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The map label for this gene is paaK [H]

Identifier: 192290316

GI number: 192290316

Start: 2071623

End: 2072954

Strand: Reverse

Name: paaK [H]

Synonym: Rpal_1923

Alternate gene names: 192290316

Gene position: 2072954-2071623 (Counterclockwise)

Preceding gene: 192290317

Following gene: 192290313

Centisome position: 36.09

GC content: 65.39

Gene sequence:

>1332_bases
ATGGCCGCAACCGTGCACCAGATCAAGCCGGGTACTTACAATCCGGAGCTCGACGACGCCGAGCGCGCCTCACGCGACGA
GATCGTCGCGCTGCAGACCAAGCGGCTGGCCTGGTCGCTGAAGCACGCTTACGACAACGTCGCGCACTACAAAGCCGCGT
TCGACCGCAAGGGCGTGCACCCGTCCAACTTCCGCCAGCTCTCCGATCTGTCGAAGTTTCCGTTCACGGTGAAGACGGAT
CTGCGCGACAACTACCCGTTCGCGATGTTCGCGGTGCCGCGCGAAAACCTGGTGCGCGTCCACGCGTCGTCCGGCACCAC
CGGCAAGCCGATCGTCGTCGGCTACACGCAGAAGGACATCGAAACCTGGGCCACCGTGATGGCCCGCTCACTGCGCGCCG
CCGGCGCGCGGCGCGGCATGATCATTCACAATTCCTACGGCTACGGCCTGTTCACCGGCGGCTTGGGGGCGCATTACGGC
GGCGAGAAGCTCGGCTGCACTGTCGTTCCGGTGTCCGGCGGCATGACCGAGCGGCAGGTGCAGCTGATCAACGACTTCCG
GCCCGATATCATCACCGTGACGCCGAGCTACATGCTGGCGATTCTCGACGAATTCAAACGCCAGGGCCTCGACCCGCGGC
AGTCCTCGCTGAAATACGGCGTGTTCGGTGCCGAGCCCTGGACCAACGCGATGCGCGCGGAGATCGAGCAGGCGTTCGAC
ATGGATGCGACCGATATCTACGGGCTGTCGGAAGTGATCGGCCCCGGCGTTGCGCAGGAATGCGTCGAGACCAAAGACGG
CCTGCACATCTGGGAGGATCACTTCTATCCGGAAGTGATCGATCCCGAGACCGGCGACGTGCTACCGGATGGCGAGAAAG
GCGAACTGGTGTTCACCTCGCTCACCAAGGAAGCCTTTCCGGTGATCCGCTATCGCACCCGCGACCTGACGCGCCTCCTG
CCCGGCACCGCGCGCCCCGGCATGCGCCGCATGGAAAAGATCACCGGCCGCTCCGACGACATGATCATCCTGCGCGGCGT
CAACGTGTTTCCGACCCAGATCGAGGAAGTGCTGCTCGGCACCGACTGGTGCGGCGGCCACTTCATCATCGAGCTGACCC
GCGAGGGGCGGATGGACGAGATGACGGTGCTGGCCGAAGCCCGGCCGGAGAGCTGGGACGGCGCCGGTCTGGTGCCGCAC
GCCGAGCGGGTCGCCGCCTACATCAAGAACACCATCGGCATCTCGACCACCATCAAAGTAGTGCCGCCCGACACCCTGGA
GCGCTCGCTCGGCAAGGCCCGGCGGGTGTTCGACAAGCGGCCGAAGGGCTAG

Upstream 100 bases:

>100_bases
GCCAGACGGTGATCGCCGAATTCCGCGGCCATTCGCGCTCGATCGGCGGCACGCTGGTGCCACCGCAACAACCAGACCCA
CGCTGAGGAAGGAGACGGCG

Downstream 100 bases:

>100_bases
CGCGCGCTACAGCGCCTTGCGGAAGGTGAGGTTGATCCGCTGCCGGCCGAGCAGCGGATGCTCGCCGTCCTTCAGCGTCA
GCACGCCGTGATACACCAGC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAATVHQIKPGTYNPELDDAERASRDEIVALQTKRLAWSLKHAYDNVAHYKAAFDRKGVHPSNFRQLSDLSKFPFTVKTD
LRDNYPFAMFAVPRENLVRVHASSGTTGKPIVVGYTQKDIETWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYG
GEKLGCTVVPVSGGMTERQVQLINDFRPDIITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFD
MDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVIDPETGDVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRLL
PGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARPESWDGAGLVPH
AERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVFDKRPKG

Sequences:

>Translated_443_residues
MAATVHQIKPGTYNPELDDAERASRDEIVALQTKRLAWSLKHAYDNVAHYKAAFDRKGVHPSNFRQLSDLSKFPFTVKTD
LRDNYPFAMFAVPRENLVRVHASSGTTGKPIVVGYTQKDIETWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYG
GEKLGCTVVPVSGGMTERQVQLINDFRPDIITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFD
MDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVIDPETGDVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRLL
PGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARPESWDGAGLVPH
AERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVFDKRPKG
>Mature_442_residues
AATVHQIKPGTYNPELDDAERASRDEIVALQTKRLAWSLKHAYDNVAHYKAAFDRKGVHPSNFRQLSDLSKFPFTVKTDL
RDNYPFAMFAVPRENLVRVHASSGTTGKPIVVGYTQKDIETWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYGG
EKLGCTVVPVSGGMTERQVQLINDFRPDIITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFDM
DATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVIDPETGDVLPDGEKGELVFTSLTKEAFPVIRYRTRDLTRLLP
GTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLGTDWCGGHFIIELTREGRMDEMTVLAEARPESWDGAGLVPHA
ERVAAYIKNTIGISTTIKVVPPDTLERSLGKARRVFDKRPKG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=434, Percent_Identity=60.1382488479263, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49346; Mature: 49215

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATVHQIKPGTYNPELDDAERASRDEIVALQTKRLAWSLKHAYDNVAHYKAAFDRKGVH
CCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSNFRQLSDLSKFPFTVKTDLRDNYPFAMFAVPRENLVRVHASSGTTGKPIVVGYTQKDI
HHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEECCHHHH
ETWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYGGEKLGCTVVPVSGGMTERQV
HHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCHHHH
QLINDFRPDIITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFD
HHHHHCCCCEEEECHHHHHHHHHHHHHCCCCCCHHCCEECCCCCCCHHHHHHHHHHHHHC
MDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVIDPETGDVLPDGEKGELVFTS
CCCHHHCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCEEEEE
LTKEAFPVIRYRTRDLTRLLPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHC
TDWCGGHFIIELTREGRMDEMTVLAEARPESWDGAGLVPHAERVAAYIKNTIGISTTIKV
CCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEE
VPPDTLERSLGKARRVFDKRPKG
ECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AATVHQIKPGTYNPELDDAERASRDEIVALQTKRLAWSLKHAYDNVAHYKAAFDRKGVH
CCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PSNFRQLSDLSKFPFTVKTDLRDNYPFAMFAVPRENLVRVHASSGTTGKPIVVGYTQKDI
HHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEECCHHHH
ETWATVMARSLRAAGARRGMIIHNSYGYGLFTGGLGAHYGGEKLGCTVVPVSGGMTERQV
HHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCHHHH
QLINDFRPDIITVTPSYMLAILDEFKRQGLDPRQSSLKYGVFGAEPWTNAMRAEIEQAFD
HHHHHCCCCEEEECHHHHHHHHHHHHHCCCCCCHHCCEECCCCCCCHHHHHHHHHHHHHC
MDATDIYGLSEVIGPGVAQECVETKDGLHIWEDHFYPEVIDPETGDVLPDGEKGELVFTS
CCCHHHCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCEEEEE
LTKEAFPVIRYRTRDLTRLLPGTARPGMRRMEKITGRSDDMIILRGVNVFPTQIEEVLLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHC
TDWCGGHFIIELTREGRMDEMTVLAEARPESWDGAGLVPHAERVAAYIKNTIGISTTIKV
CCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEE
VPPDTLERSLGKARRVFDKRPKG
ECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]