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The map label for this gene is thcR [H]

Identifier: 192290592

GI number: 192290592

Start: 2384437

End: 2385444

Strand: Reverse

Name: thcR [H]

Synonym: Rpal_2201

Alternate gene names: 192290592

Gene position: 2385444-2384437 (Counterclockwise)

Preceding gene: 192290595

Following gene: 192290591

Centisome position: 41.53

GC content: 61.9

Gene sequence:

>1008_bases
ATGCATGCCCGTGGCGCCGACGTTCATGCCAACCCGCTCAGTTCTTTTCGCCATGTGAAGACGGGAAGCATCGAACTTCT
GGAGCACGAGCTTGGTCGTTTTTATCCGGGCATCCGGTTTGAATTGGACAATCCCGACGGCGCACTCAATGCGGAGGCCA
GTCGATGTGAATTGAGCGATATTGCTCTGACCTATGGACGGCACGGCACCGGCATCACCATCGACGTCCCGTACAACAAC
ACGCATTCGCTGGTGTTCGCCTACGCCGGCAGCGCTGAAGCCCGCACGGGCCGACTCCGCTCAGACATCGCGGGGCACCG
CGCCTTCGTTGCCTCCGCAACTCGGCCGGTGACGCTCAAATACGCGCCGGATTTCGAGCAGCTCATTCTGAACGTTTCAC
AGCGGTCGGTCACAACCAACCTCGAGGCGCTGATCGGCGCCCCGCTCAGTCAACCGATCATCTTCAAGCCCACTTCGAAT
CTTCGGCGCACGTCGGCGCGCAGGCTGTGGGAGCAGTTGATGTCTCTCGTCGAGCGGCTGGGCCGACACGACGGTGGGTA
TCATCAGCAAATCACGACCGAGCTCGAGCAGGCGATCATCCTGTCTTTCCTGACCGCCAATGAGAGCAACTACACTCCAT
TGCTGATGAGCGAGGCCGCCGCTGCCGGCAGGCGGCCGGTCCATAAGGTGGCGGACTATCTCGAGGCATACTGGGACCAG
CCGCTGACAGTGGAGATGCTGGCGCGGGTGAGCGGAGTGAGCGTACGGACTCTCTTCCACAGTTTCCGCGGGCAGTTCGG
CTATTCCCCGATGGAGTTCGTCAGGCGCATTCGTCTTGAACGGGCCCGCCAGATGCTGGCCGGCGCCGATCCGGCGCTTT
CGGTGACATCGGTCGCGCTCTCCTGCGGCTTTGGCAATCTTGGTCACTTCGCGGGCTATTATAAGAAGGCGTTCGGCGAA
GCGCCGTCGGCCACGCTGTCGCGCGCCAGGAGCCCTGCATCGTCCTGA

Upstream 100 bases:

>100_bases
CCTCACCGTCTGCAGGAGTCGCGGATTGCCGGTCGGTCGCAATCGCGATATGCAGGACTGATACACTGATTGCTTTTGCA
ACGACGATACAGGTGTTCGA

Downstream 100 bases:

>100_bases
CTGCGAAGCCGGCTGGTCGCCCCGTCATCGGCACCGACCATTCTGGTTGCGGCGCCTCACGAGACGTGAGTCATCCCAGC
ATCTGGAACGGCTGCGACGG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MHARGADVHANPLSSFRHVKTGSIELLEHELGRFYPGIRFELDNPDGALNAEASRCELSDIALTYGRHGTGITIDVPYNN
THSLVFAYAGSAEARTGRLRSDIAGHRAFVASATRPVTLKYAPDFEQLILNVSQRSVTTNLEALIGAPLSQPIIFKPTSN
LRRTSARRLWEQLMSLVERLGRHDGGYHQQITTELEQAIILSFLTANESNYTPLLMSEAAAAGRRPVHKVADYLEAYWDQ
PLTVEMLARVSGVSVRTLFHSFRGQFGYSPMEFVRRIRLERARQMLAGADPALSVTSVALSCGFGNLGHFAGYYKKAFGE
APSATLSRARSPASS

Sequences:

>Translated_335_residues
MHARGADVHANPLSSFRHVKTGSIELLEHELGRFYPGIRFELDNPDGALNAEASRCELSDIALTYGRHGTGITIDVPYNN
THSLVFAYAGSAEARTGRLRSDIAGHRAFVASATRPVTLKYAPDFEQLILNVSQRSVTTNLEALIGAPLSQPIIFKPTSN
LRRTSARRLWEQLMSLVERLGRHDGGYHQQITTELEQAIILSFLTANESNYTPLLMSEAAAAGRRPVHKVADYLEAYWDQ
PLTVEMLARVSGVSVRTLFHSFRGQFGYSPMEFVRRIRLERARQMLAGADPALSVTSVALSCGFGNLGHFAGYYKKAFGE
APSATLSRARSPASS
>Mature_335_residues
MHARGADVHANPLSSFRHVKTGSIELLEHELGRFYPGIRFELDNPDGALNAEASRCELSDIALTYGRHGTGITIDVPYNN
THSLVFAYAGSAEARTGRLRSDIAGHRAFVASATRPVTLKYAPDFEQLILNVSQRSVTTNLEALIGAPLSQPIIFKPTSN
LRRTSARRLWEQLMSLVERLGRHDGGYHQQITTELEQAIILSFLTANESNYTPLLMSEAAAAGRRPVHKVADYLEAYWDQ
PLTVEMLARVSGVSVRTLFHSFRGQFGYSPMEFVRRIRLERARQMLAGADPALSVTSVALSCGFGNLGHFAGYYKKAFGE
APSATLSRARSPASS

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36864; Mature: 36864

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHARGADVHANPLSSFRHVKTGSIELLEHELGRFYPGIRFELDNPDGALNAEASRCELSD
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHH
IALTYGRHGTGITIDVPYNNTHSLVFAYAGSAEARTGRLRSDIAGHRAFVASATRPVTLK
HHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHEECCCCCEEEE
YAPDFEQLILNVSQRSVTTNLEALIGAPLSQPIIFKPTSNLRRTSARRLWEQLMSLVERL
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
GRHDGGYHQQITTELEQAIILSFLTANESNYTPLLMSEAAAAGRRPVHKVADYLEAYWDQ
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCC
PLTVEMLARVSGVSVRTLFHSFRGQFGYSPMEFVRRIRLERARQMLAGADPALSVTSVAL
CCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SCGFGNLGHFAGYYKKAFGEAPSATLSRARSPASS
HCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MHARGADVHANPLSSFRHVKTGSIELLEHELGRFYPGIRFELDNPDGALNAEASRCELSD
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHH
IALTYGRHGTGITIDVPYNNTHSLVFAYAGSAEARTGRLRSDIAGHRAFVASATRPVTLK
HHHCCCCCCCCEEEECCCCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHEECCCCCEEEE
YAPDFEQLILNVSQRSVTTNLEALIGAPLSQPIIFKPTSNLRRTSARRLWEQLMSLVERL
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
GRHDGGYHQQITTELEQAIILSFLTANESNYTPLLMSEAAAAGRRPVHKVADYLEAYWDQ
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCC
PLTVEMLARVSGVSVRTLFHSFRGQFGYSPMEFVRRIRLERARQMLAGADPALSVTSVAL
CCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SCGFGNLGHFAGYYKKAFGEAPSATLSRARSPASS
HCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]