Click here to switch to the map view.

The map label for this gene is sgbE [C]

Identifier: 192290448

GI number: 192290448

Start: 2228395

End: 2229177

Strand: Reverse

Name: sgbE [C]

Synonym: Rpal_2055

Alternate gene names: 192290448

Gene position: 2229177-2228395 (Counterclockwise)

Preceding gene: 192290451

Following gene: 192290447

Centisome position: 38.81

GC content: 65.01

Gene sequence:

>783_bases
ATGTCCCCAGCCGAAGCCGCACGCCTGAGAGAAGTCCCCTCCGACATGACCGAGGCCGAATGGGAGCAGCGGGTCAATCT
CGCTGCCTGCTATCGCCTGGTCGCGCTGTACGGCTGGGACGATCTGGTCGACACCCACATCTCCGCCCGGGTGCCCGGCC
CCGAGCATCACTTCCTGATCAACCCCTACGGGCTGATGTTCGACGAGATCACCGCCTCGAGCCTGGTCAAGGTCGACCTC
GACGGCAACCAGCTCACCGAGAGCCCGTACAAGATCAACCCGGCCGGCTTCACCATCCATTCGGCGATCCATGAGGTCCG
TGAGGACGCCGGCTGCGTCATCCATCTGCACACGCCGGACGGGACCGCGGTGGCGAGCTGCATGGACGGCCTGCTGCCGA
TCAACCAGACCGCGCATTTCGTCACCGGCGACCTCGCCTATCACGACTATGAAGGCGTCGCGCTCGATCATGACGAGCGG
CCGCGGCTGCAGCGCGATCTCGGCGACAAGAACCACATGCTGCTCCGCAATCACGGGACGCTGACGGTCGGCCGCACCGT
CGCGTCGGCTTTCGAACGGATGTATCATCTCGAGCGCGCCTGCACGATGCAGGTCCGCACCAAGATGCTCGGCCCGACGG
CGTACCCGCTCGAGCAGATGGTGATCGACAAGAACCACGACCTGATCGCCAATCGCGACGCGATGGAGCTGCGCTCCACC
AAGCTGGTGTGGCCGCCGCTGCTGCGCAAACTCGACCGCATCGATCCGAGCTATCGGAGCTGA

Upstream 100 bases:

>100_bases
CTGCTGCGCTCAGGTCGCCGCTTGCTGCAAGGCATTCGCAGCCCTAGGCTTCCGCCAAGTCAACGCGCCGGGCAACGGCG
CTCACACGAAGAGGAAACGC

Downstream 100 bases:

>100_bases
AGCCGTCATTGCGAGCGCAGCGAAGCAATGCAGACACTCGCACACCAAGTGGGTTGCTTCGTCGGCCTCGCTCATCGCAA
TGACGCTGTGATTGGCGGAG

Product: aldolase II superfamily protein

Products: xylulose-5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSPAEAARLREVPSDMTEAEWEQRVNLAACYRLVALYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDL
DGNQLTESPYKINPAGFTIHSAIHEVREDAGCVIHLHTPDGTAVASCMDGLLPINQTAHFVTGDLAYHDYEGVALDHDER
PRLQRDLGDKNHMLLRNHGTLTVGRTVASAFERMYHLERACTMQVRTKMLGPTAYPLEQMVIDKNHDLIANRDAMELRST
KLVWPPLLRKLDRIDPSYRS

Sequences:

>Translated_260_residues
MSPAEAARLREVPSDMTEAEWEQRVNLAACYRLVALYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDL
DGNQLTESPYKINPAGFTIHSAIHEVREDAGCVIHLHTPDGTAVASCMDGLLPINQTAHFVTGDLAYHDYEGVALDHDER
PRLQRDLGDKNHMLLRNHGTLTVGRTVASAFERMYHLERACTMQVRTKMLGPTAYPLEQMVIDKNHDLIANRDAMELRST
KLVWPPLLRKLDRIDPSYRS
>Mature_259_residues
SPAEAARLREVPSDMTEAEWEQRVNLAACYRLVALYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDLD
GNQLTESPYKINPAGFTIHSAIHEVREDAGCVIHLHTPDGTAVASCMDGLLPINQTAHFVTGDLAYHDYEGVALDHDERP
RLQRDLGDKNHMLLRNHGTLTVGRTVASAFERMYHLERACTMQVRTKMLGPTAYPLEQMVIDKNHDLIANRDAMELRSTK
LVWPPLLRKLDRIDPSYRS

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=187, Percent_Identity=47.5935828877005, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI29826325, Length=187, Percent_Identity=47.5935828877005, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI29826319, Length=187, Percent_Identity=47.5935828877005, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI29826321, Length=187, Percent_Identity=47.5935828877005, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI9257190, Length=194, Percent_Identity=41.7525773195876, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI89276787, Length=194, Percent_Identity=41.7525773195876, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI297307158, Length=194, Percent_Identity=41.7525773195876, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI9257192, Length=194, Percent_Identity=41.7525773195876, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI297307160, Length=194, Percent_Identity=41.7525773195876, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI9943848, Length=196, Percent_Identity=41.8367346938776, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI9951927, Length=196, Percent_Identity=41.8367346938776, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI62912453, Length=196, Percent_Identity=41.8367346938776, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI115533216, Length=249, Percent_Identity=39.3574297188755, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI115533218, Length=249, Percent_Identity=39.3574297188755, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71989560, Length=250, Percent_Identity=33.6, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71989555, Length=245, Percent_Identity=33.8775510204082, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71989550, Length=245, Percent_Identity=33.8775510204082, Blast_Score=133, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71989544, Length=245, Percent_Identity=33.8775510204082, Blast_Score=133, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71989541, Length=245, Percent_Identity=33.8775510204082, Blast_Score=133, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281363763, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363757, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17136738, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363755, Length=187, Percent_Identity=40.1069518716578, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363751, Length=187, Percent_Identity=40.1069518716578, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24655690, Length=187, Percent_Identity=40.1069518716578, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24655685, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363761, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363759, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363753, Length=192, Percent_Identity=39.5833333333333, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: 5.1.-.- [C]

Molecular weight: Translated: 29334; Mature: 29203

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAEAARLREVPSDMTEAEWEQRVNLAACYRLVALYGWDDLVDTHISARVPGPEHHFLI
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEEE
NPYGLMFDEITASSLVKVDLDGNQLTESPYKINPAGFTIHSAIHEVREDAGCVIHLHTPD
CCHHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEECCC
GTAVASCMDGLLPINQTAHFVTGDLAYHDYEGVALDHDERPRLQRDLGDKNHMLLRNHGT
CHHHHHHHHCCCCCCCCCCEEECCEEEECCCCEEECCCCCCHHHHHCCCCCCEEEECCCC
LTVGRTVASAFERMYHLERACTMQVRTKMLGPTAYPLEQMVIDKNHDLIANRDAMELRST
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCHHHHHCC
KLVWPPLLRKLDRIDPSYRS
CCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPAEAARLREVPSDMTEAEWEQRVNLAACYRLVALYGWDDLVDTHISARVPGPEHHFLI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEEE
NPYGLMFDEITASSLVKVDLDGNQLTESPYKINPAGFTIHSAIHEVREDAGCVIHLHTPD
CCHHHHHHHHCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEECCC
GTAVASCMDGLLPINQTAHFVTGDLAYHDYEGVALDHDERPRLQRDLGDKNHMLLRNHGT
CHHHHHHHHCCCCCCCCCCEEECCEEEECCCCEEECCCCCCHHHHHCCCCCCEEEECCCC
LTVGRTVASAFERMYHLERACTMQVRTKMLGPTAYPLEQMVIDKNHDLIANRDAMELRST
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCHHHHHCC
KLVWPPLLRKLDRIDPSYRS
CCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ribulose-5-phosphate [C]

Specific reaction: L-ribulose-5-phosphate = xylulose-5-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]