| Definition | Rhodopseudomonas palustris TIE-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011004 |
| Length | 5,744,041 |
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The map label for this gene is fadH [H]
Identifier: 192290358
GI number: 192290358
Start: 2121497
End: 2122369
Strand: Reverse
Name: fadH [H]
Synonym: Rpal_1965
Alternate gene names: 192290358
Gene position: 2122369-2121497 (Counterclockwise)
Preceding gene: 192290361
Following gene: 192290357
Centisome position: 36.95
GC content: 65.52
Gene sequence:
>873_bases ATGTTCACAGATCAGCTTCTCGCCGGCCGTCGCATCCTCGTCACCGGTGGCGGCACCGGCCTCGGCAAGGCGATGGCGGC GCGCTTCCTGCAGCTCGGCGCCGAAGTGCACATCTGCGGCCGCCGCAAGGGCGTGTGCGACGAGACCGCGACCGAACTGA TGGATCAGTACGGCGGCAAGGTGATGACCTACGGCGTCGACATCCGCGACGCCGCGGCAGTCGACCACATGGTCGAGACC ATCTTCGAGAGCGGGCCGCTCACAGACCTGATCAACAACGCGGCGGGAAATTTCATCTCGCGGAGTGAGGATCTCAGCCC GCGCGGCTTCGACGCCGTCGCCAACATCGTGATGCACGGCACGTTCTACGTCACCCACGCGGTCGGCAAGCGCTGGATCG CCGGCGGCCACCGCGGCAACGTGGTGTCGATCACCACCACCTGGGTGCGCAACGGCAGCCCCTATGTGGTGCCGTCGGCG ATGAGCAAGTCGGCGATCCACGCCATGACGATGTCGCTCGCCACCGAATGGGGTAAATACGGCATCCGTCTCAACACCAT TGCGCCGGGCGAAATTCCGACCGAGGGCATGAGCAAGCGGATCAAGCCGGGCGACGAAGCCGGCGCACGCACCATCAAGA TGAACCCGATGGGCCGCGTCGGCACCATGGAGGAGTTGCAGAACCTCGCAACCTTCCTGATCTCCGGCGGCTGCGACTGG ATCAGCGGCGAGACCATCGCCATGGACGGCGCCCAGGGCCTCGCGATGGGCGGCAATTTCTACCAGCTCCGCGACTGGAG CAACGCCGACTGGGATCAGGCCAAGGCCTCGATCAAAGCCCAGAACGAAAAGGACCGCGCGCAGCGGGGGTAA
Upstream 100 bases:
>100_bases TCCCTTCGTTGTTTTGCAGCGCCGCTACAGAAAAGCGTTGTCGAGATTTAGTCAATCGCCTAATTAACGACCAACTTCAA CTTTTCCGGGCGGTTTTCTC
Downstream 100 bases:
>100_bases CGAAGCGCTCGCCGAAACATCCCTCCCCCTTGCGGGGAGGGTGGCCGGCCGTAAGGCCGGTCGGGTGGGGGCGCGCCCCT TGCTCAGTGCCTGGGGCTCC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 290; Mature: 290
Protein sequence:
>290_residues MFTDQLLAGRRILVTGGGTGLGKAMAARFLQLGAEVHICGRRKGVCDETATELMDQYGGKVMTYGVDIRDAAAVDHMVET IFESGPLTDLINNAAGNFISRSEDLSPRGFDAVANIVMHGTFYVTHAVGKRWIAGGHRGNVVSITTTWVRNGSPYVVPSA MSKSAIHAMTMSLATEWGKYGIRLNTIAPGEIPTEGMSKRIKPGDEAGARTIKMNPMGRVGTMEELQNLATFLISGGCDW ISGETIAMDGAQGLAMGGNFYQLRDWSNADWDQAKASIKAQNEKDRAQRG
Sequences:
>Translated_290_residues MFTDQLLAGRRILVTGGGTGLGKAMAARFLQLGAEVHICGRRKGVCDETATELMDQYGGKVMTYGVDIRDAAAVDHMVET IFESGPLTDLINNAAGNFISRSEDLSPRGFDAVANIVMHGTFYVTHAVGKRWIAGGHRGNVVSITTTWVRNGSPYVVPSA MSKSAIHAMTMSLATEWGKYGIRLNTIAPGEIPTEGMSKRIKPGDEAGARTIKMNPMGRVGTMEELQNLATFLISGGCDW ISGETIAMDGAQGLAMGGNFYQLRDWSNADWDQAKASIKAQNEKDRAQRG >Mature_290_residues MFTDQLLAGRRILVTGGGTGLGKAMAARFLQLGAEVHICGRRKGVCDETATELMDQYGGKVMTYGVDIRDAAAVDHMVET IFESGPLTDLINNAAGNFISRSEDLSPRGFDAVANIVMHGTFYVTHAVGKRWIAGGHRGNVVSITTTWVRNGSPYVVPSA MSKSAIHAMTMSLATEWGKYGIRLNTIAPGEIPTEGMSKRIKPGDEAGARTIKMNPMGRVGTMEELQNLATFLISGGCDW ISGETIAMDGAQGLAMGGNFYQLRDWSNADWDQAKASIKAQNEKDRAQRG
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=41.7670682730924, Blast_Score=189, Evalue=2e-48, Organism=Homo sapiens, GI19923817, Length=269, Percent_Identity=31.5985130111524, Blast_Score=137, Evalue=8e-33, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=30.3703703703704, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=25.4980079681275, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=28.6324786324786, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=29.4820717131474, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=31.7073170731707, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=30.6201550387597, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=25.609756097561, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=27.2357723577236, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=25.1937984496124, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=24.6031746031746, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17536025, Length=295, Percent_Identity=40.3389830508475, Blast_Score=199, Evalue=1e-51, Organism=Caenorhabditis elegans, GI17536651, Length=296, Percent_Identity=38.8513513513513, Blast_Score=198, Evalue=2e-51, Organism=Caenorhabditis elegans, GI17561272, Length=273, Percent_Identity=39.5604395604396, Blast_Score=191, Evalue=4e-49, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=26.5873015873016, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562906, Length=283, Percent_Identity=27.5618374558304, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562908, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=24.0875912408759, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=24.812030075188, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=279, Percent_Identity=23.2974910394265, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=23.9700374531835, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17560220, Length=284, Percent_Identity=24.6478873239437, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=28.2352941176471, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=23.9043824701195, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=25.6410256410256, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=24.7191011235955, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=29.2, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=25.390625, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=27.6, Blast_Score=99, Evalue=7e-22, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=27.2357723577236, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI17737361, Length=261, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=24.8, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 31193; Mature: 31193
Theoretical pI: Translated: 7.60; Mature: 7.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 5.2 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 5.2 %Met (Mature Protein) 6.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFTDQLLAGRRILVTGGGTGLGKAMAARFLQLGAEVHICGRRKGVCDETATELMDQYGGK CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCE VMTYGVDIRDAAAVDHMVETIFESGPLTDLINNAAGNFISRSEDLSPRGFDAVANIVMHG EEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH TFYVTHAVGKRWIAGGHRGNVVSITTTWVRNGSPYVVPSAMSKSAIHAMTMSLATEWGKY HHEEEHHHHHHHCCCCCCCCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHC GIRLNTIAPGEIPTEGMSKRIKPGDEAGARTIKMNPMGRVGTMEELQNLATFLISGGCDW CEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCE ISGETIAMDGAQGLAMGGNFYQLRDWSNADWDQAKASIKAQNEKDRAQRG ECCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHCCCCHHHHCCC >Mature Secondary Structure MFTDQLLAGRRILVTGGGTGLGKAMAARFLQLGAEVHICGRRKGVCDETATELMDQYGGK CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCE VMTYGVDIRDAAAVDHMVETIFESGPLTDLINNAAGNFISRSEDLSPRGFDAVANIVMHG EEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH TFYVTHAVGKRWIAGGHRGNVVSITTTWVRNGSPYVVPSAMSKSAIHAMTMSLATEWGKY HHEEEHHHHHHHCCCCCCCCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHC GIRLNTIAPGEIPTEGMSKRIKPGDEAGARTIKMNPMGRVGTMEELQNLATFLISGGCDW CEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCE ISGETIAMDGAQGLAMGGNFYQLRDWSNADWDQAKASIKAQNEKDRAQRG ECCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHHHHCCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]