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The map label for this gene is mdtA [H]

Identifier: 192289934

GI number: 192289934

Start: 1613699

End: 1614874

Strand: Reverse

Name: mdtA [H]

Synonym: Rpal_1530

Alternate gene names: 192289934

Gene position: 1614874-1613699 (Counterclockwise)

Preceding gene: 192289943

Following gene: 192289933

Centisome position: 28.11

GC content: 63.01

Gene sequence:

>1176_bases
ATGCGCAAATCTGTCATTCTCGCTTCCACGCTGGCCGGAGCTGCGCTTGCGGCGAGCCTTTGGTACATCCGACAAGACGA
GTCCCTCGCCGCATCAGCCGTGGTGCGGGTGCCGAGCGCAGCGGTACCGGTGATTACCGCGAGGGTTGCTCGCAGCGATG
TGCCGGTCTATTTGCGCGGCATCGGGACCGTCGTCGCCTACAACACCGATGTGGTCCGCAGTCAGATCCAGGGCCAGCTC
ACTGCGATCGATTTCACTGAAGGGCAATTCGTCAAAGCCGGCGATATGCTGGCGCAGATCGATCCGCGTCCCTATCAGGC
GCAGATCGCACAGCTGACCGCCAATCGCGACCGCGACGTTGCGCACCTCGCCAACGCGAAGGCTAACCTCGATCGAGATA
CTCAGCTGGGCGACAAGGGCTTCGCCAGCACCCAGGCGATCGAGACCCAGCAGGCGAAGGTCTCTCAGCTTCAGGCGGCC
GTGGAGGCCGACCAGGCGGCGATCGATCAGGCCAACGTTCAGCTCGGCTACACCCGCCTGACCTCGCCGATCCCCGGCAT
CACTGGCGTTCGGCAAATCGATATCGGCAATATCATTCATACGACCGATCCCAACGGTTTGGTGGTGGTGACCCAGATCG
AGCCGATCTCCGTCCTGTTCGCGTTACCTGAAGCCGATCTACCGCGGATTCAGACTCAGATGGCAAAGGGCTCTCTCCCA
GTGATCGCCTATACTCAAGACGGCCGGACCAGGCTTGACGAAGGCAAGCTTCTGCTCGTCAACAACCAGATCGACCAGGC
GACCGGCACCGTGCAGCTCAAAGCGGAGTTCGCCAACACCGAGCATCGGCTCTGGCCAGGCCAGCTGATCACCGTCAATC
TGCTGCTGACGACGCGAAAGAATGCCGTCACCGTCGCGGGCTCCGCCGTGCAGCAGGGGCCGAATGGCTCCTACATCTTC
GTGGTCTCGCCGTCGGGAACCGCCGAGATGCGGCCTGTGACAGTCGGTCAAATCAGCCGTGGACAGGCGTTGATAGACTC
CGGCCTCGCCGGCGACGAGACGGTGGTGGTCGACGGCCAATATCGACTGCAGCAAGGCAGCCGCGTCGAGCCGCTGCACG
GCAAGGCGGCGCAGGAAGCGGATCTGCAGAGCGCAGTCCAGGACGCGCTGCCGTGA

Upstream 100 bases:

>100_bases
CATCGCTTGCTCCAACTTCTGGCGTCGAAGTCGCGGCTCGTACTTCGGGCAGCGGGACGTCGCGCCGTGAATTCGTCAGG
CTCGCAAGGACGTCTCGACC

Downstream 100 bases:

>100_bases
ACCTCTCGGCCCCCTTCATCAGCCGACCGATCGCGACCTCGCTGCTGATGCTCGGCCTGCTGCTGTGCGGCCTCGCGACT
TATCGACTTCTCCCTGTCGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRKSVILASTLAGAALAASLWYIRQDESLAASAVVRVPSAAVPVITARVARSDVPVYLRGIGTVVAYNTDVVRSQIQGQL
TAIDFTEGQFVKAGDMLAQIDPRPYQAQIAQLTANRDRDVAHLANAKANLDRDTQLGDKGFASTQAIETQQAKVSQLQAA
VEADQAAIDQANVQLGYTRLTSPIPGITGVRQIDIGNIIHTTDPNGLVVVTQIEPISVLFALPEADLPRIQTQMAKGSLP
VIAYTQDGRTRLDEGKLLLVNNQIDQATGTVQLKAEFANTEHRLWPGQLITVNLLLTTRKNAVTVAGSAVQQGPNGSYIF
VVSPSGTAEMRPVTVGQISRGQALIDSGLAGDETVVVDGQYRLQQGSRVEPLHGKAAQEADLQSAVQDALP

Sequences:

>Translated_391_residues
MRKSVILASTLAGAALAASLWYIRQDESLAASAVVRVPSAAVPVITARVARSDVPVYLRGIGTVVAYNTDVVRSQIQGQL
TAIDFTEGQFVKAGDMLAQIDPRPYQAQIAQLTANRDRDVAHLANAKANLDRDTQLGDKGFASTQAIETQQAKVSQLQAA
VEADQAAIDQANVQLGYTRLTSPIPGITGVRQIDIGNIIHTTDPNGLVVVTQIEPISVLFALPEADLPRIQTQMAKGSLP
VIAYTQDGRTRLDEGKLLLVNNQIDQATGTVQLKAEFANTEHRLWPGQLITVNLLLTTRKNAVTVAGSAVQQGPNGSYIF
VVSPSGTAEMRPVTVGQISRGQALIDSGLAGDETVVVDGQYRLQQGSRVEPLHGKAAQEADLQSAVQDALP
>Mature_391_residues
MRKSVILASTLAGAALAASLWYIRQDESLAASAVVRVPSAAVPVITARVARSDVPVYLRGIGTVVAYNTDVVRSQIQGQL
TAIDFTEGQFVKAGDMLAQIDPRPYQAQIAQLTANRDRDVAHLANAKANLDRDTQLGDKGFASTQAIETQQAKVSQLQAA
VEADQAAIDQANVQLGYTRLTSPIPGITGVRQIDIGNIIHTTDPNGLVVVTQIEPISVLFALPEADLPRIQTQMAKGSLP
VIAYTQDGRTRLDEGKLLLVNNQIDQATGTVQLKAEFANTEHRLWPGQLITVNLLLTTRKNAVTVAGSAVQQGPNGSYIF
VVSPSGTAEMRPVTVGQISRGQALIDSGLAGDETVVVDGQYRLQQGSRVEPLHGKAAQEADLQSAVQDALP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=336, Percent_Identity=39.2857142857143, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789929, Length=373, Percent_Identity=26.0053619302949, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786668, Length=363, Percent_Identity=29.2011019283747, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789665, Length=317, Percent_Identity=28.7066246056782, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081951, Length=163, Percent_Identity=28.8343558282209, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41593; Mature: 41593

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVILASTLAGAALAASLWYIRQDESLAASAVVRVPSAAVPVITARVARSDVPVYLRG
CCCCEEEEHHHHHHHHHHHEEEEECCCCHHHHHEEECCCCCCCHHHHHHHCCCCCEEEEE
IGTVVAYNTDVVRSQIQGQLTAIDFTEGQFVKAGDMLAQIDPRPYQAQIAQLTANRDRDV
CCEEEEECHHHHHHHHCCEEEEEEECCCCEEECCCEEEECCCCCHHHHHHHHHCCCCCCH
AHLANAKANLDRDTQLGDKGFASTQAIETQQAKVSQLQAAVEADQAAIDQANVQLGYTRL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TSPIPGITGVRQIDIGNIIHTTDPNGLVVVTQIEPISVLFALPEADLPRIQTQMAKGSLP
CCCCCCCCCEEEEECCCEEEECCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHCCCCC
VIAYTQDGRTRLDEGKLLLVNNQIDQATGTVQLKAEFANTEHRLWPGQLITVNLLLTTRK
EEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCEECCCCEEEEEEEEEECC
NAVTVAGSAVQQGPNGSYIFVVSPSGTAEMRPVTVGQISRGQALIDSGLAGDETVVVDGQ
CEEEEECHHHHCCCCCCEEEEECCCCCCEECCEEECCCCCCCHHHHCCCCCCCEEEECCC
YRLQQGSRVEPLHGKAAQEADLQSAVQDALP
CEECCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKSVILASTLAGAALAASLWYIRQDESLAASAVVRVPSAAVPVITARVARSDVPVYLRG
CCCCEEEEHHHHHHHHHHHEEEEECCCCHHHHHEEECCCCCCCHHHHHHHCCCCCEEEEE
IGTVVAYNTDVVRSQIQGQLTAIDFTEGQFVKAGDMLAQIDPRPYQAQIAQLTANRDRDV
CCEEEEECHHHHHHHHCCEEEEEEECCCCEEECCCEEEECCCCCHHHHHHHHHCCCCCCH
AHLANAKANLDRDTQLGDKGFASTQAIETQQAKVSQLQAAVEADQAAIDQANVQLGYTRL
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TSPIPGITGVRQIDIGNIIHTTDPNGLVVVTQIEPISVLFALPEADLPRIQTQMAKGSLP
CCCCCCCCCEEEEECCCEEEECCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHCCCCC
VIAYTQDGRTRLDEGKLLLVNNQIDQATGTVQLKAEFANTEHRLWPGQLITVNLLLTTRK
EEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCEECCCCEEEEEEEEEECC
NAVTVAGSAVQQGPNGSYIFVVSPSGTAEMRPVTVGQISRGQALIDSGLAGDETVVVDGQ
CEEEEECHHHHCCCCCCEEEEECCCCCCEECCEEECCCCCCCHHHHCCCCCCCEEEECCC
YRLQQGSRVEPLHGKAAQEADLQSAVQDALP
CEECCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]