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The map label for this gene is oxlT [H]

Identifier: 192290545

GI number: 192290545

Start: 2332511

End: 2333803

Strand: Reverse

Name: oxlT [H]

Synonym: Rpal_2154

Alternate gene names: 192290545

Gene position: 2333803-2332511 (Counterclockwise)

Preceding gene: 192290546

Following gene: 192290544

Centisome position: 40.63

GC content: 64.04

Gene sequence:

>1293_bases
ATGACGGACACGGTGCACGGGGTGGCCGCCGCGCAGACGCGGCGCGTGAGTGAGAGCTATCGCTGGACGCAACTCGCCAT
CGGCGTCGGCGCGATGGTGATGATCGCCAACTACCAATACGGCTGGACGTTCTTCGTCCCCGACATTCAGAAAACCTTCG
GCTGGGACCGCGCCTCGATCCAATGGGCATTCACCCTCTTCGTATTGTTCGAGACCTGGCTGGTGCCGATCGAGGGCTGG
TTCGTGGACAAATACGGCCCGCGTCTGGTGGTGCTGATCGGCGGCATCCTGTGTGCGCTCGGCTGGGCGATCAACGCGCA
GGCGACGACGCTGTCGGGTTTCTACCTCGGCATGATCGTCGCGGGCATCGGCGCTGGTGCGGTCTATGGCACCTGCGTGG
GCAACGCGCTGAAATGGTTTCCGGACAAGCGCGGATTAGCGGCCGGATTGACGGCGGCGGGCTTCGGGGCCGGCTCGGCG
CTCACGGTGGCGCCGATCCAGGCGATGATCCGCGACTCCGGCTTTCAGACCACCTTCATGTATTTCGGTCTCGGCCAGGG
CATCGTGATCGTGTTTCTGTCGCTGCTGCTGCTCGCGCCGAAGCCGGGACAGGTGCCGTCCCCGACCCGCAACGCCAACG
TCTTCCAGACGCGTCGCGACTACCGTCCGACCGAAGTGCTGCGCCAGCCGGTGTTCTGGCTGATGTACTTCATGTTCGTG
ATCGTCGGTGCCGGCGGGTTGATGGTCACCGCCAATCTGAAGCCGATCGCCGCCGACTGGAAGATCGCCGACACGCCCGT
CACGCTGATGGCGATGACCATGACGGCAGTGACCTTCGCAGCCACCTTCGATCGCATCCTCAACGGCCTGACGCGGCCGT
TCTTCGGCTGGATCTCGGACAAGATCGGCCGCGAGAATACGATGTTCATCGCGTTCGGGCTCGAAGGCATCGGCATCTAC
GCGCTGTATGCGCTGGGTCAGGATCCGGTGTGGTTCGTGCTGCTGTCGGGGCTGGTGTTCTTCGCCTGGGGCGAGATCTA
CTCGCTGTTTCCCTCAACCTGCACCGACACCTTCGGGTCGAAGTTCGCCGCCACCAATGCGGGCCTGCTGTACACCGCGA
AGGGCACCGCGGCGCTGCTGGTGCCATTCGCCAATTCGCTGCAGCAATCCAGCGGCAGTTGGGATCTGGTGTTCCTGATC
GCTGCCGCCGCCAACATCCTGGCGTCGCTGTTGGCGCTGCTGGTGCTCAAGCCATGGCGGCGCAGCGTCGTCGCCAAAAG
CGAAATGGTCTGA

Upstream 100 bases:

>100_bases
ACAAGTCACGTCGTTATTTCCCTCCTTGCGCCTGGTGATTAGCACGATCACAATGGCGACGGTACGGCTCCCGACAGAGG
CGCCGGCTCACGGAGGAAAC

Downstream 100 bases:

>100_bases
TCGACGCGGCGGGAGCGCACGCGTCGCAGGCAAATCTGGTCTCACCGCGGCGTGGCCGAATGGCCACGCCTGTCTTGTCG
TCTGTCTGATGGGAAATCGC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTDTVHGVAAAQTRRVSESYRWTQLAIGVGAMVMIANYQYGWTFFVPDIQKTFGWDRASIQWAFTLFVLFETWLVPIEGW
FVDKYGPRLVVLIGGILCALGWAINAQATTLSGFYLGMIVAGIGAGAVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSA
LTVAPIQAMIRDSGFQTTFMYFGLGQGIVIVFLSLLLLAPKPGQVPSPTRNANVFQTRRDYRPTEVLRQPVFWLMYFMFV
IVGAGGLMVTANLKPIAADWKIADTPVTLMAMTMTAVTFAATFDRILNGLTRPFFGWISDKIGRENTMFIAFGLEGIGIY
ALYALGQDPVWFVLLSGLVFFAWGEIYSLFPSTCTDTFGSKFAATNAGLLYTAKGTAALLVPFANSLQQSSGSWDLVFLI
AAAANILASLLALLVLKPWRRSVVAKSEMV

Sequences:

>Translated_430_residues
MTDTVHGVAAAQTRRVSESYRWTQLAIGVGAMVMIANYQYGWTFFVPDIQKTFGWDRASIQWAFTLFVLFETWLVPIEGW
FVDKYGPRLVVLIGGILCALGWAINAQATTLSGFYLGMIVAGIGAGAVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSA
LTVAPIQAMIRDSGFQTTFMYFGLGQGIVIVFLSLLLLAPKPGQVPSPTRNANVFQTRRDYRPTEVLRQPVFWLMYFMFV
IVGAGGLMVTANLKPIAADWKIADTPVTLMAMTMTAVTFAATFDRILNGLTRPFFGWISDKIGRENTMFIAFGLEGIGIY
ALYALGQDPVWFVLLSGLVFFAWGEIYSLFPSTCTDTFGSKFAATNAGLLYTAKGTAALLVPFANSLQQSSGSWDLVFLI
AAAANILASLLALLVLKPWRRSVVAKSEMV
>Mature_429_residues
TDTVHGVAAAQTRRVSESYRWTQLAIGVGAMVMIANYQYGWTFFVPDIQKTFGWDRASIQWAFTLFVLFETWLVPIEGWF
VDKYGPRLVVLIGGILCALGWAINAQATTLSGFYLGMIVAGIGAGAVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSAL
TVAPIQAMIRDSGFQTTFMYFGLGQGIVIVFLSLLLLAPKPGQVPSPTRNANVFQTRRDYRPTEVLRQPVFWLMYFMFVI
VGAGGLMVTANLKPIAADWKIADTPVTLMAMTMTAVTFAATFDRILNGLTRPFFGWISDKIGRENTMFIAFGLEGIGIYA
LYALGQDPVWFVLLSGLVFFAWGEIYSLFPSTCTDTFGSKFAATNAGLLYTAKGTAALLVPFANSLQQSSGSWDLVFLIA
AAANILASLLALLVLKPWRRSVVAKSEMV

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI24431958, Length=413, Percent_Identity=23.728813559322, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789969, Length=342, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46717; Mature: 46586

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVHGVAAAQTRRVSESYRWTQLAIGVGAMVMIANYQYGWTFFVPDIQKTFGWDRASI
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEECCCCEEEEECCHHHHCCCCCCHH
QWAFTLFVLFETWLVPIEGWFVDKYGPRLVVLIGGILCALGWAINAQATTLSGFYLGMIV
HHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
AGIGAGAVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSALTVAPIQAMIRDSGFQTTFM
HHHCCCHHHHHHHHHHHHHCCCCCCCHHCCHHCCCCCCCEEHHHHHHHHHHCCCCCEEEE
YFGLGQGIVIVFLSLLLLAPKPGQVPSPTRNANVFQTRRDYRPTEVLRQPVFWLMYFMFV
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
IVGAGGLMVTANLKPIAADWKIADTPVTLMAMTMTAVTFAATFDRILNGLTRPFFGWISD
HHCCCCEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGRENTMFIAFGLEGIGIYALYALGQDPVWFVLLSGLVFFAWGEIYSLFPSTCTDTFGS
HCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
KFAATNAGLLYTAKGTAALLVPFANSLQQSSGSWDLVFLIAAAANILASLLALLVLKPWR
CCEECCCCEEEEECCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
RSVVAKSEMV
HHHHHHHCCC
>Mature Secondary Structure 
TDTVHGVAAAQTRRVSESYRWTQLAIGVGAMVMIANYQYGWTFFVPDIQKTFGWDRASI
CCCCHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEECCCCEEEEECCHHHHCCCCCCHH
QWAFTLFVLFETWLVPIEGWFVDKYGPRLVVLIGGILCALGWAINAQATTLSGFYLGMIV
HHHHHHHHHHHHHHHCCCCEEECCCCCEEHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
AGIGAGAVYGTCVGNALKWFPDKRGLAAGLTAAGFGAGSALTVAPIQAMIRDSGFQTTFM
HHHCCCHHHHHHHHHHHHHCCCCCCCHHCCHHCCCCCCCEEHHHHHHHHHHCCCCCEEEE
YFGLGQGIVIVFLSLLLLAPKPGQVPSPTRNANVFQTRRDYRPTEVLRQPVFWLMYFMFV
EEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
IVGAGGLMVTANLKPIAADWKIADTPVTLMAMTMTAVTFAATFDRILNGLTRPFFGWISD
HHCCCCEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIGRENTMFIAFGLEGIGIYALYALGQDPVWFVLLSGLVFFAWGEIYSLFPSTCTDTFGS
HCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
KFAATNAGLLYTAKGTAALLVPFANSLQQSSGSWDLVFLIAAAANILASLLALLVLKPWR
CCEECCCCEEEEECCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
RSVVAKSEMV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]