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The map label for this gene is moaE [H]

Identifier: 192289769

GI number: 192289769

Start: 1432383

End: 1432850

Strand: Reverse

Name: moaE [H]

Synonym: Rpal_1359

Alternate gene names: 192289769

Gene position: 1432850-1432383 (Counterclockwise)

Preceding gene: 192289770

Following gene: 192289768

Centisome position: 24.94

GC content: 66.88

Gene sequence:

>468_bases
ATGACCGTTCCGGTGACCATCCGCATTCAGGAAGCCGATTTCGACGTCGCCGCCGAGACCGCCGCGATGACGCGCGGTCG
TAACGATATCGGCGCGGTGGTGTCGTTCATGGGCCTGTGCCGCGGCGTCGAAGGTGACGACACTGTCGCGGCGCTGACGC
TCGAGCACTATCCCGGCATGGCCGAGGAGGAAATCCAGCGCCATGCCGATGAGGCGATCAAGCGCTGGCCGATCACCGCG
CTGACGATCATCCACCGCGTCGGCCGTCTGGTGCCGGGCGACAACATCGTACTGGTGCTGGCGGCCTCGGCACATCGCCA
GGCGGCGTTCGCGGCGGCGGAATTCCTGATGGACTATCTTAAGGCCAACGCGCCGTTCTGGAAGCGCGAGGAGCGCTCAG
ACGGCTCGCGCTGGGTCGAGGCGCACAGCCGCGACGACGCCGCGCTGGCGCGATGGAGCAAGGATTGA

Upstream 100 bases:

>100_bases
CCCATGTCCGCGCCGAGACGCCGATTCATGGCGCACGCGAGGTCGCATTCTTCCCGCCGATGACCGGCGGTTGAGCCGGC
GCAACGCACGGGATGATCCG

Downstream 100 bases:

>100_bases
TGGCGAAGAAAACAAAAGCGAAAGCCGCCAAGGCAGCTAGGCCGAAAGCTGCGAAGACGGCTGTCGCGAAGGCGAAACCC
GCCAAGCGCGGCGTCGCCGC

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTVPVTIRIQEADFDVAAETAAMTRGRNDIGAVVSFMGLCRGVEGDDTVAALTLEHYPGMAEEEIQRHADEAIKRWPITA
LTIIHRVGRLVPGDNIVLVLAASAHRQAAFAAAEFLMDYLKANAPFWKREERSDGSRWVEAHSRDDAALARWSKD

Sequences:

>Translated_155_residues
MTVPVTIRIQEADFDVAAETAAMTRGRNDIGAVVSFMGLCRGVEGDDTVAALTLEHYPGMAEEEIQRHADEAIKRWPITA
LTIIHRVGRLVPGDNIVLVLAASAHRQAAFAAAEFLMDYLKANAPFWKREERSDGSRWVEAHSRDDAALARWSKD
>Mature_154_residues
TVPVTIRIQEADFDVAAETAAMTRGRNDIGAVVSFMGLCRGVEGDDTVAALTLEHYPGMAEEEIQRHADEAIKRWPITAL
TIIHRVGRLVPGDNIVLVLAASAHRQAAFAAAEFLMDYLKANAPFWKREERSDGSRWVEAHSRDDAALARWSKD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=108, Percent_Identity=31.4814814814815, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=50, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17145; Mature: 17013

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPVTIRIQEADFDVAAETAAMTRGRNDIGAVVSFMGLCRGVEGDDTVAALTLEHYPGM
CCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCC
AEEEIQRHADEAIKRWPITALTIIHRVGRLVPGDNIVLVLAASAHRQAAFAAAEFLMDYL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
KANAPFWKREERSDGSRWVEAHSRDDAALARWSKD
HCCCCCCCCCCCCCCHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
TVPVTIRIQEADFDVAAETAAMTRGRNDIGAVVSFMGLCRGVEGDDTVAALTLEHYPGM
CCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCC
AEEEIQRHADEAIKRWPITALTIIHRVGRLVPGDNIVLVLAASAHRQAAFAAAEFLMDYL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
KANAPFWKREERSDGSRWVEAHSRDDAALARWSKD
HCCCCCCCCCCCCCCHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]