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The map label for this gene is yeiE [H]

Identifier: 192290362

GI number: 192290362

Start: 2127941

End: 2128831

Strand: Reverse

Name: yeiE [H]

Synonym: Rpal_1969

Alternate gene names: 192290362

Gene position: 2128831-2127941 (Counterclockwise)

Preceding gene: 192290363

Following gene: 192290361

Centisome position: 37.06

GC content: 66.78

Gene sequence:

>891_bases
ATGACACTCGAGCAGCTCCGCATCTTCATCGCGGTCGCCGAACAGCAGCACATGACCCGCGCCGCAAGCGGACTGAACCT
CACCCAATCGGCCACCAGCGCGGCGATCGCCGCGCTGGAAGCGCGTCACGGCGTCAAGCTGTTCGACCGCGTCGGGCGCG
GCATCGTGCTCACGCAAGCCGGTCGCGACTTTCTCGGCGAGGCCCGCGCGGTGCTCGCCCGTGCCCGCGCCGCCGCACAG
GCTCTCGACGACATCGCCGGCCTGAAACGCGGTTCGCTCAGCGTCGCTGCCAGCCAGACCGCCGGCAATTACTGGCTGCC
GCAGCGGCTGCTGCGATTCCGGCAGCGTTATCCCGGCATTGCGCTGCAACTGACGATCACCAACACCGAGCAGGTCGCCG
CGATCATGCGCGAAGGTCGCGCCGATCTCGGCCTCATCGAAGGCGACGTCGACGACCCACTGCTCAGCGCCACGCCGATC
GGCGGCGACGATCTGGTGATCGTGGTCGGCCGCGACCATCCCTGGCGCTCACTGCAACGCCTGACCGCCGCCAAGCTCAC
CACCACCGGCTGGGTGCTGCGCGAACGCGGCTCCGGCACGCGCGCGATGTTCGAAGCCGCGCTGCAGCGCAGCGGACTTG
CGCTGTCCGATCTCGAGGTGCGCCTCGAATTGCCGTCCAACGAAGCAATCCGGGCTGCGGTCGAAAGCTCCGACTGCGCC
ACCGCGATCTCCGGACTCGTCGCCGCGCCGTCACTCGCCGCCGGCACGTTGTATAGTCTGCGATTCGATCTGCCGCGTCG
CGCATTTCATCTTTTGCGACACAAGGAACACAGCAGCAGTCAGGCTGAGAAAGCACTACTTGCTGAATTGTCGGCAACAT
CTGCGAGCTAA

Upstream 100 bases:

>100_bases
TTGCCGCGCGCGGCCTGCGCCCCGCTTTGCTCGGCCTCACCGCGTCGCTGTTCATTGCCGGCTTCTCGCTGGCGCTGATC
AAACTCACAGGATGGCATGG

Downstream 100 bases:

>100_bases
CCGCGGACGCGAATACCAACGTCGCGGCTGCTAATTCATAGTTCCACGAACAGGAACTCACAGCTTTGTAACTATCCAAA
GAAAACTTGGCTTATTTGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTLEQLRIFIAVAEQQHMTRAASGLNLTQSATSAAIAALEARHGVKLFDRVGRGIVLTQAGRDFLGEARAVLARARAAAQ
ALDDIAGLKRGSLSVAASQTAGNYWLPQRLLRFRQRYPGIALQLTITNTEQVAAIMREGRADLGLIEGDVDDPLLSATPI
GGDDLVIVVGRDHPWRSLQRLTAAKLTTTGWVLRERGSGTRAMFEAALQRSGLALSDLEVRLELPSNEAIRAAVESSDCA
TAISGLVAAPSLAAGTLYSLRFDLPRRAFHLLRHKEHSSSQAEKALLAELSATSAS

Sequences:

>Translated_296_residues
MTLEQLRIFIAVAEQQHMTRAASGLNLTQSATSAAIAALEARHGVKLFDRVGRGIVLTQAGRDFLGEARAVLARARAAAQ
ALDDIAGLKRGSLSVAASQTAGNYWLPQRLLRFRQRYPGIALQLTITNTEQVAAIMREGRADLGLIEGDVDDPLLSATPI
GGDDLVIVVGRDHPWRSLQRLTAAKLTTTGWVLRERGSGTRAMFEAALQRSGLALSDLEVRLELPSNEAIRAAVESSDCA
TAISGLVAAPSLAAGTLYSLRFDLPRRAFHLLRHKEHSSSQAEKALLAELSATSAS
>Mature_295_residues
TLEQLRIFIAVAEQQHMTRAASGLNLTQSATSAAIAALEARHGVKLFDRVGRGIVLTQAGRDFLGEARAVLARARAAAQA
LDDIAGLKRGSLSVAASQTAGNYWLPQRLLRFRQRYPGIALQLTITNTEQVAAIMREGRADLGLIEGDVDDPLLSATPIG
GDDLVIVVGRDHPWRSLQRLTAAKLTTTGWVLRERGSGTRAMFEAALQRSGLALSDLEVRLELPSNEAIRAAVESSDCAT
AISGLVAAPSLAAGTLYSLRFDLPRRAFHLLRHKEHSSSQAEKALLAELSATSAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=34.3642611683849, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=31.7073170731707, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788748, Length=222, Percent_Identity=31.5315315315315, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI145693105, Length=206, Percent_Identity=27.6699029126214, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=201, Percent_Identity=31.8407960199005, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=192, Percent_Identity=34.375, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=24.7011952191235, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082132, Length=270, Percent_Identity=28.1481481481481, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788296, Length=221, Percent_Identity=28.5067873303167, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787530, Length=222, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=29.9539170506912, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786401, Length=172, Percent_Identity=29.0697674418605, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789173, Length=129, Percent_Identity=32.5581395348837, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=175, Percent_Identity=27.4285714285714, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=28.7769784172662, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367136, Length=135, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=30.3448275862069, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787589, Length=164, Percent_Identity=31.0975609756098, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.8965517241379, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788626, Length=143, Percent_Identity=32.8671328671329, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31694; Mature: 31562

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEQLRIFIAVAEQQHMTRAASGLNLTQSATSAAIAALEARHGVKLFDRVGRGIVLTQA
CCHHHHEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECC
GRDFLGEARAVLARARAAAQALDDIAGLKRGSLSVAASQTAGNYWLPQRLLRFRQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCE
ALQLTITNTEQVAAIMREGRADLGLIEGDVDDPLLSATPIGGDDLVIVVGRDHPWRSLQR
EEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
LTAAKLTTTGWVLRERGSGTRAMFEAALQRSGLALSDLEVRLELPSNEAIRAAVESSDCA
HHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEECEEEEEECCCCHHHHHHHCCCHHH
TAISGLVAAPSLAAGTLYSLRFDLPRRAFHLLRHKEHSSSQAEKALLAELSATSAS
HHHHHHHHCCCHHHHHHEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLEQLRIFIAVAEQQHMTRAASGLNLTQSATSAAIAALEARHGVKLFDRVGRGIVLTQA
CHHHHEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECC
GRDFLGEARAVLARARAAAQALDDIAGLKRGSLSVAASQTAGNYWLPQRLLRFRQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCE
ALQLTITNTEQVAAIMREGRADLGLIEGDVDDPLLSATPIGGDDLVIVVGRDHPWRSLQR
EEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH
LTAAKLTTTGWVLRERGSGTRAMFEAALQRSGLALSDLEVRLELPSNEAIRAAVESSDCA
HHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEECEEEEEECCCCHHHHHHHCCCHHH
TAISGLVAAPSLAAGTLYSLRFDLPRRAFHLLRHKEHSSSQAEKALLAELSATSAS
HHHHHHHHCCCHHHHHHEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]