Click here to switch to the map view.

The map label for this gene is aprE [H]

Identifier: 192289965

GI number: 192289965

Start: 1656794

End: 1658116

Strand: Reverse

Name: aprE [H]

Synonym: Rpal_1562

Alternate gene names: 192289965

Gene position: 1658116-1656794 (Counterclockwise)

Preceding gene: 192289966

Following gene: 192289947

Centisome position: 28.87

GC content: 64.47

Gene sequence:

>1323_bases
ATGACCGCATCTGCGATGCCCAAGCCTCGCCACAGCGACCCGTTCCGCGATATCTGGCGCGCGGCCGGTCTCGGCATTGC
CACGTTGGTGATCGTCGCCTCGACGGCCGGCGTCTGGGCCATGACGGCGCCGCTCGCCAGCGCCGTGATCGCGCCGGCTC
AGGTGGTGGTCGATAGCAACGTCCGCCGCGTCCAGCACCCGACGGGCGGTGTCGTCGCCGAAATCTACGTCAACGACGGC
GATGAGGTTCGCGCCGGAGACATGCTGGCCCGCCTCGACGAGACGATGCCGCGCGCCAACCTGGCGTTGATCGAGAACCA
ACTCAACCAGTTGGTGGTTCGTCGCGCCCGGCTGCAATCCGAGCAGAACGGCAACGATACGCTGGCGTTGCCCGCCGAGA
TCGCCGCCCGCCGCAACGTTGCGGCGATCGCCGAAATGATCGATGGCGAAACGACGCTGTTCGTCCGGCGGCGCGACGCG
ATCAGCGGCCAGCAATCGCAGCTCCGCGAACGCAAGGCGCAGATCGCGGACGAGATCCGCGGCCTCGAAGCGCAGATCGT
CTCGAAGCGCGAACAGATCCGTTGGATCCAGACTGAGCTGGAAGGCGTGCGCCAGCTTTATGAGAAAAACCTAGTTCCCT
ATGCCCGGCTCACGGCGCTTGAGCGTGAGGCATCCCGGCTGACCGGTGAAGAAGGACAATTGATCGCCGAGATCGCCCGC
GCCAGGGGCCGGATCACCGAGACCGAGCTTCAGATCCTTCAATTAGTTCAGGATCAGCGCCGCGAGGTGGCGACCGAACT
GCGCGACGTCGAGACCAAGATCACAGACCTCGGCGAACGCCGCATCGCCGCATTGGACCAATTGGAACGCGTTGTCCTGC
GCGCGCCGCAGGATGGCCTGGTGCATCAAAAATCAGTCCACACCGTCGGCGGCGTGATCAGTGCGGGCGAACAGCTGATG
CTGATCGTACCGAAAGATTCGCTGGTGGTTGAAGCCAAGGTCGATCCGCAGATGATCGACCGGCTCAAGGTCGGACAACC
CGCCAAGCTTCGGTTCAGCGCATTCGACGCCGCCGTGACTCCCGAACTCGACGGCACACTGACCCGAGTCGCTGCCGACC
TGACCAAGGATCAGCAATCCGGCGCGGCGTACTACGTCGCGCGGATCAGCCTCACGCCCAGCGAACTGGGGAAGCTCGAT
GGCAAGGCGCTGGTCCCCGGCATGCCGGTCGAAGCCTTCATCCAGAATGGCATGCGGACGGCGTTCGCCTATCTCCGCAA
GCCTCTCGAAGACCAACTCGCCCGCGCGATGCGACAGAAATAG

Upstream 100 bases:

>100_bases
AAGTCACTCGCGGCTCATCCTGCGGCAAGCGGTGCGGCGCTTCAGGCCGTGCCGGACCCGCGTTCGGTACCGGCCGCAGC
CGTCAGTTGAGGACGCTCCC

Downstream 100 bases:

>100_bases
CAACGGTCTGAATCGCGATCGGTGTTCACGGACATCTGGATCGAGACGTTCACCTGGAGCTCTGGAGTTCAGGCTGAGCG
ACCAGGTGAAAAGGCTGAGA

Product: type I secretion membrane fusion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTASAMPKPRHSDPFRDIWRAAGLGIATLVIVASTAGVWAMTAPLASAVIAPAQVVVDSNVRRVQHPTGGVVAEIYVNDG
DEVRAGDMLARLDETMPRANLALIENQLNQLVVRRARLQSEQNGNDTLALPAEIAARRNVAAIAEMIDGETTLFVRRRDA
ISGQQSQLRERKAQIADEIRGLEAQIVSKREQIRWIQTELEGVRQLYEKNLVPYARLTALEREASRLTGEEGQLIAEIAR
ARGRITETELQILQLVQDQRREVATELRDVETKITDLGERRIAALDQLERVVLRAPQDGLVHQKSVHTVGGVISAGEQLM
LIVPKDSLVVEAKVDPQMIDRLKVGQPAKLRFSAFDAAVTPELDGTLTRVAADLTKDQQSGAAYYVARISLTPSELGKLD
GKALVPGMPVEAFIQNGMRTAFAYLRKPLEDQLARAMRQK

Sequences:

>Translated_440_residues
MTASAMPKPRHSDPFRDIWRAAGLGIATLVIVASTAGVWAMTAPLASAVIAPAQVVVDSNVRRVQHPTGGVVAEIYVNDG
DEVRAGDMLARLDETMPRANLALIENQLNQLVVRRARLQSEQNGNDTLALPAEIAARRNVAAIAEMIDGETTLFVRRRDA
ISGQQSQLRERKAQIADEIRGLEAQIVSKREQIRWIQTELEGVRQLYEKNLVPYARLTALEREASRLTGEEGQLIAEIAR
ARGRITETELQILQLVQDQRREVATELRDVETKITDLGERRIAALDQLERVVLRAPQDGLVHQKSVHTVGGVISAGEQLM
LIVPKDSLVVEAKVDPQMIDRLKVGQPAKLRFSAFDAAVTPELDGTLTRVAADLTKDQQSGAAYYVARISLTPSELGKLD
GKALVPGMPVEAFIQNGMRTAFAYLRKPLEDQLARAMRQK
>Mature_439_residues
TASAMPKPRHSDPFRDIWRAAGLGIATLVIVASTAGVWAMTAPLASAVIAPAQVVVDSNVRRVQHPTGGVVAEIYVNDGD
EVRAGDMLARLDETMPRANLALIENQLNQLVVRRARLQSEQNGNDTLALPAEIAARRNVAAIAEMIDGETTLFVRRRDAI
SGQQSQLRERKAQIADEIRGLEAQIVSKREQIRWIQTELEGVRQLYEKNLVPYARLTALEREASRLTGEEGQLIAEIARA
RGRITETELQILQLVQDQRREVATELRDVETKITDLGERRIAALDQLERVVLRAPQDGLVHQKSVHTVGGVISAGEQLML
IVPKDSLVVEAKVDPQMIDRLKVGQPAKLRFSAFDAAVTPELDGTLTRVAADLTKDQQSGAAYYVARISLTPSELGKLDG
KALVPGMPVEAFIQNGMRTAFAYLRKPLEDQLARAMRQK

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48453; Mature: 48322

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAMPKPRHSDPFRDIWRAAGLGIATLVIVASTAGVWAMTAPLASAVIAPAQVVVDSN
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHEECCC
VRRVQHPTGGVVAEIYVNDGDEVRAGDMLARLDETMPRANLALIENQLNQLVVRRARLQS
CHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
EQNGNDTLALPAEIAARRNVAAIAEMIDGETTLFVRRRDAISGQQSQLRERKAQIADEIR
CCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHHHHHHHHHHHHH
GLEAQIVSKREQIRWIQTELEGVRQLYEKNLVPYARLTALEREASRLTGEEGQLIAEIAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
ARGRITETELQILQLVQDQRREVATELRDVETKITDLGERRIAALDQLERVVLRAPQDGL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VHQKSVHTVGGVISAGEQLMLIVPKDSLVVEAKVDPQMIDRLKVGQPAKLRFSAFDAAVT
CCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEEEHHCCCCC
PELDGTLTRVAADLTKDQQSGAAYYVARISLTPSELGKLDGKALVPGMPVEAFIQNGMRT
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHCCCCCCCCCCCCHHHHHHCCHHH
AFAYLRKPLEDQLARAMRQK
HHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TASAMPKPRHSDPFRDIWRAAGLGIATLVIVASTAGVWAMTAPLASAVIAPAQVVVDSN
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHEECCC
VRRVQHPTGGVVAEIYVNDGDEVRAGDMLARLDETMPRANLALIENQLNQLVVRRARLQS
CHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
EQNGNDTLALPAEIAARRNVAAIAEMIDGETTLFVRRRDAISGQQSQLRERKAQIADEIR
CCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHHHHHHHHHHHHH
GLEAQIVSKREQIRWIQTELEGVRQLYEKNLVPYARLTALEREASRLTGEEGQLIAEIAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
ARGRITETELQILQLVQDQRREVATELRDVETKITDLGERRIAALDQLERVVLRAPQDGL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VHQKSVHTVGGVISAGEQLMLIVPKDSLVVEAKVDPQMIDRLKVGQPAKLRFSAFDAAVT
CCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHCCCCCCEEEEEHHCCCCC
PELDGTLTRVAADLTKDQQSGAAYYVARISLTPSELGKLDGKALVPGMPVEAFIQNGMRT
CCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHCCCCCCCCCCCCHHHHHHCCHHH
AFAYLRKPLEDQLARAMRQK
HHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]