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The map label for this gene is serB [C]

Identifier: 192290631

GI number: 192290631

Start: 2430730

End: 2431623

Strand: Reverse

Name: serB [C]

Synonym: Rpal_2240

Alternate gene names: 192290631

Gene position: 2431623-2430730 (Counterclockwise)

Preceding gene: 192290635

Following gene: 192290629

Centisome position: 42.33

GC content: 67.23

Gene sequence:

>894_bases
ATGTCGCTCGTCGCCACGCTCATCTGCAATCCGAACAATCCCGCGCTGGATTCGACCGTGATCGAGGGGGCGCGTGCGGT
GCTGCCCCAGCCCAATGAAGCAGTCTGGCTGCACGACGAGATCGCCGCCGACATCTTCTTTGCCAGCACCGAGGATCCCC
TGGTGCTTGCCGACCGGCTCCGCGCCGCCCGCGGCGACCTGCCGGTCGATGTCGTGGTGCAGCCTGCTGCGACCCGGCGC
AAGAAGCTTTTTCTCGCCGACATGGATTCGACCATGATCGGCCAGGAATGCATCGACGAGCTGGCCGGCTTCGTCGGGCT
GAAGGACCATGTCGCTGCGATCACCGAGCGGGCGATGCGCGGCGAAATCGAATTCGAGCCGGCGCTGCGCGAGCGCGTCG
CGCTGCTCAAGGGCCTGCCGCTCGACGTGATCGGCCAGGTGCTCGATACCCGGATCACGCTGACGCCGGGCGGCCGCGCG
GTGGTGCAGACGATGCGCGCCAATGGCGCCTACACCTGCCTTGTGTCCGGCGGCTTCACCCAGTTCACCCATGTGGTGGC
CGAACGGCTCGGCTTCGCCGAACATCGCGCCAACGAACTCCTGAGCGAGGACGGCAAGCTGACCGGCACCGTCGCCGAGC
CGATCCTCGGCCGCGACGCCAAGCTGGCGACACTGCTGGAGCTGCGCGAAGCCGACGATCTCGACGCAATCGACACACTG
GTGGTCGGCGATGGCGCCAACGATCTCGGCATGATCCAAGCCGCGGGTCTCGGGATCGCGTATCACGCCAAGCCTGCGGT
CGCCGCAGCGGCCCACGGCCGCATCGATTTCGGCGACCTCACTGCCCTGCTCTATGCGCAGGGCTATCGGCGCGACGAAT
TCGTCGCCGACTGA

Upstream 100 bases:

>100_bases
CGCCAGCTTCAGTGCCAAGGCCGACTTGCCGCTGGCGGTCGGCCCTGCGATAAGCACGGCCGCCGGCCGCCGGCCGTGCC
GTTCCGGACCTTCCGCTGTC

Downstream 100 bases:

>100_bases
TCCCTTCCCTGTCTCGGTCTCAGGCTAACGCAGCAGCTCCCGCCGATAGTGCTCGCGCAGGTCGGCCAGCACGATTCCCG
ACGCCATCATCACCGCGTGG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSLVATLICNPNNPALDSTVIEGARAVLPQPNEAVWLHDEIAADIFFASTEDPLVLADRLRAARGDLPVDVVVQPAATRR
KKLFLADMDSTMIGQECIDELAGFVGLKDHVAAITERAMRGEIEFEPALRERVALLKGLPLDVIGQVLDTRITLTPGGRA
VVQTMRANGAYTCLVSGGFTQFTHVVAERLGFAEHRANELLSEDGKLTGTVAEPILGRDAKLATLLELREADDLDAIDTL
VVGDGANDLGMIQAAGLGIAYHAKPAVAAAAHGRIDFGDLTALLYAQGYRRDEFVAD

Sequences:

>Translated_297_residues
MSLVATLICNPNNPALDSTVIEGARAVLPQPNEAVWLHDEIAADIFFASTEDPLVLADRLRAARGDLPVDVVVQPAATRR
KKLFLADMDSTMIGQECIDELAGFVGLKDHVAAITERAMRGEIEFEPALRERVALLKGLPLDVIGQVLDTRITLTPGGRA
VVQTMRANGAYTCLVSGGFTQFTHVVAERLGFAEHRANELLSEDGKLTGTVAEPILGRDAKLATLLELREADDLDAIDTL
VVGDGANDLGMIQAAGLGIAYHAKPAVAAAAHGRIDFGDLTALLYAQGYRRDEFVAD
>Mature_296_residues
SLVATLICNPNNPALDSTVIEGARAVLPQPNEAVWLHDEIAADIFFASTEDPLVLADRLRAARGDLPVDVVVQPAATRRK
KLFLADMDSTMIGQECIDELAGFVGLKDHVAAITERAMRGEIEFEPALRERVALLKGLPLDVIGQVLDTRITLTPGGRAV
VQTMRANGAYTCLVSGGFTQFTHVVAERLGFAEHRANELLSEDGKLTGTVAEPILGRDAKLATLLELREADDLDAIDTLV
VGDGANDLGMIQAAGLGIAYHAKPAVAAAAHGRIDFGDLTALLYAQGYRRDEFVAD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=179, Percent_Identity=32.9608938547486, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=43.6893203883495, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI115534454, Length=174, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534456, Length=174, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=233, Percent_Identity=38.1974248927039, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24661601, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31749; Mature: 31617

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVATLICNPNNPALDSTVIEGARAVLPQPNEAVWLHDEIAADIFFASTEDPLVLADRL
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHEEEEEECCCCCCHHHHHH
RAARGDLPVDVVVQPAATRRKKLFLADMDSTMIGQECIDELAGFVGLKDHVAAITERAMR
HHHCCCCCEEEEECCCHHHHHEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GEIEFEPALRERVALLKGLPLDVIGQVLDTRITLTPGGRAVVQTMRANGAYTCLVSGGFT
CCCEECHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCCHHHHHHHHCCCCEEEEEECCHH
QFTHVVAERLGFAEHRANELLSEDGKLTGTVAEPILGRDAKLATLLELREADDLDAIDTL
HHHHHHHHHHCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCCCCCCHHHEE
VVGDGANDLGMIQAAGLGIAYHAKPAVAAAAHGRIDFGDLTALLYAQGYRRDEFVAD
EECCCCCCCCCEEECCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLVATLICNPNNPALDSTVIEGARAVLPQPNEAVWLHDEIAADIFFASTEDPLVLADRL
CEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHEEEEEECCCCCCHHHHHH
RAARGDLPVDVVVQPAATRRKKLFLADMDSTMIGQECIDELAGFVGLKDHVAAITERAMR
HHHCCCCCEEEEECCCHHHHHEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GEIEFEPALRERVALLKGLPLDVIGQVLDTRITLTPGGRAVVQTMRANGAYTCLVSGGFT
CCCEECHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCCHHHHHHHHCCCCEEEEEECCHH
QFTHVVAERLGFAEHRANELLSEDGKLTGTVAEPILGRDAKLATLLELREADDLDAIDTL
HHHHHHHHHHCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHCCCCCCHHHEE
VVGDGANDLGMIQAAGLGIAYHAKPAVAAAAHGRIDFGDLTALLYAQGYRRDEFVAD
EECCCCCCCCCEEECCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]