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The map label for this gene is aaeA [H]

Identifier: 192290553

GI number: 192290553

Start: 2340006

End: 2340881

Strand: Reverse

Name: aaeA [H]

Synonym: Rpal_2162

Alternate gene names: 192290553

Gene position: 2340881-2340006 (Counterclockwise)

Preceding gene: 192290554

Following gene: 192290548

Centisome position: 40.75

GC content: 68.49

Gene sequence:

>876_bases
ATGGGAAAGACTCCGCTTCTGCTCGTCCGCCTCAGCGTCACCACGCTCGGCGTCCTGGTCGCCGCACTGATCGGCTGGCG
GCTGTGGGTCCACTACGAGATCGAGCCGTGGACGCGCGACGGCCGTGTGCGCGCCGACATCGTCGCGGTGGCGCCGGACG
TCTCCGGCCTCGTCTCCGAGGTGCTGGTCGTCGACAACCAGGTGGTGAAGAAGGGCGACATCCTATTCCGGATCGATCGC
GAGCGCTTCACCTTGGCGCTGCGCCAGGCCGACGCCGCGGTCGAAGGCCGCGTCGCCGCGCTCGACGCCGCCAACAAGGA
TCTGGCCCGCTATCGCAATCTCAGCAGCGACGCCGTCACCGAGCAGAAGCGCGAGCAGATCACCGCCACCCAGGCCGAAG
CTGAAGCTGCGCTGCATCAGGCGATCGCCGATCGGGATATCGCCAAGCTCAATCTCGACCGATCGGAAGTCCGCGCCCAG
GTCGGCGGCCTGATCACCAATTTCGATCTGCGCCCCGGTGCCTATGTCAACGCCGGCAGCGGCGTCGCCGCGCTGATCGA
TCAGGCGACGCTGCATGTCGATGGTTACTTCGAGGAGACCAAGCTGCCCTCCATCCGTGTCGGCGATCGGGCCGAGGTGC
GGCTGATGGGCGAGCGCAACCCGCTCTCCGGTCACGTCCAGAGCATCGCCGGTGGCATCGAGGACCGCGACCGCAGCGCC
GGCGCCAAGCTGCTGCCGAACGTCAACCCGACCTTCAACTGGGTGCGGCTGGCACAGCGAATTCCGGTGCGGATCGCGCT
CGACCACGTGCCGCCCGAGGTGCGCCTCGTGGTCGGCCGCACCGCCACCGTGGTGATCGAGCGCCGCGGCGGCTGA

Upstream 100 bases:

>100_bases
TCGTCTGGCATCACACCTTGTTCAATCTCACCATCTTCGTCGTCATCGTGTTCGTCGCTCTCGGTCTCGTTTCGGGGTGG
CCGCAATGAAAGGGCCAGCC

Downstream 100 bases:

>100_bases
CCGCCGAACGAACTACCCTCCGTCATTCCGGATTGCGCGGTACGCGCAAGTCCGGAATCCATAGCCCCTGGACTCGCGGT
GAAGCACTGAGGCGGCAAGC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MGKTPLLLVRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSEVLVVDNQVVKKGDILFRIDR
ERFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVTEQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQ
VGGLITNFDLRPGAYVNAGSGVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSA
GAKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG

Sequences:

>Translated_291_residues
MGKTPLLLVRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSEVLVVDNQVVKKGDILFRIDR
ERFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVTEQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQ
VGGLITNFDLRPGAYVNAGSGVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSA
GAKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG
>Mature_290_residues
GKTPLLLVRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSEVLVVDNQVVKKGDILFRIDRE
RFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVTEQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQV
GGLITNFDLRPGAYVNAGSGVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSAG
AKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=278, Percent_Identity=38.8489208633094, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789637, Length=280, Percent_Identity=40, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1790519, Length=319, Percent_Identity=29.7805642633229, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789041, Length=304, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788711, Length=328, Percent_Identity=25, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 31774; Mature: 31643

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTPLLLVRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSE
CCCCCEEEEEEHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHH
VLVVDNQVVKKGDILFRIDRERFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVT
HHHHCCHHEECCCEEEEECHHHHEEHHHHHCHHHCCEEEEECCCCHHHHHHHCCCHHHHH
EQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQVGGLITNFDLRPGAYVNAGS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHCCEEEEECCCCCCEEECCC
GVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSA
CHHHHHHCEEEEECCEECCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCC
GAKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG
CCEECCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEEEECCC
>Mature Secondary Structure 
GKTPLLLVRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSE
CCCCEEEEEEHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHH
VLVVDNQVVKKGDILFRIDRERFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVT
HHHHCCHHEECCCEEEEECHHHHEEHHHHHCHHHCCEEEEECCCCHHHHHHHCCCHHHHH
EQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQVGGLITNFDLRPGAYVNAGS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHCCEEEEECCCCCCEEECCC
GVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSA
CHHHHHHCEEEEECCEECCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCC
GAKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG
CCEECCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA