| Definition | Rhodopseudomonas palustris TIE-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011004 |
| Length | 5,744,041 |
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The map label for this gene is fabG [C]
Identifier: 192290837
GI number: 192290837
Start: 2647381
End: 2648130
Strand: Reverse
Name: fabG [C]
Synonym: Rpal_2453
Alternate gene names: 192290837
Gene position: 2648130-2647381 (Counterclockwise)
Preceding gene: 192290840
Following gene: 192290836
Centisome position: 46.1
GC content: 65.2
Gene sequence:
>750_bases ATGACCAAGACACTGCAAGGCAAAGTGGCGCTGGTGACCGGCGCATCGAAGGGCATCGGCGCGGAGATCGCGCTGAAGCT CGCGGCCGAAGGCGCCGCGGTCGCCGTGAACTACGCCTCCAGCAAACAGGGCGCCGACGACGTCGTGGACAAGATCACCG CGCAAGGCGGCAAAGCGATCGCGGTCGGCGGCAGCGTCGCCGATCCCAAGGAGGCGCAGGCCATCGTCGATGCGACCGTC GCAGCGTTCGGTCCGATCGACGTGTTGGTCAACAATGCCGGCGTGTATGAATTCGGCGCGCTCGATGACATCACGCCGGA GCACTTCCATCGCCAATTCGACGTCAACGTGCTCGGGTTGCTGCTGGTGACGCAAGCGGCCGCGCGGCAGTTCAACGACG GTGGCAGCGTCGTCAATATCTCATCCGGCGTTTCGACGATCGCGATGCCAAACACCGCGGTGTACGGCGCCACCAAGGCG TCGGTCGATCTGATCACGGCGGTGCTGGCGAAAGAACTGGCGCCGCGCAAGATCCGCGTCAACGCGGTCAACCCCGGCAT GGTGGTCACCGAAGGCGTCAAGTCTGCCGGCTTCCATGACGGCGAGATGCGAAAGCAGGTCGAAGCGATCACCCCGCTCG GCCGCATCGGCGAGGCTGCCGAGATCGCTTCGGTCGTCGCCTTCCTCGCCTCCGACGGCGCGTCTTACGTGACGGGTGAG ACGCTGCATGTCACCGGCGGGCTCAAGTAA
Upstream 100 bases:
>100_bases GGCGCCCCCTTGACCTGGTTCAATAGTCCCATATTTCCGAACTATTGAACCAATGGCCCCGTCAGCGGTGGCCGGACCTC CGATCAGGGACAGAACGATC
Downstream 100 bases:
>100_bases GCGCGGCTGCGCTCAAAGCTCCGGCGGCGGCGCCGGAGCCTTTCCCGCCGCACGGTGTTGCTCCGAGTTGTGTCGGCTGG CGCACCGATCTGCGTCGAGG
Product: short-chain dehydrogenase/reductase SDR
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: ORFC [H]
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MTKTLQGKVALVTGASKGIGAEIALKLAAEGAAVAVNYASSKQGADDVVDKITAQGGKAIAVGGSVADPKEAQAIVDATV AAFGPIDVLVNNAGVYEFGALDDITPEHFHRQFDVNVLGLLLVTQAAARQFNDGGSVVNISSGVSTIAMPNTAVYGATKA SVDLITAVLAKELAPRKIRVNAVNPGMVVTEGVKSAGFHDGEMRKQVEAITPLGRIGEAAEIASVVAFLASDGASYVTGE TLHVTGGLK
Sequences:
>Translated_249_residues MTKTLQGKVALVTGASKGIGAEIALKLAAEGAAVAVNYASSKQGADDVVDKITAQGGKAIAVGGSVADPKEAQAIVDATV AAFGPIDVLVNNAGVYEFGALDDITPEHFHRQFDVNVLGLLLVTQAAARQFNDGGSVVNISSGVSTIAMPNTAVYGATKA SVDLITAVLAKELAPRKIRVNAVNPGMVVTEGVKSAGFHDGEMRKQVEAITPLGRIGEAAEIASVVAFLASDGASYVTGE TLHVTGGLK >Mature_248_residues TKTLQGKVALVTGASKGIGAEIALKLAAEGAAVAVNYASSKQGADDVVDKITAQGGKAIAVGGSVADPKEAQAIVDATVA AFGPIDVLVNNAGVYEFGALDDITPEHFHRQFDVNVLGLLLVTQAAARQFNDGGSVVNISSGVSTIAMPNTAVYGATKAS VDLITAVLAKELAPRKIRVNAVNPGMVVTEGVKSAGFHDGEMRKQVEAITPLGRIGEAAEIASVVAFLASDGASYVTGET LHVTGGLK
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=36.1111111111111, Blast_Score=132, Evalue=3e-31, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=36.6533864541833, Blast_Score=131, Evalue=7e-31, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=35.2226720647773, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=33.969465648855, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=32.421875, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=33.469387755102, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=31.6, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI126723191, Length=214, Percent_Identity=34.5794392523364, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=31.4432989690722, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=30.6772908366534, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4503301, Length=252, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI32455239, Length=185, Percent_Identity=33.5135135135135, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI5031765, Length=185, Percent_Identity=33.5135135135135, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=33.5078534031414, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI109715829, Length=226, Percent_Identity=27.8761061946903, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=31.1557788944724, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=25.4752851711027, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=39.2712550607287, Blast_Score=147, Evalue=8e-37, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=37.3983739837398, Blast_Score=147, Evalue=9e-37, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=35.2459016393443, Blast_Score=141, Evalue=3e-35, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=35.9183673469388, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.8709677419355, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=32.3886639676113, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=30.9236947791165, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.5238095238095, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=34.2857142857143, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=31.640625, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.8617886178862, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787545, Length=256, Percent_Identity=30.46875, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=30.1158301158301, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=26.6932270916335, Blast_Score=71, Evalue=8e-14, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=39.344262295082, Blast_Score=146, Evalue=1e-35, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=37.5, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=33.203125, Blast_Score=124, Evalue=6e-29, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=33.2, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=34.5381526104418, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=36.4705882352941, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=33.5907335907336, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=35.6275303643725, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=30.9963099630996, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=32.4626865671642, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=32.183908045977, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=34.4827586206897, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=31.7829457364341, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=31.5175097276265, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=30.5220883534137, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=31.0861423220974, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=31.5175097276265, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=32.6923076923077, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=31.7829457364341, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=33.0798479087452, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=30.0395256916996, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=30.1158301158301, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=30.8550185873606, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=32.7067669172932, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561272, Length=252, Percent_Identity=32.9365079365079, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=30.9433962264151, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=27.4809160305344, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=28.6290322580645, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17568967, Length=225, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17555612, Length=253, Percent_Identity=32.4110671936759, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71997402, Length=162, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17558628, Length=194, Percent_Identity=32.9896907216495, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71997099, Length=208, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=28.4, Blast_Score=84, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=31.0483870967742, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=30.3191489361702, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=40.6374501992032, Blast_Score=156, Evalue=1e-38, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=42.1686746987952, Blast_Score=150, Evalue=7e-37, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=38.1526104417671, Blast_Score=149, Evalue=2e-36, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=36.9047619047619, Blast_Score=137, Evalue=7e-33, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=35.3413654618474, Blast_Score=121, Evalue=4e-28, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=36.6935483870968, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=37.1541501976285, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=31.6831683168317, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24640492, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI18859837, Length=247, Percent_Identity=29.9595141700405, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=30.3664921465969, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=28, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI281364892, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=30.3664921465969, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24641388, Length=208, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=26.2548262548263, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24584752, Length=190, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 25225; Mature: 25094
Theoretical pI: Translated: 5.30; Mature: 5.30
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKTLQGKVALVTGASKGIGAEIALKLAAEGAAVAVNYASSKQGADDVVDKITAQGGKAI CCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE AVGGSVADPKEAQAIVDATVAAFGPIDVLVNNAGVYEFGALDDITPEHFHRQFDVNVLGL EECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHHHHHCCCHHHHHH LLVTQAAARQFNDGGSVVNISSGVSTIAMPNTAVYGATKASVDLITAVLAKELAPRKIRV HHHHHHHHHHCCCCCCEEEECCCCEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCEEEE NAVNPGMVVTEGVKSAGFHDGEMRKQVEAITPLGRIGEAAEIASVVAFLASDGASYVTGE EEECCCEEEECCHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCEECCC TLHVTGGLK EEEECCCCC >Mature Secondary Structure TKTLQGKVALVTGASKGIGAEIALKLAAEGAAVAVNYASSKQGADDVVDKITAQGGKAI CCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE AVGGSVADPKEAQAIVDATVAAFGPIDVLVNNAGVYEFGALDDITPEHFHRQFDVNVLGL EECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHHHHHCCCHHHHHH LLVTQAAARQFNDGGSVVNISSGVSTIAMPNTAVYGATKASVDLITAVLAKELAPRKIRV HHHHHHHHHHCCCCCCEEEECCCCEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCEEEE NAVNPGMVVTEGVKSAGFHDGEMRKQVEAITPLGRIGEAAEIASVVAFLASDGASYVTGE EEECCCEEEECCHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCEECCC TLHVTGGLK EEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8868443 [H]