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The map label for this gene is cobL [H]

Identifier: 192290760

GI number: 192290760

Start: 2560384

End: 2561607

Strand: Reverse

Name: cobL [H]

Synonym: Rpal_2376

Alternate gene names: 192290760

Gene position: 2561607-2560384 (Counterclockwise)

Preceding gene: 192290762

Following gene: 192290759

Centisome position: 44.6

GC content: 71.24

Gene sequence:

>1224_bases
ATGATCAGTAGCGATGACACAGCGCAGCCCTGGCTGTCCATCGTCGGAATCGGCGAGGACGGTCTCGACGGGATATCGGC
CCGCGCGCGGGCACTCCTGGACGCAGCCGAGCTGGTCGTTGGCGGTGATCGCCACCTCGCCCTCGTCGCCGCTCTGCACA
AGCCCTCCTTGCCGTGGCGCGTGCCGTTCGCAGCCTCGTTGCCCAACGTGTTGGCGCGGCGCGGCCGCCGCGTCGTCGTG
CTGTGCTCCGGCGACCCGTTCTGGCACGGCGCCGGCGCGGTGCTGGCCGATCACCTCGCGGCGAACGAATGGACCGCGGT
CCCGGCGCCATCGACCTTTGCTTGGGCGGCGGCGCGGATCGGCTGGCGCCTGGAAGACACAGCGACGCTCGGCCTGCATG
CACGGCCGGTTGCAACGCTGCGCCCGCATCTCCGTCCCCAGGCGCGGCTGATCGTGCTGGTGCGCGATGGTGCAGCCGTG
GTCGAAATCGCCGCGTATCTGGCGGCGAATGGCTTCGGCGCATCCGAGCTCACCGTGCTCGAAGCGCTCGGCGGCCCGCG
CGAGCGCGTGCGGCGGACCACCGCGTCGATCTTCGCCTTCCCCGACGTCACCGCGCCGGTCGCACTCGGCATCGCCGTCG
TTGCAGAGCCAAATGCCATCATTATGCCGTGCATCAGCGGCCTGCCGGATGAGCTGTTTCAGCACGACGGCCAGCTCACC
AAGCGCGAGATCCGCGCCGTCACGCTGTCGACGCTGGCGCCGCGCGGACATGAGCTGCTCTGGGACATAGGCGCCGGTGC
CGGCTCGATCGGGATCGAATGGCTGCTGGCGGCGCGCAGCAATCACGCGATCGGGATCGAGACGCGGCCCGACCGGCTCG
CCACCGCGCGCGCCAATGCCGAGGCGCTCGGCGTGCCACAATTCGATCTGCGGCTCGGCTCGGCGCCCGACGCGCTCGCC
GGACTGCCCACGCCGAACGCGGTGTTCATCGGCGGCGGCGCCGGTCGTCCAGGCGTGATGGATGCAGTGTGGCAGGCGCT
GCCCGCCGGCGGCCGGCTGGTCGTGAATGCGGTGACGCTGGAGACCGAAGCGCTGCTGATCGACTGGCATCACCGCCACG
GCGGCGAGCTGCTGCGGCTCGGCGTCGAGCGCGCCTCCCCGGTCGGCGGCCTCACCGGATGGCGCGCGGCGATGCCGGTG
GTGCAATGGAGCGTCCACAAATGA

Upstream 100 bases:

>100_bases
GTCGATGGCCGGCTCGGCGGCGACGGTCCGTGCCAGCGCCGAGGCATCGGCGGTGCCGCCCAGGATCAATACGCGCGAGC
GATGCGATGAAGGGAGCGTC

Downstream 100 bases:

>100_bases
CCACGGTCGTGATCGGCGTCGGCTTTCGTTCCGCCGCATCCGCGTCTTCGATCATCGACGTGATCGAGACCGCGCGCCGC
GCCGTCGCCCCGCATCAACT

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MISSDDTAQPWLSIVGIGEDGLDGISARARALLDAAELVVGGDRHLALVAALHKPSLPWRVPFAASLPNVLARRGRRVVV
LCSGDPFWHGAGAVLADHLAANEWTAVPAPSTFAWAAARIGWRLEDTATLGLHARPVATLRPHLRPQARLIVLVRDGAAV
VEIAAYLAANGFGASELTVLEALGGPRERVRRTTASIFAFPDVTAPVALGIAVVAEPNAIIMPCISGLPDELFQHDGQLT
KREIRAVTLSTLAPRGHELLWDIGAGAGSIGIEWLLAARSNHAIGIETRPDRLATARANAEALGVPQFDLRLGSAPDALA
GLPTPNAVFIGGGAGRPGVMDAVWQALPAGGRLVVNAVTLETEALLIDWHHRHGGELLRLGVERASPVGGLTGWRAAMPV
VQWSVHK

Sequences:

>Translated_407_residues
MISSDDTAQPWLSIVGIGEDGLDGISARARALLDAAELVVGGDRHLALVAALHKPSLPWRVPFAASLPNVLARRGRRVVV
LCSGDPFWHGAGAVLADHLAANEWTAVPAPSTFAWAAARIGWRLEDTATLGLHARPVATLRPHLRPQARLIVLVRDGAAV
VEIAAYLAANGFGASELTVLEALGGPRERVRRTTASIFAFPDVTAPVALGIAVVAEPNAIIMPCISGLPDELFQHDGQLT
KREIRAVTLSTLAPRGHELLWDIGAGAGSIGIEWLLAARSNHAIGIETRPDRLATARANAEALGVPQFDLRLGSAPDALA
GLPTPNAVFIGGGAGRPGVMDAVWQALPAGGRLVVNAVTLETEALLIDWHHRHGGELLRLGVERASPVGGLTGWRAAMPV
VQWSVHK
>Mature_407_residues
MISSDDTAQPWLSIVGIGEDGLDGISARARALLDAAELVVGGDRHLALVAALHKPSLPWRVPFAASLPNVLARRGRRVVV
LCSGDPFWHGAGAVLADHLAANEWTAVPAPSTFAWAAARIGWRLEDTATLGLHARPVATLRPHLRPQARLIVLVRDGAAV
VEIAAYLAANGFGASELTVLEALGGPRERVRRTTASIFAFPDVTAPVALGIAVVAEPNAIIMPCISGLPDELFQHDGQLT
KREIRAVTLSTLAPRGHELLWDIGAGAGSIGIEWLLAARSNHAIGIETRPDRLATARANAEALGVPQFDLRLGSAPDALA
GLPTPNAVFIGGGAGRPGVMDAVWQALPAGGRLVVNAVTLETEALLIDWHHRHGGELLRLGVERASPVGGLTGWRAAMPV
VQWSVHK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42816; Mature: 42816

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSDDTAQPWLSIVGIGEDGLDGISARARALLDAAELVVGGDRHLALVAALHKPSLPWR
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCEE
VPFAASLPNVLARRGRRVVVLCSGDPFWHGAGAVLADHLAANEWTAVPAPSTFAWAAARI
CCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
GWRLEDTATLGLHARPVATLRPHLRPQARLIVLVRDGAAVVEIAAYLAANGFGASELTVL
CEEEECCEEECEECCCHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHH
EALGGPRERVRRTTASIFAFPDVTAPVALGIAVVAEPNAIIMPCISGLPDELFQHDGQLT
HHCCCHHHHHHHHHHHEEECCCCCCHHHHCEEEEECCCEEEEEHHCCCCHHHHHCCCCCC
KREIRAVTLSTLAPRGHELLWDIGAGAGSIGIEWLLAARSNHAIGIETRPDRLATARANA
HHHHHEEEEHHCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEECCCCCHHHECCCCC
EALGVPQFDLRLGSAPDALAGLPTPNAVFIGGGAGRPGVMDAVWQALPAGGRLVVNAVTL
CCCCCCHHEEEECCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEE
ETEALLIDWHHRHGGELLRLGVERASPVGGLTGWRAAMPVVQWSVHK
EEEEEEEEEECCCCCCEEEEEHHHCCCCCCCCCHHHHCCHHEEECCC
>Mature Secondary Structure
MISSDDTAQPWLSIVGIGEDGLDGISARARALLDAAELVVGGDRHLALVAALHKPSLPWR
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCEE
VPFAASLPNVLARRGRRVVVLCSGDPFWHGAGAVLADHLAANEWTAVPAPSTFAWAAARI
CCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
GWRLEDTATLGLHARPVATLRPHLRPQARLIVLVRDGAAVVEIAAYLAANGFGASELTVL
CEEEECCEEECEECCCHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHH
EALGGPRERVRRTTASIFAFPDVTAPVALGIAVVAEPNAIIMPCISGLPDELFQHDGQLT
HHCCCHHHHHHHHHHHEEECCCCCCHHHHCEEEEECCCEEEEEHHCCCCHHHHHCCCCCC
KREIRAVTLSTLAPRGHELLWDIGAGAGSIGIEWLLAARSNHAIGIETRPDRLATARANA
HHHHHEEEEHHCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEECCCCCHHHECCCCC
EALGVPQFDLRLGSAPDALAGLPTPNAVFIGGGAGRPGVMDAVWQALPAGGRLVVNAVTL
CCCCCCHHEEEECCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEE
ETEALLIDWHHRHGGELLRLGVERASPVGGLTGWRAAMPVVQWSVHK
EEEEEEEEEECCCCCCEEEEEHHHCCCCCCCCCHHHHCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]