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The map label for this gene is fnrL [H]

Identifier: 192290752

GI number: 192290752

Start: 2552828

End: 2553595

Strand: Reverse

Name: fnrL [H]

Synonym: Rpal_2367

Alternate gene names: 192290752

Gene position: 2553595-2552828 (Counterclockwise)

Preceding gene: 192290754

Following gene: 192290751

Centisome position: 44.46

GC content: 63.8

Gene sequence:

>768_bases
ATGGTTCACCCGTTCCTGCGCAAGCTTCGGCACGGAGCCCGGCTGACAAAGGACAGCGAGGAGATTCTCCTTCGTCTCAC
CCAGTCGAGCCGCTGCATCGGCGCCCGGGAGGATCTCGTGCCGGTCGGCGGACAACCGCACTATCTGCCGCTTCTGGTCG
AGGGCTGGGCCTGCCGCTATACCACGCTGGAGAACGGTCGCCGCCAGATCATCTCCCTGTTCCTGCCAGGCGACCTGTGC
GAGCCATTCGGCGCACTTCCCCGCTTCATGGACCATCCGATTGGAACCCTCACGCCTGCGGTGATCGCGCGGGTGCGGAC
GGATGCGGTCCGCAGCGCGGCACAGCTCAGTCCACGGATCGAGGAAGCGCTGTGGTGGGACTTGCTGGTCGCCTCCGCGA
TCGAGCGCGAGCACCTCGTCAGCCTCGGACGGCGAACCGCGACCGAACGGCTCGGACACCTGTTTTGCGAGCTTCATCTG
CGGCTCGGATTGGTCGGCCTCGTCGACGAGGACGAACTGTCCTACGAAATGCCGATCACGCAGGCCGACCTCGGCGATCT
GCTTGGAATGTCGATGGTACACATCAACCGCTCGCTGCAAGAGCTGAGACGGACGGGCATGATTTCGCTGCGCGGTCGCC
GTTTGACGATTCACAACCTCGAAGGACTGCGCGAATTGTCGTTCTTCGATGCAGGATATCTGCACCTGTTCGGCCCGCTC
TCGCTGCTGAACACCGACGGCTCTGACCTCGGAACGACCACCCGGTGA

Upstream 100 bases:

>100_bases
ATGTTTTGCATTCGTTCGACGTGGACGTGTTCTTTGTGCACACTGTCTCGGCGGAGATGATCCCGCGTCGCCCGATGAAG
CCAATCATAAAGGCGTACCG

Downstream 100 bases:

>100_bases
CCCATGCCGACCGATGACACCAACAGCCGGATAGCCGAACTCGAGGCCGACAATCGCCGCCTGCGGCAACTGCTCGACAA
GCGTGATGCCCCCGGCGAGC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVHPFLRKLRHGARLTKDSEEILLRLTQSSRCIGAREDLVPVGGQPHYLPLLVEGWACRYTTLENGRRQIISLFLPGDLC
EPFGALPRFMDHPIGTLTPAVIARVRTDAVRSAAQLSPRIEEALWWDLLVASAIEREHLVSLGRRTATERLGHLFCELHL
RLGLVGLVDEDELSYEMPITQADLGDLLGMSMVHINRSLQELRRTGMISLRGRRLTIHNLEGLRELSFFDAGYLHLFGPL
SLLNTDGSDLGTTTR

Sequences:

>Translated_255_residues
MVHPFLRKLRHGARLTKDSEEILLRLTQSSRCIGAREDLVPVGGQPHYLPLLVEGWACRYTTLENGRRQIISLFLPGDLC
EPFGALPRFMDHPIGTLTPAVIARVRTDAVRSAAQLSPRIEEALWWDLLVASAIEREHLVSLGRRTATERLGHLFCELHL
RLGLVGLVDEDELSYEMPITQADLGDLLGMSMVHINRSLQELRRTGMISLRGRRLTIHNLEGLRELSFFDAGYLHLFGPL
SLLNTDGSDLGTTTR
>Mature_255_residues
MVHPFLRKLRHGARLTKDSEEILLRLTQSSRCIGAREDLVPVGGQPHYLPLLVEGWACRYTTLENGRRQIISLFLPGDLC
EPFGALPRFMDHPIGTLTPAVIARVRTDAVRSAAQLSPRIEEALWWDLLVASAIEREHLVSLGRRTATERLGHLFCELHL
RLGLVGLVDEDELSYEMPITQADLGDLLGMSMVHINRSLQELRRTGMISLRGRRLTIHNLEGLRELSFFDAGYLHLFGPL
SLLNTDGSDLGTTTR

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28661; Mature: 28661

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHPFLRKLRHGARLTKDSEEILLRLTQSSRCIGAREDLVPVGGQPHYLPLLVEGWACRY
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCEEEE
TTLENGRRQIISLFLPGDLCEPFGALPRFMDHPIGTLTPAVIARVRTDAVRSAAQLSPRI
HHHHCCHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
EEALWWDLLVASAIEREHLVSLGRRTATERLGHLFCELHLRLGLVGLVDEDELSYEMPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEECCCC
QADLGDLLGMSMVHINRSLQELRRTGMISLRGRRLTIHNLEGLRELSFFDAGYLHLFGPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECHHHHHHHHHHCCCHHHHHCCH
SLLNTDGSDLGTTTR
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MVHPFLRKLRHGARLTKDSEEILLRLTQSSRCIGAREDLVPVGGQPHYLPLLVEGWACRY
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCEEEE
TTLENGRRQIISLFLPGDLCEPFGALPRFMDHPIGTLTPAVIARVRTDAVRSAAQLSPRI
HHHHCCHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
EEALWWDLLVASAIEREHLVSLGRRTATERLGHLFCELHLRLGLVGLVDEDELSYEMPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEECCCC
QADLGDLLGMSMVHINRSLQELRRTGMISLRGRRLTIHNLEGLRELSFFDAGYLHLFGPL
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECHHHHHHHHHHCCCHHHHHCCH
SLLNTDGSDLGTTTR
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]