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The map label for this gene is cusB [H]

Identifier: 192290003

GI number: 192290003

Start: 1717605

End: 1718999

Strand: Reverse

Name: cusB [H]

Synonym: Rpal_1604

Alternate gene names: 192290003

Gene position: 1718999-1717605 (Counterclockwise)

Preceding gene: 192290004

Following gene: 192290002

Centisome position: 29.93

GC content: 66.38

Gene sequence:

>1395_bases
ATGACCAAGCTGCGCTCACCCTCACTGCTGTTTCTGATCGGACTCTGTCTCGCGTCGCCTGCCGCGGCTGACGAGCGATC
GCCGCTGTACTACCGCGATCCATCCGGCGCGCCGCGCTGGTCGGCGGTGCCGAAGGCCGATGCGCAAGGCCGCGCTTATC
TGCCGGTGTATGAGGCCGACGAGCCCTCTGCGCAGCCGGCGCCGAAGCCCGCGGCCGATCCCGCCCGCAAGATCCTGTAC
TACCGCAATCCGATGGGGCTGCCCGACATCTCGAAGGTGCCGAAGAAGGACTCGATGGGGATGGACTACGTCCCCGTCTA
TGAGGGCGAGGACAGTGCGGACGGCACGGTGAAGCTGTCGCCCGGCAAGATCCAGCGCAGCGGCGTCAAATCCGAGCCCG
CCGAACGCCGCGCCCTGCATGTGATGGTGAAGGCGCCGGGCGTGATCCAGCTCGACGAGCGCCGCGTCTCGGTGATCGCG
ATGCGCAGCGAAAGCTTCGTCGAGAAGATCGCCGACGTCACCACCGGCAGCGTCGTCAAAGCCGGGCAGCCGCTGATGCA
GATCTACAGCTCGGCGATCGCCTCGGCCGCCGCCGAGTATCTGTCGACGATCACCTCGAAGAATAGCAGCACGATCGAAG
CCTTCGGCCGCGGCTCGCGGCAGCGACTGGTCAATCTCGACGTACCCGACGAGACCATCGCCGAATTGGAGCGGACGCGG
ACCGCGCCGGTGACGGTGCAATGGCGCGCGCCGCGCGACGGCATTGTGCTGGAGCGCAACGCGATCGACGGCATGCGCGC
CAATGTCGGTGACGTGCTGTTCCGGATCGCCGACATCTCGACGGTGTGGGCCCTCGTCGACGTCGCCGAACGCGATCTCG
GCACACTCTCGGTGGGTCAGAAGGTGACGATCCGAGCCCGAGCCTTCCCTGATCGCGCGCGCTCTGGAACGATCGCGGTG
ATCTATCCGCAGGTCAATCGCGATACGCGCACTACGCGGCTACGCGTCGAACTCGCCAATCCGGATCTGAAGCTGTTGCC
GGACATGTATGTCGATGCCGAGATCGACATCGCCGGCGATGCACCGGTGCTGACGATTCCAACCTCCGCCGTGCTCGACA
ACGGCAGCCGGCGCATCGTGCTGGTGGACAAGGGCGACGGCCGGTTCGAGCCGCGGACGGTGACACTCGGACGCCGCGGC
GACGGCGTCGTCGAGGTCAAACACGGCATCGACGAAGGCGAGGCGGTGGTCACCTCCGCCAACTTCCTGATCGACGCCGA
GAGCAATCTGAAGGCCGCGCTAAAGGGCTTTGCCGACGGAGCGAACGCCCCCAGCAACGAGCCGCAAGCTTCGTCGCACA
ATCACGCACACGACCACGCCGGAGCCCAGCCATGA

Upstream 100 bases:

>100_bases
GGCGTTCAAATAGGCCAGCGCGGCGCCGCAGCCGCGGCGCCGCCGTCCTTCCTATCTCCCGAATTCGGATGCGCCCTCGC
GGCGCGCGACGGTGCACGTC

Downstream 100 bases:

>100_bases
TTGCCCGGATCATCGCCTGGTCGGCGCGCAATCTGCTGCTGGTGCTGTTCGGCACGGGTTTCGCCGTAGCCGCGGGTCTC
TACGCCCTGCTGCATCTGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTKLRSPSLLFLIGLCLASPAAADERSPLYYRDPSGAPRWSAVPKADAQGRAYLPVYEADEPSAQPAPKPAADPARKILY
YRNPMGLPDISKVPKKDSMGMDYVPVYEGEDSADGTVKLSPGKIQRSGVKSEPAERRALHVMVKAPGVIQLDERRVSVIA
MRSESFVEKIADVTTGSVVKAGQPLMQIYSSAIASAAAEYLSTITSKNSSTIEAFGRGSRQRLVNLDVPDETIAELERTR
TAPVTVQWRAPRDGIVLERNAIDGMRANVGDVLFRIADISTVWALVDVAERDLGTLSVGQKVTIRARAFPDRARSGTIAV
IYPQVNRDTRTTRLRVELANPDLKLLPDMYVDAEIDIAGDAPVLTIPTSAVLDNGSRRIVLVDKGDGRFEPRTVTLGRRG
DGVVEVKHGIDEGEAVVTSANFLIDAESNLKAALKGFADGANAPSNEPQASSHNHAHDHAGAQP

Sequences:

>Translated_464_residues
MTKLRSPSLLFLIGLCLASPAAADERSPLYYRDPSGAPRWSAVPKADAQGRAYLPVYEADEPSAQPAPKPAADPARKILY
YRNPMGLPDISKVPKKDSMGMDYVPVYEGEDSADGTVKLSPGKIQRSGVKSEPAERRALHVMVKAPGVIQLDERRVSVIA
MRSESFVEKIADVTTGSVVKAGQPLMQIYSSAIASAAAEYLSTITSKNSSTIEAFGRGSRQRLVNLDVPDETIAELERTR
TAPVTVQWRAPRDGIVLERNAIDGMRANVGDVLFRIADISTVWALVDVAERDLGTLSVGQKVTIRARAFPDRARSGTIAV
IYPQVNRDTRTTRLRVELANPDLKLLPDMYVDAEIDIAGDAPVLTIPTSAVLDNGSRRIVLVDKGDGRFEPRTVTLGRRG
DGVVEVKHGIDEGEAVVTSANFLIDAESNLKAALKGFADGANAPSNEPQASSHNHAHDHAGAQP
>Mature_463_residues
TKLRSPSLLFLIGLCLASPAAADERSPLYYRDPSGAPRWSAVPKADAQGRAYLPVYEADEPSAQPAPKPAADPARKILYY
RNPMGLPDISKVPKKDSMGMDYVPVYEGEDSADGTVKLSPGKIQRSGVKSEPAERRALHVMVKAPGVIQLDERRVSVIAM
RSESFVEKIADVTTGSVVKAGQPLMQIYSSAIASAAAEYLSTITSKNSSTIEAFGRGSRQRLVNLDVPDETIAELERTRT
APVTVQWRAPRDGIVLERNAIDGMRANVGDVLFRIADISTVWALVDVAERDLGTLSVGQKVTIRARAFPDRARSGTIAVI
YPQVNRDTRTTRLRVELANPDLKLLPDMYVDAEIDIAGDAPVLTIPTSAVLDNGSRRIVLVDKGDGRFEPRTVTLGRRGD
GVVEVKHGIDEGEAVVTSANFLIDAESNLKAALKGFADGANAPSNEPQASSHNHAHDHAGAQP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=396, Percent_Identity=29.2929292929293, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50003; Mature: 49872

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLRSPSLLFLIGLCLASPAAADERSPLYYRDPSGAPRWSAVPKADAQGRAYLPVYEAD
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECC
EPSAQPAPKPAADPARKILYYRNPMGLPDISKVPKKDSMGMDYVPVYEGEDSADGTVKLS
CCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCEEEEC
PGKIQRSGVKSEPAERRALHVMVKAPGVIQLDERRVSVIAMRSESFVEKIADVTTGSVVK
CCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHHHHHHHHCCCCCHHH
AGQPLMQIYSSAIASAAAEYLSTITSKNSSTIEAFGRGSRQRLVNLDVPDETIAELERTR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHCC
TAPVTVQWRAPRDGIVLERNAIDGMRANVGDVLFRIADISTVWALVDVAERDLGTLSVGQ
CCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
KVTIRARAFPDRARSGTIAVIYPQVNRDTRTTRLRVELANPDLKLLPDMYVDAEIDIAGD
EEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEECCCEEECEEEEECCC
APVLTIPTSAVLDNGSRRIVLVDKGDGRFEPRTVTLGRRGDGVVEVKHGIDEGEAVVTSA
CCEEEECCHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEE
NFLIDAESNLKAALKGFADGANAPSNEPQASSHNHAHDHAGAQP
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKLRSPSLLFLIGLCLASPAAADERSPLYYRDPSGAPRWSAVPKADAQGRAYLPVYEAD
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECC
EPSAQPAPKPAADPARKILYYRNPMGLPDISKVPKKDSMGMDYVPVYEGEDSADGTVKLS
CCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCEEEEC
PGKIQRSGVKSEPAERRALHVMVKAPGVIQLDERRVSVIAMRSESFVEKIADVTTGSVVK
CCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHHHHHHHHCCCCCHHH
AGQPLMQIYSSAIASAAAEYLSTITSKNSSTIEAFGRGSRQRLVNLDVPDETIAELERTR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHCC
TAPVTVQWRAPRDGIVLERNAIDGMRANVGDVLFRIADISTVWALVDVAERDLGTLSVGQ
CCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
KVTIRARAFPDRARSGTIAVIYPQVNRDTRTTRLRVELANPDLKLLPDMYVDAEIDIAGD
EEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEECCCEEECEEEEECCC
APVLTIPTSAVLDNGSRRIVLVDKGDGRFEPRTVTLGRRGDGVVEVKHGIDEGEAVVTSA
CCEEEECCHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCEEEEEE
NFLIDAESNLKAALKGFADGANAPSNEPQASSHNHAHDHAGAQP
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]