATGAAATTCCAATTACCGAAACTCACCCGC
AAAGACCGATTAATCCCTATGGCCAATCCAAATTGATGGTTGAGAAAATTTTGGATGATTATGACCATGCCTATGATTTG
CGCTCGGTGCGGCTTCGCTATTTCAACGCGGCAGGCGCTGACCCAGACGGCGGCATCGGCGAAGACCACGACCCGGAAAC
CCATCTCATCCCATTGGTTTTAGACGCCGCGCTGGAACGCCGCGCTCACATCTCCATGTTTGGAACAGATTACGACACGC
CCGATGGCACTTGCGTTCGCGATTATATCCACGTGACCGATTTAGCCGAAGCGCATGTGCTTGGCCTGAAATATCTTGAA
AATGGTGGGAAAACAGATTTCTTCAACTTAGGCAATGGCAACGGTTTTTCGGTTAAAGAGGTCATTGAAACCGCGCGAAA
AATCACAGGAAAAGAGATTCCCGCAAAAATAGCCCCTCGCCGCCCAGGCGACCCGGCAAGCTTAGTTGGAAGTTCGGAAA
AAATAAAATCAGCGTTAGGCTGGAAACCTCAATTTCCAGATTTGCCAGCCATCATCGAGACGGCATGGCAATGGCACAAA
ACCCGCTTTGGCCGGACTGCACAGACATAA

Upstream 100 bases:

>100_bases
AAGAAATAATATCGTTTGTAGCTTGAGCGGAATCCGTTATCTTTTCAAGAAGTTTTCAACAAATAAGGGCTCAACTAACA
AAAGCAATTCGGGGATTCCC

Downstream 100 bases:

>100_bases
TTTTTTATAAGTTCAAAAATATCAGAAGTTAGTTATGCAAATACCGGCGCGTAAACTTGAAATTGTTAAAGAACACGCGA
TTCAATCGTTTCCCGAAGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTVLITGGAGYIGSHAVRRLKQAGYKTLVLDNLVYGHSEFVEADELIIGDLENTKLLNQVFSKHKIQAVMHFAAYAYVGE
SVQNPAKYYRNNVASTLNLLDAMLAYKVKKFIFSSTCATYGEPDEIPITETHPQRPINPYGQSKLMVEKILDDYDHAYDL
RSVRLRYFNAAGADPDGGIGEDHDPETHLIPLVLDAALERRAHISMFGTDYDTPDGTCVRDYIHVTDLAEAHVLGLKYLE
NGGKTDFFNLGNGNGFSVKEVIETARKITGKEIPAKIAPRRPGDPASLVGSSEKIKSALGWKPQFPDLPAIIETAWQWHK
TRFGRTAQT

Sequences:

>Translated_329_residues
MTVLITGGAGYIGSHAVRRLKQAGYKTLVLDNLVYGHSEFVEADELIIGDLENTKLLNQVFSKHKIQAVMHFAAYAYVGE
SVQNPAKYYRNNVASTLNLLDAMLAYKVKKFIFSSTCATYGEPDEIPITETHPQRPINPYGQSKLMVEKILDDYDHAYDL
RSVRLRYFNAAGADPDGGIGEDHDPETHLIPLVLDAALERRAHISMFGTDYDTPDGTCVRDYIHVTDLAEAHVLGLKYLE
NGGKTDFFNLGNGNGFSVKEVIETARKITGKEIPAKIAPRRPGDPASLVGSSEKIKSALGWKPQFPDLPAIIETAWQWHK
TRFGRTAQT
>Mature_328_residues
TVLITGGAGYIGSHAVRRLKQAGYKTLVLDNLVYGHSEFVEADELIIGDLENTKLLNQVFSKHKIQAVMHFAAYAYVGES
VQNPAKYYRNNVASTLNLLDAMLAYKVKKFIFSSTCATYGEPDEIPITETHPQRPINPYGQSKLMVEKILDDYDHAYDLR
SVRLRYFNAAGADPDGGIGEDHDPETHLIPLVLDAALERRAHISMFGTDYDTPDGTCVRDYIHVTDLAEAHVLGLKYLEN
GGKTDFFNLGNGNGFSVKEVIETARKITGKEIPAKIAPRRPGDPASLVGSSEKIKSALGWKPQFPDLPAIIETAWQWHKT
RFGRTAQT

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=40.4692082111437, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=40.4692082111437, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=40.4692082111437, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI7657641, Length=337, Percent_Identity=28.486646884273, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI42516563, Length=319, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=41.6918429003021, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=30.0884955752212, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=28.7833827893175, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790049, Length=266, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788365, Length=339, Percent_Identity=27.7286135693215, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=38.9380530973451, Blast_Score=235, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=38.7096774193548, Blast_Score=234, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17568069, Length=335, Percent_Identity=27.7611940298507, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115532424, Length=347, Percent_Identity=27.3775216138329, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI133901786, Length=349, Percent_Identity=26.0744985673352, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539422, Length=349, Percent_Identity=26.0744985673352, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133901788, Length=349, Percent_Identity=26.0744985673352, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133901790, Length=349, Percent_Identity=26.0744985673352, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=25.0793650793651, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539424, Length=349, Percent_Identity=26.0744985673352, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=347, Percent_Identity=24.7838616714697, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=336, Percent_Identity=41.3690476190476, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=41.1242603550296, Blast_Score=237, Evalue=7e-63,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=27.2151898734177, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667531, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36512; Mature: 36381

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLITGGAGYIGSHAVRRLKQAGYKTLVLDNLVYGHSEFVEADELIIGDLENTKLLNQV
CEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHCCCHHEECCCCHHHHHHHH
FSKHKIQAVMHFAAYAYVGESVQNPAKYYRNNVASTLNLLDAMLAYKVKKFIFSSTCATY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEPDEIPITETHPQRPINPYGQSKLMVEKILDDYDHAYDLRSVRLRYFNAAGADPDGGIG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EDHDPETHLIPLVLDAALERRAHISMFGTDYDTPDGTCVRDYIHVTDLAEAHVLGLKYLE
CCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NGGKTDFFNLGNGNGFSVKEVIETARKITGKEIPAKIAPRRPGDPASLVGSSEKIKSALG
CCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHC
WKPQFPDLPAIIETAWQWHKTRFGRTAQT
CCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVLITGGAGYIGSHAVRRLKQAGYKTLVLDNLVYGHSEFVEADELIIGDLENTKLLNQV
EEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHCCHHHHCCCHHEECCCCHHHHHHHH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CCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]