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The map label for this gene is yeiJ [C]

Identifier: 192290845

GI number: 192290845

Start: 2658009

End: 2659259

Strand: Reverse

Name: yeiJ [C]

Synonym: Rpal_2461

Alternate gene names: 192290845

Gene position: 2659259-2658009 (Counterclockwise)

Preceding gene: 192290848

Following gene: 192290844

Centisome position: 46.3

GC content: 66.51

Gene sequence:

>1251_bases
ATGCTTCAACTGCAATCCGGATTCGGCGTATTCGCGCTGCTGATGCTCGCGTGGGCGTTCGGCGAGAATCGCGACCGTGT
GTCGGTGCGGCAGGTCGCGATCGGGCTCGGCATCACGCTTTTGACCGCGGTGGCGATGCTGAAGCTGCCCGGCGCAGCCC
AGGCGTTCGGAGCAATCAATGATGCGGTCGGCGTGATCTCGGCGGCGAGCCGGGCCGGCACCTCGTTCGCGTTCGGGTAT
CTCGGCGGCGCGCCGGCACCGTTCGACATTAAGGCGCCGGGGGCCAATTTCATCCTCGCGTTTCAGGCGCTGCCAGTGGT
GCTGGTGATGAGCGTGCTGACCACGTTGTTGTTTTACTGGCGGATCCTGCCGCCGGTGGTGCGCGCCATGGCCTGGCTGC
TGAAGCGCACGCTCGGCGTCGGCGGCGCGGTCGGGCTCTCGACCGCCGCCAATGTGTTTCTCGGCATGGTCGAAGCGCCG
CTCTTCATCCGCCCTTATCTGGCGCAGCTCACCCGCAGCGAACTGTTCCTGGTGATGACCGGCGGCATGGCCGGCATCGC
CGGTACCGTGCTGGTGCTGTACGCAACGCTGCTGGCTCCGGTGCTACCCGACGCCGCCGCGCATTTCGTCATCGCATCGG
TGCTTGGCGCACCGGCCGCGATCCTGGTCAGCCTGATCATGGTGCCGGAGACCGAAGCGCGCGCCACCGGCGGCGAGCTC
GCCGACCCCGGTCAGATCGCGGTCAGCAGCATGGATGCGATCGTCAAGGGGACCGCGGCCGGCCTCGAACTGCTGCTCAA
CATCATCGCGATGCTGATCGTGCTGGTGGCGCTGGTGTATCTCGGCAACGCCGTGCTCGGCCTGCTGCCGCACGTCGGCG
GCGAGGCGATCACGCTGCAACGGCTGCTCGGTTATCTGATGGCGCCGGTGTGCTGGCTGCTCGGCCTGCCATGGGATCAG
GCGGTCACCGCCGGTTCGCTGATGGGGATCAAGACCGTCCTCAACGAACTGATCGCCTATGTCGAACTGGCGAAACTGCC
GGCCGATGCGCTCGACCCGCGCTCGAAGCTGATTATGCTGTACGCGATGTGCGGCTTCGCCAATTTCGGCAGCCTCGGCA
TCATGCTCGGCGGCCTCACCGCAATGGCCCCCGAGCGCCGCGAAGAGATCGCCGCACTCGGCCTGCGGTCGATCGTATCC
GGCACGCTCACCACCTGCCTGATGGGCGCGGTGGTAGGATTGATAAGCTGA

Upstream 100 bases:

>100_bases
GAAGCCGCGATGACGGCCAAGCCGCGGCGGGCCGCGCTTTAGTCGACTTGCCAGCGCGCCCTGCCCTGGCCTACCCATCG
GCTTCGGCTCGGGGGACGAC

Downstream 100 bases:

>100_bases
TCGCCGCGGACCGCCGGCTGCAGCAAACGGCACGCTTGATAGCAAAGCGCAACACAGCTGGATCGGCAATATTTCGAAAC
GCCTCCTGCGCGGCCGGGTT

Product: Na+ dependent nucleoside transporter domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MLQLQSGFGVFALLMLAWAFGENRDRVSVRQVAIGLGITLLTAVAMLKLPGAAQAFGAINDAVGVISAASRAGTSFAFGY
LGGAPAPFDIKAPGANFILAFQALPVVLVMSVLTTLLFYWRILPPVVRAMAWLLKRTLGVGGAVGLSTAANVFLGMVEAP
LFIRPYLAQLTRSELFLVMTGGMAGIAGTVLVLYATLLAPVLPDAAAHFVIASVLGAPAAILVSLIMVPETEARATGGEL
ADPGQIAVSSMDAIVKGTAAGLELLLNIIAMLIVLVALVYLGNAVLGLLPHVGGEAITLQRLLGYLMAPVCWLLGLPWDQ
AVTAGSLMGIKTVLNELIAYVELAKLPADALDPRSKLIMLYAMCGFANFGSLGIMLGGLTAMAPERREEIAALGLRSIVS
GTLTTCLMGAVVGLIS

Sequences:

>Translated_416_residues
MLQLQSGFGVFALLMLAWAFGENRDRVSVRQVAIGLGITLLTAVAMLKLPGAAQAFGAINDAVGVISAASRAGTSFAFGY
LGGAPAPFDIKAPGANFILAFQALPVVLVMSVLTTLLFYWRILPPVVRAMAWLLKRTLGVGGAVGLSTAANVFLGMVEAP
LFIRPYLAQLTRSELFLVMTGGMAGIAGTVLVLYATLLAPVLPDAAAHFVIASVLGAPAAILVSLIMVPETEARATGGEL
ADPGQIAVSSMDAIVKGTAAGLELLLNIIAMLIVLVALVYLGNAVLGLLPHVGGEAITLQRLLGYLMAPVCWLLGLPWDQ
AVTAGSLMGIKTVLNELIAYVELAKLPADALDPRSKLIMLYAMCGFANFGSLGIMLGGLTAMAPERREEIAALGLRSIVS
GTLTTCLMGAVVGLIS
>Mature_416_residues
MLQLQSGFGVFALLMLAWAFGENRDRVSVRQVAIGLGITLLTAVAMLKLPGAAQAFGAINDAVGVISAASRAGTSFAFGY
LGGAPAPFDIKAPGANFILAFQALPVVLVMSVLTTLLFYWRILPPVVRAMAWLLKRTLGVGGAVGLSTAANVFLGMVEAP
LFIRPYLAQLTRSELFLVMTGGMAGIAGTVLVLYATLLAPVLPDAAAHFVIASVLGAPAAILVSLIMVPETEARATGGEL
ADPGQIAVSSMDAIVKGTAAGLELLLNIIAMLIVLVALVYLGNAVLGLLPHVGGEAITLQRLLGYLMAPVCWLLGLPWDQ
AVTAGSLMGIKTVLNELIAYVELAKLPADALDPRSKLIMLYAMCGFANFGSLGIMLGGLTAMAPERREEIAALGLRSIVS
GTLTTCLMGAVVGLIS

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=432, Percent_Identity=31.25, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI11545853, Length=383, Percent_Identity=30.2872062663185, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI227116277, Length=424, Percent_Identity=29.2452830188679, Blast_Score=191, Evalue=9e-49,
Organism=Escherichia coli, GI1788485, Length=415, Percent_Identity=31.3253012048193, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1788488, Length=415, Percent_Identity=30.1204819277108, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1788737, Length=407, Percent_Identity=26.044226044226, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71991794, Length=408, Percent_Identity=31.1274509803922, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17560276, Length=415, Percent_Identity=30.1204819277108, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI25146537, Length=213, Percent_Identity=30.5164319248826, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45552517, Length=406, Percent_Identity=30.7881773399015, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19921868, Length=406, Percent_Identity=30.7881773399015, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI45552519, Length=406, Percent_Identity=30.7881773399015, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI281360430, Length=370, Percent_Identity=32.4324324324324, Blast_Score=178, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43054; Mature: 43054

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLQSGFGVFALLMLAWAFGENRDRVSVRQVAIGLGITLLTAVAMLKLPGAAQAFGAIN
CCEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DAVGVISAASRAGTSFAFGYLGGAPAPFDIKAPGANFILAFQALPVVLVMSVLTTLLFYW
HHHHHHHHHHHCCCCEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RILPPVVRAMAWLLKRTLGVGGAVGLSTAANVFLGMVEAPLFIRPYLAQLTRSELFLVMT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEE
GGMAGIAGTVLVLYATLLAPVLPDAAAHFVIASVLGAPAAILVSLIMVPETEARATGGEL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCCC
ADPGQIAVSSMDAIVKGTAAGLELLLNIIAMLIVLVALVYLGNAVLGLLPHVGGEAITLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RLLGYLMAPVCWLLGLPWDQAVTAGSLMGIKTVLNELIAYVELAKLPADALDPRSKLIML
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
YAMCGFANFGSLGIMLGGLTAMAPERREEIAALGLRSIVSGTLTTCLMGAVVGLIS
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQLQSGFGVFALLMLAWAFGENRDRVSVRQVAIGLGITLLTAVAMLKLPGAAQAFGAIN
CCEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DAVGVISAASRAGTSFAFGYLGGAPAPFDIKAPGANFILAFQALPVVLVMSVLTTLLFYW
HHHHHHHHHHHCCCCEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RILPPVVRAMAWLLKRTLGVGGAVGLSTAANVFLGMVEAPLFIRPYLAQLTRSELFLVMT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEE
GGMAGIAGTVLVLYATLLAPVLPDAAAHFVIASVLGAPAAILVSLIMVPETEARATGGEL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCCCCC
ADPGQIAVSSMDAIVKGTAAGLELLLNIIAMLIVLVALVYLGNAVLGLLPHVGGEAITLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RLLGYLMAPVCWLLGLPWDQAVTAGSLMGIKTVLNELIAYVELAKLPADALDPRSKLIML
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
YAMCGFANFGSLGIMLGGLTAMAPERREEIAALGLRSIVSGTLTTCLMGAVVGLIS
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]