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The map label for this gene is ttuD [H]

Identifier: 192290393

GI number: 192290393

Start: 2163440

End: 2164720

Strand: Reverse

Name: ttuD [H]

Synonym: Rpal_2000

Alternate gene names: 192290393

Gene position: 2164720-2163440 (Counterclockwise)

Preceding gene: 192290394

Following gene: 192290390

Centisome position: 37.69

GC content: 70.96

Gene sequence:

>1281_bases
ATGACCGATCGTCGCCCACTGCTTCGCGCCATCTTCGATGCGGCCGTCGCCGCCGCGCATCCCGACCGCATTCTCGCCGC
GCATCTGCCTCCGGCGCCGAGCGGGCGGATCATCTGCCTCGCGGCCGGCAAAGGCGCTGCCGCAATGGCAGCCGCCGCCG
AGCGGCACTATCTCGACACGTTGGGTCTGGAACCGTCGCGGCTGATCGGCCTCGCCACCACGCGCCACGGACACCGTGTG
CCGACGCGCGTCATCGAGGTGATCGAGGCCGGTCATCCGATGCCCGACGCCGCCGGGGTGCGCGGCGCCGAAACGAGCCT
CGCCCTCGCCGCTACCGCCACGCAGGACGACCTGTTGCTCGTGCTGCTGTCAGGCGGCGGCTCGGCCAATTGGATCGCGC
CGACGGAGGACGTGACGCTGGCGCAGAAACAGCAGGCGACCCGGGCGCTGCTGCGCTCCGGTGCACCGATCGGCGAAGTC
AACACGGTGCGCAAACATCTATCGCGGATCAAAGGTGGCCGCCTCGCCCGCGCCGGCGAGCACGCCGGGCAGATCGCGAC
CCTGGCGATCTCGGACGTGCCGCGCGACGAACCGTCCGCCATTGCGTCGGGCCCGACCGTGCCCGATCCGACCACGCTGG
CCGATGCCCGCGCGCTGGTGGCACGCTATGGTCTGGAGCTCGATCCGGCGGTCGCCGCCGCACTGAACGATGAGCGCAAC
GAAAGCGTCAAGGCCGGCGACGGCGCGTTTGCGCATGCGCGGTTCGAGATCATCGCGCGGCCGCGACAGTCGCTCGATGC
GGCGATCGAGGTTGCACGTACGGCCGGCTACGAAATCGCCGATCTCGGCGCCGATCTCGAAGGCGAGGCCCGCGAGGTCG
CCGCCGCGCACGCGCAGCTTGCGCGCGAGGCTCGCGCTCACGGGCGCAAGCTGGCGATCCTGTCCGGCGGCGAACTCACC
GTGACAGTGCGCGGCCAGGGCCGCGGCGGCCCCAACCAGGAATACGCGCTGGCGCTGGCGCAGCAGCTGTCGGACCTACC
CGACATCGCGGCGCTCGCGGCCGACACCGACGGCGCCGACGGCGGCGCCGGCAACGCCGACGACCCCGCCGGCGCACTGA
TCGACGCGGCAACCTTCACGCAGATCGCGGCGTTGCAGCTCGATCCCGCCGCGTATCTCGCCGACAACGACGCCACCGGC
TTCTTCGCCAAAACCGGCGACCTGCTGATCACCGGCCCGACACTGACCAACGTCAACGATATCCGTGTGATCTTGGTGTG
A

Upstream 100 bases:

>100_bases
AGAAGGCCGCACGGCACAAGAAGCGGGACGGCTCGTCGTCCTGCTCGGTCTCGGCGCGTCCGTCTTGCCGCCCCGCGGCG
CGCCTGCCACAACTGGCGGC

Downstream 100 bases:

>100_bases
GGCGCCCGCACCGTCGTCATCGCGAGAAGCGCAGCGACGGAGCATTCCTGAAGCCACAGTGCACAGGGCCCTGCATTGCG
GCGCTTCGCTCGTAACGACG

Product: Hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTDRRPLLRAIFDAAVAAAHPDRILAAHLPPAPSGRIICLAAGKGAAAMAAAAERHYLDTLGLEPSRLIGLATTRHGHRV
PTRVIEVIEAGHPMPDAAGVRGAETSLALAATATQDDLLLVLLSGGGSANWIAPTEDVTLAQKQQATRALLRSGAPIGEV
NTVRKHLSRIKGGRLARAGEHAGQIATLAISDVPRDEPSAIASGPTVPDPTTLADARALVARYGLELDPAVAAALNDERN
ESVKAGDGAFAHARFEIIARPRQSLDAAIEVARTAGYEIADLGADLEGEAREVAAAHAQLAREARAHGRKLAILSGGELT
VTVRGQGRGGPNQEYALALAQQLSDLPDIAALAADTDGADGGAGNADDPAGALIDAATFTQIAALQLDPAAYLADNDATG
FFAKTGDLLITGPTLTNVNDIRVILV

Sequences:

>Translated_426_residues
MTDRRPLLRAIFDAAVAAAHPDRILAAHLPPAPSGRIICLAAGKGAAAMAAAAERHYLDTLGLEPSRLIGLATTRHGHRV
PTRVIEVIEAGHPMPDAAGVRGAETSLALAATATQDDLLLVLLSGGGSANWIAPTEDVTLAQKQQATRALLRSGAPIGEV
NTVRKHLSRIKGGRLARAGEHAGQIATLAISDVPRDEPSAIASGPTVPDPTTLADARALVARYGLELDPAVAAALNDERN
ESVKAGDGAFAHARFEIIARPRQSLDAAIEVARTAGYEIADLGADLEGEAREVAAAHAQLAREARAHGRKLAILSGGELT
VTVRGQGRGGPNQEYALALAQQLSDLPDIAALAADTDGADGGAGNADDPAGALIDAATFTQIAALQLDPAAYLADNDATG
FFAKTGDLLITGPTLTNVNDIRVILV
>Mature_425_residues
TDRRPLLRAIFDAAVAAAHPDRILAAHLPPAPSGRIICLAAGKGAAAMAAAAERHYLDTLGLEPSRLIGLATTRHGHRVP
TRVIEVIEAGHPMPDAAGVRGAETSLALAATATQDDLLLVLLSGGGSANWIAPTEDVTLAQKQQATRALLRSGAPIGEVN
TVRKHLSRIKGGRLARAGEHAGQIATLAISDVPRDEPSAIASGPTVPDPTTLADARALVARYGLELDPAVAAALNDERNE
SVKAGDGAFAHARFEIIARPRQSLDAAIEVARTAGYEIADLGADLEGEAREVAAAHAQLAREARAHGRKLAILSGGELTV
TVRGQGRGGPNQEYALALAQQLSDLPDIAALAADTDGADGGAGNADDPAGALIDAATFTQIAALQLDPAAYLADNDATGF
FAKTGDLLITGPTLTNVNDIRVILV

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=490, Percent_Identity=34.0816326530612, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI193205461, Length=463, Percent_Identity=28.9416846652268, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19920578, Length=384, Percent_Identity=29.6875, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43796; Mature: 43665

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRRPLLRAIFDAAVAAAHPDRILAAHLPPAPSGRIICLAAGKGAAAMAAAAERHYLDT
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LGLEPSRLIGLATTRHGHRVPTRVIEVIEAGHPMPDAAGVRGAETSLALAATATQDDLLL
CCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
VLLSGGGSANWIAPTEDVTLAQKQQATRALLRSGAPIGEVNTVRKHLSRIKGGRLARAGE
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCC
HAGQIATLAISDVPRDEPSAIASGPTVPDPTTLADARALVARYGLELDPAVAAALNDERN
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
ESVKAGDGAFAHARFEIIARPRQSLDAAIEVARTAGYEIADLGADLEGEAREVAAAHAQL
CCEECCCCCEEHEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
AREARAHGRKLAILSGGELTVTVRGQGRGGPNQEYALALAQQLSDLPDIAALAADTDGAD
HHHHHHCCCEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC
GGAGNADDPAGALIDAATFTQIAALQLDPAAYLADNDATGFFAKTGDLLITGPTLTNVND
CCCCCCCCCCHHHHHHHHHHHEEEEEECCHHEEECCCCCEEEEECCCEEEECCCCCCCCC
IRVILV
EEEEEC
>Mature Secondary Structure 
TDRRPLLRAIFDAAVAAAHPDRILAAHLPPAPSGRIICLAAGKGAAAMAAAAERHYLDT
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LGLEPSRLIGLATTRHGHRVPTRVIEVIEAGHPMPDAAGVRGAETSLALAATATQDDLLL
CCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
VLLSGGGSANWIAPTEDVTLAQKQQATRALLRSGAPIGEVNTVRKHLSRIKGGRLARAGE
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECCCC
HAGQIATLAISDVPRDEPSAIASGPTVPDPTTLADARALVARYGLELDPAVAAALNDERN
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
ESVKAGDGAFAHARFEIIARPRQSLDAAIEVARTAGYEIADLGADLEGEAREVAAAHAQL
CCEECCCCCEEHEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHH
AREARAHGRKLAILSGGELTVTVRGQGRGGPNQEYALALAQQLSDLPDIAALAADTDGAD
HHHHHHCCCEEEEEECCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC
GGAGNADDPAGALIDAATFTQIAALQLDPAAYLADNDATGFFAKTGDLLITGPTLTNVND
CCCCCCCCCCHHHHHHHHHHHEEEEEECCHHEEECCCCCEEEEECCCEEEECCCCCCCCC
IRVILV
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]