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The map label for this gene is pgsA [H]

Identifier: 192289771

GI number: 192289771

Start: 1433125

End: 1433751

Strand: Reverse

Name: pgsA [H]

Synonym: Rpal_1361

Alternate gene names: 192289771

Gene position: 1433751-1433125 (Counterclockwise)

Preceding gene: 192289772

Following gene: 192289770

Centisome position: 24.96

GC content: 64.59

Gene sequence:

>627_bases
ATGAACAACGTCTCGACGAGAGCGCCGGTGCGGGGAACGAAGACGTCACTGACGCTTCCGAACATCCTCACCTATGCCCG
CATCGCGGCGATCCCGGTGGTGGTCGGCTGCATCTTCGCTCAGTCCATCCTCGGTGGACCGCTGGCGCTGCGCTGGGTGG
CCCTGGCGGTGTTCATCGCCGCGGCGATCACCGATTTCCTCGACGGCCATTTCGCCCGGATCTGGGATCAGCAGTCGGCA
TTCGGCCGGATGCTCGATCCGATCGCCGACAAGCTGCTGGTAGCATCCTGCCTGCTGATGCTGGCGGCCGACAGCATCAT
TCATGGCTGGACGCTGTGGGCAGCGATCGTGATCCTGTGCCGCGAGATCCTGGTGTCGGGCCTGCGCGAATATCTCGCCG
CGCTGCGCGTCAGCGTGCCGGTGACGCGGCTCGCGAAATGGAAGACCACCGCGCAGCTGGTCGCGATCGGCTTCCTGCTC
GCAGGTGAAGCCGGCGACGAGGTGCTGCCCTTCACCACCGAGATCGGCGTATCGCTGCTGTGGCTGTCGGCGCTGCTGAC
GATGTACACCGGCTACGACTATTTCCGCGCCGGCATTCACCACCTGATCGAAGAGGATCAGGCATGA

Upstream 100 bases:

>100_bases
GCGGCCGCGCCCAATGCGGATTTCACCTTTTCCTGATACGGAACGAGAGCACCCGGGTCGGAGGTTGACCTTCCGTCGCG
GGCAGTATTGGTAAGTCACG

Downstream 100 bases:

>100_bases
AGGTGAAGTATTTCGCCTGGGTGCGCGAGCGGATCGGCGTCGACGAAGAGACGGTCGAACCGCCGCCGGCGGTGACAACC
GTCGCCGACCTGATTGGCTG

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNNVSTRAPVRGTKTSLTLPNILTYARIAAIPVVVGCIFAQSILGGPLALRWVALAVFIAAAITDFLDGHFARIWDQQSA
FGRMLDPIADKLLVASCLLMLAADSIIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTRLAKWKTTAQLVAIGFLL
AGEAGDEVLPFTTEIGVSLLWLSALLTMYTGYDYFRAGIHHLIEEDQA

Sequences:

>Translated_208_residues
MNNVSTRAPVRGTKTSLTLPNILTYARIAAIPVVVGCIFAQSILGGPLALRWVALAVFIAAAITDFLDGHFARIWDQQSA
FGRMLDPIADKLLVASCLLMLAADSIIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTRLAKWKTTAQLVAIGFLL
AGEAGDEVLPFTTEIGVSLLWLSALLTMYTGYDYFRAGIHHLIEEDQA
>Mature_208_residues
MNNVSTRAPVRGTKTSLTLPNILTYARIAAIPVVVGCIFAQSILGGPLALRWVALAVFIAAAITDFLDGHFARIWDQQSA
FGRMLDPIADKLLVASCLLMLAADSIIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTRLAKWKTTAQLVAIGFLL
AGEAGDEVLPFTTEIGVSLLWLSALLTMYTGYDYFRAGIHHLIEEDQA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=194, Percent_Identity=36.5979381443299, Blast_Score=100, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320059, Length=178, Percent_Identity=29.7752808988764, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22622; Mature: 22622

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVSTRAPVRGTKTSLTLPNILTYARIAAIPVVVGCIFAQSILGGPLALRWVALAVFIA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAITDFLDGHFARIWDQQSAFGRMLDPIADKLLVASCLLMLAADSIIHGWTLWAAIVILC
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REILVSGLREYLAALRVSVPVTRLAKWKTTAQLVAIGFLLAGEAGDEVLPFTTEIGVSLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
WLSALLTMYTGYDYFRAGIHHLIEEDQA
HHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNVSTRAPVRGTKTSLTLPNILTYARIAAIPVVVGCIFAQSILGGPLALRWVALAVFIA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAITDFLDGHFARIWDQQSAFGRMLDPIADKLLVASCLLMLAADSIIHGWTLWAAIVILC
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REILVSGLREYLAALRVSVPVTRLAKWKTTAQLVAIGFLLAGEAGDEVLPFTTEIGVSLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
WLSALLTMYTGYDYFRAGIHHLIEEDQA
HHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA