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The map label for this gene is argS [H]

Identifier: 192291567

GI number: 192291567

Start: 3441046

End: 3442824

Strand: Reverse

Name: argS [H]

Synonym: Rpal_3194

Alternate gene names: 192291567

Gene position: 3442824-3441046 (Counterclockwise)

Preceding gene: 192291568

Following gene: 192291566

Centisome position: 59.94

GC content: 64.81

Gene sequence:

>1779_bases
ATGTCCACGCATCTTTTCGCCCGTCTCCTGTCGCGCGTACACGCGGTGTGCGCGGCGTTGATCGAAGAGGGCGCGCTGCC
CGCCGGGATCGACCTGTCGCGCATCGTGGTCGAGCCGCCGAAGGACGCCTCCCACGGCGACATGGCGACCAATGCCGCGA
TGGTGTTGGCCAAGGACGCCAAGGCCAAGCCGCGCGATCTCGCCGACAAGATCGCAGACAAACTGCGGGCCGAGGAGCTG
ATCGACCAAGTCGCGATCGCCGGGCCCGGCTTCATCAACCTGACGCTGAAGCCGGCGGTGTGGGCGGAGGCGCTGCGCGC
CGTGCTCGACGCCGGCGCCGGTTACGGCCGCAGCACCGTTGGCGGTGGTGAGAAGGTCAACGTCGAATACGTCTCGGCCA
ATCCGACCGGGCCGATGCATGTCGGTCACTGCCGCGGCGCGGTGTTCGGCGATGCGCTGGCCAATCTGCTCGACACCGCC
GGCTACGCCGTCACCCGCGAGTACTACATCAACGACGCTGGCGCCCAGGTCGATGTGCTGGCGCGCTCGGCGTTCCTGCG
CTACCGCGAGGCGCTCGGCGAGACGATCGGTGAGATTCCGGAAGGGCTGTATCCGGGCGACTACCTCAAGCCGGTCGGAG
AGGCGTTGAAGGCCGAGTACGGCGCGGCGCTCAATGACATGCCGGAAGCGCAGTGGCTGCCGACCGTCCGCGCCACCGCG
ATCGCGATGATGATGGAAGCGATCAAGGGCGACTTGGCGGCGCTGAACATCACCCACGAGGTGTTCTTCTCGGAGCGCTC
GCTGATCGAGGGCGGCCGCAACCGCGTCGCCGAGACCATCGAATTCCTTCGCGCCAAGGGCGACGTGTATCAGGGCCGTC
TGCCGCCGCCGAAGGGCGCGCCGGTGGAGGACTATGAGGATCGCGAACAGACGTTGTTCCGCGCTACCGCCTATGGCGAC
GACGTCGACCGGCCGCTGCTGAAGTCGGACGGCTCCTACACCTACTTCGCGTCCGACATCGCCTATCACAAGGTCAAGTT
CGACGCCGGCTTCGCCAACATGGTCGACGTCTGGGGCGCCGATCACGGCGGCTACATCAAGCGGATGCAGGCGGCGATCC
AGGCTGTGACGGCCGGCAAGGGCGCGCTCGACGTCAAGATCGTCCAGCTCGTCCGGCTGCTGCGCAACGGCGAGCCGGTG
AAGATGTCGAAGCGGGCAGGTGACTTCGTCACGTTGCGTGAAGTGGTGGATGAGGTCGGTTCCGACGCCGTCCGCTTCAT
GATGCTGTTCCGCAAGAACGACGCGGTGCTCGATTTCGATCTCGCCAAGGTGATCGAGCAGTCGAAAGACAATCCGGTGT
TCTACGTCCAGTACGGCCACGCGCGCGGCCACTCGATCTTCCGTAACGCGCGCGAGGTCGTTCCGGATCTGCCTGAGGAT
TCGAAGGCGCGGGCTGCGATGCTGCGGCAAGCGCCGCTGGAGCGTCTGAACGATCCGGCCGAGCTCGAACTATTGAAGCG
ACTTGCGCTCTATCCGCGTATCGTCGAAGCCGCCGCTCAGGCCCACGAGCCGCACAGAATCGCGTTTTATCTCAATGAGC
TCGCGAGCGAATTTCATGCGCTTTGGACGCATGGTCGCGATTTGCCTCATTTACGCTTCATTATCAATAATGATGCAGAG
ATAACCAGGGCGCGCTTGGCGATGGTCCAAGGCGTCGTCTCGGTTTTGGCCTCGGGGCTCGCCATTCTCGGCGTCACTGC
GCCGGACGAGATGCGATAG

Upstream 100 bases:

>100_bases
GCGGCTTTTTGACTCGACCCCGGATTTGCGTTAGGCGGCGCCCGGACCGGCCCGAAACGGCCGCTCCCATTTTCCCTTTT
CAGATATGGCCGAGCTCCCG

Downstream 100 bases:

>100_bases
GGGATCGGCCGTCAGATGGGGATCTGGAGCGGCTTGTGAGAGCGGCCGTGTCGTCTGCGAAGGCGCCTTGGGCAGCTTTC
CCGAATGGGACGCGACATCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSTHLFARLLSRVHAVCAALIEEGALPAGIDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLADKIADKLRAEEL
IDQVAIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSTVGGGEKVNVEYVSANPTGPMHVGHCRGAVFGDALANLLDTA
GYAVTREYYINDAGAQVDVLARSAFLRYREALGETIGEIPEGLYPGDYLKPVGEALKAEYGAALNDMPEAQWLPTVRATA
IAMMMEAIKGDLAALNITHEVFFSERSLIEGGRNRVAETIEFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRATAYGD
DVDRPLLKSDGSYTYFASDIAYHKVKFDAGFANMVDVWGADHGGYIKRMQAAIQAVTAGKGALDVKIVQLVRLLRNGEPV
KMSKRAGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAREVVPDLPED
SKARAAMLRQAPLERLNDPAELELLKRLALYPRIVEAAAQAHEPHRIAFYLNELASEFHALWTHGRDLPHLRFIINNDAE
ITRARLAMVQGVVSVLASGLAILGVTAPDEMR

Sequences:

>Translated_592_residues
MSTHLFARLLSRVHAVCAALIEEGALPAGIDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLADKIADKLRAEEL
IDQVAIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSTVGGGEKVNVEYVSANPTGPMHVGHCRGAVFGDALANLLDTA
GYAVTREYYINDAGAQVDVLARSAFLRYREALGETIGEIPEGLYPGDYLKPVGEALKAEYGAALNDMPEAQWLPTVRATA
IAMMMEAIKGDLAALNITHEVFFSERSLIEGGRNRVAETIEFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRATAYGD
DVDRPLLKSDGSYTYFASDIAYHKVKFDAGFANMVDVWGADHGGYIKRMQAAIQAVTAGKGALDVKIVQLVRLLRNGEPV
KMSKRAGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAREVVPDLPED
SKARAAMLRQAPLERLNDPAELELLKRLALYPRIVEAAAQAHEPHRIAFYLNELASEFHALWTHGRDLPHLRFIINNDAE
ITRARLAMVQGVVSVLASGLAILGVTAPDEMR
>Mature_591_residues
STHLFARLLSRVHAVCAALIEEGALPAGIDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLADKIADKLRAEELI
DQVAIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSTVGGGEKVNVEYVSANPTGPMHVGHCRGAVFGDALANLLDTAG
YAVTREYYINDAGAQVDVLARSAFLRYREALGETIGEIPEGLYPGDYLKPVGEALKAEYGAALNDMPEAQWLPTVRATAI
AMMMEAIKGDLAALNITHEVFFSERSLIEGGRNRVAETIEFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRATAYGDD
VDRPLLKSDGSYTYFASDIAYHKVKFDAGFANMVDVWGADHGGYIKRMQAAIQAVTAGKGALDVKIVQLVRLLRNGEPVK
MSKRAGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAREVVPDLPEDS
KARAAMLRQAPLERLNDPAELELLKRLALYPRIVEAAAQAHEPHRIAFYLNELASEFHALWTHGRDLPHLRFIINNDAEI
TRARLAMVQGVVSVLASGLAILGVTAPDEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=616, Percent_Identity=24.3506493506494, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1788184, Length=591, Percent_Identity=26.5651438240271, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71985061, Length=630, Percent_Identity=23.3333333333333, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=579, Percent_Identity=23.4887737478411, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=25.1748251748252, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI18859963, Length=618, Percent_Identity=23.6245954692557, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64638; Mature: 64506

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHLFARLLSRVHAVCAALIEEGALPAGIDLSRIVVEPPKDASHGDMATNAAMVLAKDA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHCHHEEEECCC
KAKPRDLADKIADKLRAEELIDQVAIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSTV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCC
GGGEKVNVEYVSANPTGPMHVGHCRGAVFGDALANLLDTAGYAVTREYYINDAGAQVDVL
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHEEEECCCCCHHHHH
ARSAFLRYREALGETIGEIPEGLYPGDYLKPVGEALKAEYGAALNDMPEAQWLPTVRATA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHH
IAMMMEAIKGDLAALNITHEVFFSERSLIEGGRNRVAETIEFLRAKGDVYQGRLPPPKGA
HHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PVEDYEDREQTLFRATAYGDDVDRPLLKSDGSYTYFASDIAYHKVKFDAGFANMVDVWGA
CCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHCC
DHGGYIKRMQAAIQAVTAGKGALDVKIVQLVRLLRNGEPVKMSKRAGDFVTLREVVDEVG
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHHHHHHHHC
SDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAREVVPDLPED
CHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
SKARAAMLRQAPLERLNDPAELELLKRLALYPRIVEAAAQAHEPHRIAFYLNELASEFHA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LWTHGRDLPHLRFIINNDAEITRARLAMVQGVVSVLASGLAILGVTAPDEMR
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
>Mature Secondary Structure 
STHLFARLLSRVHAVCAALIEEGALPAGIDLSRIVVEPPKDASHGDMATNAAMVLAKDA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHCHHEEEECCC
KAKPRDLADKIADKLRAEELIDQVAIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSTV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCC
GGGEKVNVEYVSANPTGPMHVGHCRGAVFGDALANLLDTAGYAVTREYYINDAGAQVDVL
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHEEEECCCCCHHHHH
ARSAFLRYREALGETIGEIPEGLYPGDYLKPVGEALKAEYGAALNDMPEAQWLPTVRATA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHH
IAMMMEAIKGDLAALNITHEVFFSERSLIEGGRNRVAETIEFLRAKGDVYQGRLPPPKGA
HHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PVEDYEDREQTLFRATAYGDDVDRPLLKSDGSYTYFASDIAYHKVKFDAGFANMVDVWGA
CCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCEEEEEEECCCHHHHHHHHCC
DHGGYIKRMQAAIQAVTAGKGALDVKIVQLVRLLRNGEPVKMSKRAGDFVTLREVVDEVG
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHHHHHHHHC
SDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAREVVPDLPED
CHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
SKARAAMLRQAPLERLNDPAELELLKRLALYPRIVEAAAQAHEPHRIAFYLNELASEFHA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LWTHGRDLPHLRFIINNDAEITRARLAMVQGVVSVLASGLAILGVTAPDEMR
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA