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The map label for this gene is argK [C]

Identifier: 192290426

GI number: 192290426

Start: 2205842

End: 2206831

Strand: Reverse

Name: argK [C]

Synonym: Rpal_2033

Alternate gene names: 192290426

Gene position: 2206831-2205842 (Counterclockwise)

Preceding gene: 192290427

Following gene: 192290425

Centisome position: 38.42

GC content: 69.19

Gene sequence:

>990_bases
ATGAATTCAGCCCGACGCACCGGCGACATTGCCCATTTCGCCAGCGAGGTCCGCAGCGGCCATCGCGCCGCGCTGGCGCG
CGCCATCACCCTGATCGAAAGCCGCCGAGCCGACCACCAGGCGTCCGCGCGCGCGCTGGTGCAGGACCTGCTGCCCGAAA
CCGGCCGCGCGATCCGCGTCGGCATCACCGGCTCACCCGGCGTCGGCAAGTCGACCACCATCGACGCGCTCGGCATGTAT
CTGATCGAGCAGGGCCACAAGGTCGCGGTGCTGGCGGTCGATCCGTCATCGGCGCGCACCGGCGGGTCAATTCTCGGCGA
CAAGACCCGGATGGCGCGGCTATCCGCCGAGCCGGACGCCTTCATCCGTCCCTCGCCCTCCTCCGGCACGCTTGGCGGCG
TCGCGGCGAAGACCCGCGAGGCGATGCTGCTGTGCGAGGCCGCCGGCTTCGACGTCGTGCTGGTCGAGACCGTCGGCATC
GGCCAATCCGAAACCGCGGTCTGCGATATGACCGATTTCTTTCTGGCGCTGATGCTGCCGGGCGCCGGCGACGAGTTGCA
GGGCATCAAGAAGGGCCTGGTCGAGCTCGCCGACATGATCGCCATCAACAAGGCGGACGGCGACAACATCAAGCGCGCCA
ATCTCGCCGCCGGCGAGTATCGCGCGGCGCTGCATATCCTCACCCCGCGTTCGCCGAACTGGCAGCCGCCGGTGAAGACC
TATTCGGCAATGACCGGCACCGGCATCGCCGAGCTGTGGCAGGCGATCCTGGACCATCGCGCCGCCACCACGCCGTCGGG
CGAGTTCGACGCCCGCCGCCGCGAGCAGCAGGTGAAGTGGATGTGGACGCTGCTCGAGGATCGTTGGAAGGCGAAGCTGC
GCAGCGACCCGGCGATCCGCGCCAAGGTGAAATCGACCGAGGCCGCCGTCGCCGAAGGCTCGATCACGCCCACGCTCGGC
GCCGATCGGGTCGCGGAGCTGATCGGGTGA

Upstream 100 bases:

>100_bases
GACCCGCCGCCTGAAGCGTCATCAACAGGGAGATCCGCGCGCGCTCATTCCGCGCCGGACTCCCCTCGCTCCTGGCGCCC
AATCGTTGTAAACGGGCGCC

Downstream 100 bases:

>100_bases
GTGGCCTGCGCATCCTGATCACCGGCTTCGGGCCGTTTCCCGGAGCGCCTTACAATCCGACTCCGCAATTGGTCGATCGC
CTCGTCAAGCTGCGGAGGCC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNSARRTGDIAHFASEVRSGHRAALARAITLIESRRADHQASARALVQDLLPETGRAIRVGITGSPGVGKSTTIDALGMY
LIEQGHKVAVLAVDPSSARTGGSILGDKTRMARLSAEPDAFIRPSPSSGTLGGVAAKTREAMLLCEAAGFDVVLVETVGI
GQSETAVCDMTDFFLALMLPGAGDELQGIKKGLVELADMIAINKADGDNIKRANLAAGEYRAALHILTPRSPNWQPPVKT
YSAMTGTGIAELWQAILDHRAATTPSGEFDARRREQQVKWMWTLLEDRWKAKLRSDPAIRAKVKSTEAAVAEGSITPTLG
ADRVAELIG

Sequences:

>Translated_329_residues
MNSARRTGDIAHFASEVRSGHRAALARAITLIESRRADHQASARALVQDLLPETGRAIRVGITGSPGVGKSTTIDALGMY
LIEQGHKVAVLAVDPSSARTGGSILGDKTRMARLSAEPDAFIRPSPSSGTLGGVAAKTREAMLLCEAAGFDVVLVETVGI
GQSETAVCDMTDFFLALMLPGAGDELQGIKKGLVELADMIAINKADGDNIKRANLAAGEYRAALHILTPRSPNWQPPVKT
YSAMTGTGIAELWQAILDHRAATTPSGEFDARRREQQVKWMWTLLEDRWKAKLRSDPAIRAKVKSTEAAVAEGSITPTLG
ADRVAELIG
>Mature_329_residues
MNSARRTGDIAHFASEVRSGHRAALARAITLIESRRADHQASARALVQDLLPETGRAIRVGITGSPGVGKSTTIDALGMY
LIEQGHKVAVLAVDPSSARTGGSILGDKTRMARLSAEPDAFIRPSPSSGTLGGVAAKTREAMLLCEAAGFDVVLVETVGI
GQSETAVCDMTDFFLALMLPGAGDELQGIKKGLVELADMIAINKADGDNIKRANLAAGEYRAALHILTPRSPNWQPPVKT
YSAMTGTGIAELWQAILDHRAATTPSGEFDARRREQQVKWMWTLLEDRWKAKLRSDPAIRAKVKSTEAAVAEGSITPTLG
ADRVAELIG

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=314, Percent_Identity=48.4076433121019, Blast_Score=301, Evalue=6e-82,
Organism=Escherichia coli, GI1789285, Length=312, Percent_Identity=50.3205128205128, Blast_Score=309, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI71994271, Length=325, Percent_Identity=43.6923076923077, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71994275, Length=266, Percent_Identity=45.8646616541353, Blast_Score=248, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35000; Mature: 35000

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSARRTGDIAHFASEVRSGHRAALARAITLIESRRADHQASARALVQDLLPETGRAIRV
CCCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEE
GITGSPGVGKSTTIDALGMYLIEQGHKVAVLAVDPSSARTGGSILGDKTRMARLSAEPDA
EECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
FIRPSPSSGTLGGVAAKTREAMLLCEAAGFDVVLVETVGIGQSETAVCDMTDFFLALMLP
CCCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHCC
GAGDELQGIKKGLVELADMIAINKADGDNIKRANLAAGEYRAALHILTPRSPNWQPPVKT
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHH
YSAMTGTGIAELWQAILDHRAATTPSGEFDARRREQQVKWMWTLLEDRWKAKLRSDPAIR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
AKVKSTEAAVAEGSITPTLGADRVAELIG
EEHHHHHHHHHCCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MNSARRTGDIAHFASEVRSGHRAALARAITLIESRRADHQASARALVQDLLPETGRAIRV
CCCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEE
GITGSPGVGKSTTIDALGMYLIEQGHKVAVLAVDPSSARTGGSILGDKTRMARLSAEPDA
EECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
FIRPSPSSGTLGGVAAKTREAMLLCEAAGFDVVLVETVGIGQSETAVCDMTDFFLALMLP
CCCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHCC
GAGDELQGIKKGLVELADMIAINKADGDNIKRANLAAGEYRAALHILTPRSPNWQPPVKT
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHH
YSAMTGTGIAELWQAILDHRAATTPSGEFDARRREQQVKWMWTLLEDRWKAKLRSDPAIR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
AKVKSTEAAVAEGSITPTLGADRVAELIG
EEHHHHHHHHHCCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]