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The map label for this gene is yajO [H]

Identifier: 192290245

GI number: 192290245

Start: 1986198

End: 1987211

Strand: Reverse

Name: yajO [H]

Synonym: Rpal_1849

Alternate gene names: 192290245

Gene position: 1987211-1986198 (Counterclockwise)

Preceding gene: 192290246

Following gene: 192290244

Centisome position: 34.6

GC content: 67.55

Gene sequence:

>1014_bases
ATGGACTATCGTTCGCTCGGCCGCAGCGGCCTGAAAGTCTCGCCGCTGTGCCTCGGCACCATGATGTTCGGCGGCGCGAC
CGACGAGCCGACCTCGGCACGGATTATCGATAAGGCGCGCGACGCCGGGATCAATTTCATCGACACCGCCGACGTCTATT
CAATGGGCGCATCCGAACAGGTGGTCGGCCGCGCGATCGCGGCGCATCGCGAGCACTGGATCCTCGCCACCAAGGTCGCC
AACCCGATGGGCGACGGCCCGAACCATGCCGGGCTGTCGCGCCGCCGCGTGCTTCAGGCTGCCGACGACAGCCTGAAGCG
CCTCGGCACCGACTGGATCGACATCCATTATCTGCACCGCGAGGACCACGCGACGCCGCTCGATGAAACGGTACGGGCGA
TCGGCGACCTGATCCGCGCCGGCAAGATCCGGTACTTCGGCGTGTCGAACTATCGCGCCTGGCGCGTCGCCGAGATCTGC
AACATCTGCGACCGCCTCGGCATCGACCGCCCGGTGGTCAGCCAGCCGTATTACAACGCCATGAACCGGATGCCGGAGGT
CGAGCACATCCCGGCCTGCGGATTCTACGGCCTCGGTATCGTCCCCTACTCGCCGCTGGCACGCGGCGTCCTGACTGGCA
AATACGCACCCGACACTGAGCCGGACAAGGACAGCCGCGCTGGCCGCGCCGACAAGCGGATGCTGCAGACCGAATGGCGG
CCGGAATCGCTGAAGCTGGCGCAGCAGATCCGAGCCCACGCCGAGGCCAAGGGCGCCACCGCCGTCCAGTTTGCGGTCGG
CTGGGTGCTGAACAACGCGCTGGTGACCTCGGTGATCGCCGGCCCACGCACCGAGCAGCAATGGGACGATTACGTTCGGG
CGCTCGACTATCGCTTCACCGCTGACGACGAGGCGCTGGTCGACGCCCTGGTGGCGAGCGGCCATCCCTCCACGCCCGGC
TACAACGACCCGGCCTACCCGATCGAGGGTCGCACGGTGCGCCACGCCGGCTGA

Upstream 100 bases:

>100_bases
ACGTCTTCAAGCGCCCGCAAAGGCGTGGATGGCCGGGACAAGCCCGGCCATGACGGATGAGAACCGGGATCGATGCCACT
ATCAAAAGACGAGGCCCCCC

Downstream 100 bases:

>100_bases
CCGCCGGCGGCCGCCCCGGCCAAAGTTGCGGCCGATCAAGCCGATCCGCTGCGCCGCACCGTAGTGTCGCCGCATCACGC
GGCCGCGCGATCGCTATTCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDYRSLGRSGLKVSPLCLGTMMFGGATDEPTSARIIDKARDAGINFIDTADVYSMGASEQVVGRAIAAHREHWILATKVA
NPMGDGPNHAGLSRRRVLQAADDSLKRLGTDWIDIHYLHREDHATPLDETVRAIGDLIRAGKIRYFGVSNYRAWRVAEIC
NICDRLGIDRPVVSQPYYNAMNRMPEVEHIPACGFYGLGIVPYSPLARGVLTGKYAPDTEPDKDSRAGRADKRMLQTEWR
PESLKLAQQIRAHAEAKGATAVQFAVGWVLNNALVTSVIAGPRTEQQWDDYVRALDYRFTADDEALVDALVASGHPSTPG
YNDPAYPIEGRTVRHAG

Sequences:

>Translated_337_residues
MDYRSLGRSGLKVSPLCLGTMMFGGATDEPTSARIIDKARDAGINFIDTADVYSMGASEQVVGRAIAAHREHWILATKVA
NPMGDGPNHAGLSRRRVLQAADDSLKRLGTDWIDIHYLHREDHATPLDETVRAIGDLIRAGKIRYFGVSNYRAWRVAEIC
NICDRLGIDRPVVSQPYYNAMNRMPEVEHIPACGFYGLGIVPYSPLARGVLTGKYAPDTEPDKDSRAGRADKRMLQTEWR
PESLKLAQQIRAHAEAKGATAVQFAVGWVLNNALVTSVIAGPRTEQQWDDYVRALDYRFTADDEALVDALVASGHPSTPG
YNDPAYPIEGRTVRHAG
>Mature_337_residues
MDYRSLGRSGLKVSPLCLGTMMFGGATDEPTSARIIDKARDAGINFIDTADVYSMGASEQVVGRAIAAHREHWILATKVA
NPMGDGPNHAGLSRRRVLQAADDSLKRLGTDWIDIHYLHREDHATPLDETVRAIGDLIRAGKIRYFGVSNYRAWRVAEIC
NICDRLGIDRPVVSQPYYNAMNRMPEVEHIPACGFYGLGIVPYSPLARGVLTGKYAPDTEPDKDSRAGRADKRMLQTEWR
PESLKLAQQIRAHAEAKGATAVQFAVGWVLNNALVTSVIAGPRTEQQWDDYVRALDYRFTADDEALVDALVASGHPSTPG
YNDPAYPIEGRTVRHAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=32.6860841423948, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI27436964, Length=309, Percent_Identity=32.0388349514563, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=32.0388349514563, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=32.5732899022801, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=31.7152103559871, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=30.03003003003, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI223718702, Length=226, Percent_Identity=38.9380530973451, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI41152114, Length=201, Percent_Identity=39.3034825870647, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI41327764, Length=212, Percent_Identity=40.5660377358491, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI223718708, Length=179, Percent_Identity=37.4301675977654, Blast_Score=95, Evalue=7e-20,
Organism=Escherichia coli, GI87081735, Length=306, Percent_Identity=38.562091503268, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=33.434650455927, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=31.3953488372093, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788070, Length=322, Percent_Identity=29.5031055900621, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788081, Length=183, Percent_Identity=32.2404371584699, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI212645785, Length=319, Percent_Identity=23.5109717868339, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=325, Percent_Identity=29.5384615384615, Blast_Score=152, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323998, Length=340, Percent_Identity=26.7647058823529, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=26.3975155279503, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=313, Percent_Identity=24.6006389776358, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=25.4681647940075, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=31.4102564102564, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640980, Length=316, Percent_Identity=24.0506329113924, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=316, Percent_Identity=24.0506329113924, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24646155, Length=162, Percent_Identity=36.4197530864198, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=30.4932735426009, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37114; Mature: 37114

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRSLGRSGLKVSPLCLGTMMFGGATDEPTSARIIDKARDAGINFIDTADVYSMGASEQ
CCHHHHCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECHHHHHCCCHHH
VVGRAIAAHREHWILATKVANPMGDGPNHAGLSRRRVLQAADDSLKRLGTDWIDIHYLHR
HHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
EDHATPLDETVRAIGDLIRAGKIRYFGVSNYRAWRVAEICNICDRLGIDRPVVSQPYYNA
CCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MNRMPEVEHIPACGFYGLGIVPYSPLARGVLTGKYAPDTEPDKDSRAGRADKRMLQTEWR
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PESLKLAQQIRAHAEAKGATAVQFAVGWVLNNALVTSVIAGPRTEQQWDDYVRALDYRFT
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
ADDEALVDALVASGHPSTPGYNDPAYPIEGRTVRHAG
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MDYRSLGRSGLKVSPLCLGTMMFGGATDEPTSARIIDKARDAGINFIDTADVYSMGASEQ
CCHHHHCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECHHHHHCCCHHH
VVGRAIAAHREHWILATKVANPMGDGPNHAGLSRRRVLQAADDSLKRLGTDWIDIHYLHR
HHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
EDHATPLDETVRAIGDLIRAGKIRYFGVSNYRAWRVAEICNICDRLGIDRPVVSQPYYNA
CCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MNRMPEVEHIPACGFYGLGIVPYSPLARGVLTGKYAPDTEPDKDSRAGRADKRMLQTEWR
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PESLKLAQQIRAHAEAKGATAVQFAVGWVLNNALVTSVIAGPRTEQQWDDYVRALDYRFT
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
ADDEALVDALVASGHPSTPGYNDPAYPIEGRTVRHAG
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]