BacMap

Definition	Rhodopseudomonas palustris TIE-1 chromosome, complete genome.
Accession	NC_011004
Length	5,744,041

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The map label for this gene is fixR [H]

Identifier: 192289798

GI number: 192289798

Start: 1461815

End: 1462591

Strand: Reverse

Name: fixR [H]

Synonym: Rpal_1388

Alternate gene names: 192289798

Gene position: 1462591-1461815 (Counterclockwise)

Preceding gene: 192289799

Following gene: 192289793

Centisome position: 25.46

GC content: 67.44

Gene sequence:

>777_bases
ATGAGCCCCGACTCCCAAAAGCCGCGCCCGCCCGAGAGCAACGCGCCGCGCCGGACCATGATCCTGACCGGCGCCAGCCG
CGGCATCGGCCACGCCACGGTGATCCGCTTCTCTAGCGCCGGCTGGCGAGTGATCACTTGCTCGCGCCATCCGTTTCCGG
AGCAGTGCCCCTGGGGGGCCGGGCCGGAAGACCACATTCAGGTCGACCTCGGCGACCGTGCCGACACGCTGCGGGCGATC
GACGAGATCCGCGAGCGGCTCGACGGCGGTGTGCTGCATGCACTGGTCAATAACGCCGCGATCTCCCCAAAGGCGGCGGG
CGGCGCCCGTCTCGGCACCATCGACACCGAAATCGATACCTGGGAGCACGTGTTCCGGGTGAATTTCTTCGCCCCGATCC
TGATGGCGCGCGGGCTGATCGAGGAACTGAAGGCGGTCAAGGGGTCGGTGGTGAACGTCACCTCGATCGCCGGTTCGCGG
GTGCACCCGTTCGCCGGCGCCGCCTACGCCACCTCGAAGGCAGCGCTCGCGGCGCTGACCCGGGAGATGGCGGCGGATTT
CGGCCATGTCGGCGTCCGGGTCAACTCGATCGCGCCGGGCGAGATCGATACGTCGATCCTGTCGCCGGGCACCGAAAAGA
TCGTCGAGGAGCAGATCCCGATGCGCCGCCTCGGCACCCCGGACGAGGTTGCCAAGATCATCTACGTGCTGTGCACCGAG
ACGTCGTCTTATGTGAACGGCGCCGAAATCCACATCAACGGCGGCCAGCACGTTTGA

Upstream 100 bases:

>100_bases
GGATCGAGTTTTGGCACGACCGTCCGTTCCGCCTGCACGACCGCATCGAATTTCGCCGGGACACCCCGGATCACCCCTGG
ACCAAGACAAGGCTGTATCC

Downstream 100 bases:

>100_bases
TTCTGCGCCCGGCCACCTAAGCCGGGCCTGCAGCAGCTACCAAGCTGAAATGCCCCCGAAAAGACCAACGCCCCATTTCC
GATCGCATCGGAAACGGGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSPDSQKPRPPESNAPRRTMILTGASRGIGHATVIRFSSAGWRVITCSRHPFPEQCPWGAGPEDHIQVDLGDRADTLRAI
DEIRERLDGGVLHALVNNAAISPKAAGGARLGTIDTEIDTWEHVFRVNFFAPILMARGLIEELKAVKGSVVNVTSIAGSR
VHPFAGAAYATSKAALAALTREMAADFGHVGVRVNSIAPGEIDTSILSPGTEKIVEEQIPMRRLGTPDEVAKIIYVLCTE
TSSYVNGAEIHINGGQHV

Sequences:

>Translated_258_residues
MSPDSQKPRPPESNAPRRTMILTGASRGIGHATVIRFSSAGWRVITCSRHPFPEQCPWGAGPEDHIQVDLGDRADTLRAI
DEIRERLDGGVLHALVNNAAISPKAAGGARLGTIDTEIDTWEHVFRVNFFAPILMARGLIEELKAVKGSVVNVTSIAGSR
VHPFAGAAYATSKAALAALTREMAADFGHVGVRVNSIAPGEIDTSILSPGTEKIVEEQIPMRRLGTPDEVAKIIYVLCTE
TSSYVNGAEIHINGGQHV
>Mature_257_residues
SPDSQKPRPPESNAPRRTMILTGASRGIGHATVIRFSSAGWRVITCSRHPFPEQCPWGAGPEDHIQVDLGDRADTLRAID
EIRERLDGGVLHALVNNAAISPKAAGGARLGTIDTEIDTWEHVFRVNFFAPILMARGLIEELKAVKGSVVNVTSIAGSRV
HPFAGAAYATSKAALAALTREMAADFGHVGVRVNSIAPGEIDTSILSPGTEKIVEEQIPMRRLGTPDEVAKIIYVLCTET
SSYVNGAEIHINGGQHV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=30.3370786516854, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=29.4354838709677, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.1587301587302, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.4354838709677, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=161, Percent_Identity=31.055900621118, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=25.9574468085106, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI126723750, Length=173, Percent_Identity=30.0578034682081, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503301, Length=123, Percent_Identity=38.2113821138211, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=24.5762711864407, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI119392083, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=30.4568527918782, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=24.7011952191235, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=31.4285714285714, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=31.1284046692607, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.718875502008, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=29.0076335877863, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=27.1653543307087, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=26.4367816091954, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=32.4528301886792, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=33.5849056603774, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=31.9066147859922, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=27.9835390946502, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=31.6793893129771, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=31.5175097276265, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=31.6793893129771, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=30.9160305343511, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=29.6153846153846, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=29.1828793774319, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=30.3846153846154, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=28.2945736434109, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=29.8449612403101, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=29.6153846153846, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=25.5474452554745, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=27.2373540856031, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=25.7936507936508, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=29.1866028708134, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=29.3233082706767, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=26.5384615384615, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=142, Percent_Identity=29.5774647887324, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=206, Percent_Identity=28.6407766990291, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=33.4630350194552, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.8387096774194, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.5220883534137, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=30.3846153846154, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=36.4130434782609, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=34.8, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=29.296875, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=27.8625954198473, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27614; Mature: 27482

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDSQKPRPPESNAPRRTMILTGASRGIGHATVIRFSSAGWRVITCSRHPFPEQCPWGA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
GPEDHIQVDLGDRADTLRAIDEIRERLDGGVLHALVNNAAISPKAAGGARLGTIDTEIDT
CCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEECEECCCHHH
WEHVFRVNFFAPILMARGLIEELKAVKGSVVNVTSIAGSRVHPFAGAAYATSKAALAALT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
REMAADFGHVGVRVNSIAPGEIDTSILSPGTEKIVEEQIPMRRLGTPDEVAKIIYVLCTE
HHHHHCCCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHEECC
TSSYVNGAEIHINGGQHV
CCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SPDSQKPRPPESNAPRRTMILTGASRGIGHATVIRFSSAGWRVITCSRHPFPEQCPWGA
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
GPEDHIQVDLGDRADTLRAIDEIRERLDGGVLHALVNNAAISPKAAGGARLGTIDTEIDT
CCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEECEECCCHHH
WEHVFRVNFFAPILMARGLIEELKAVKGSVVNVTSIAGSRVHPFAGAAYATSKAALAALT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
REMAADFGHVGVRVNSIAPGEIDTSILSPGTEKIVEEQIPMRRLGTPDEVAKIIYVLCTE
HHHHHCCCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHEECC
TSSYVNGAEIHINGGQHV
CCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3313281; 11157954; 12597275 [H]