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The map label for this gene is sugE [H]

Identifier: 192289224

GI number: 192289224

Start: 834360

End: 834683

Strand: Reverse

Name: sugE [H]

Synonym: Rpal_0796

Alternate gene names: 192289224

Gene position: 834683-834360 (Counterclockwise)

Preceding gene: 192289225

Following gene: 192289223

Centisome position: 14.53

GC content: 65.74

Gene sequence:

>324_bases
ATGACCGGCTGGCTCGCGCTGTTTGCCGCGGGCCTGATGGAGATCGTCTGGGCGCTGGGGCTGAAGCATTCCGAGGGCTT
CACCCGGTTCTGGCCCGCGGTCGTGACCCTGGCCGCTATCCTGGCCAGCTTCGGCCTGATGAGCATAGCCTTGAAATCGC
TGCCGTTCGGCACCGCCTATGCGGTGTGGACCGGAATCGGCGCTGCCGGCAGCATCGTGGTCGGAATGACGCTGTATGGC
GAGCCGGCCAGCGGGCTACGGGTGTTGTGCCTGTCGATGATCGTTGCCGGCATGATCGGGCTGAAGCTCAGCACTCCCGC
CTAG

Upstream 100 bases:

>100_bases
TGCAAGTCGCGGCCCGAACCGGCGCCGGCCTGCGGTTCGAGCGGCCGTATCGGGGCTATGCGCAGCGCGCCGTGCTGACG
CTGCCGCCGCGCAAGAAGCC

Downstream 100 bases:

>100_bases
GCAGCCCAACCAAGGCGGCGATTGACAAAGCAGGCCCGCTTCCATTTGATCGCGCCCGTTCAGGTGTGCCGGGAATCGTC
CGGCACAGGGAAGCCGGTGC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MTGWLALFAAGLMEIVWALGLKHSEGFTRFWPAVVTLAAILASFGLMSIALKSLPFGTAYAVWTGIGAAGSIVVGMTLYG
EPASGLRVLCLSMIVAGMIGLKLSTPA

Sequences:

>Translated_107_residues
MTGWLALFAAGLMEIVWALGLKHSEGFTRFWPAVVTLAAILASFGLMSIALKSLPFGTAYAVWTGIGAAGSIVVGMTLYG
EPASGLRVLCLSMIVAGMIGLKLSTPA
>Mature_106_residues
TGWLALFAAGLMEIVWALGLKHSEGFTRFWPAVVTLAAILASFGLMSIALKSLPFGTAYAVWTGIGAAGSIVVGMTLYGE
PASGLRVLCLSMIVAGMIGLKLSTPA

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=54.9019607843137, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11061; Mature: 10930

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWLALFAAGLMEIVWALGLKHSEGFTRFWPAVVTLAAILASFGLMSIALKSLPFGTAY
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVWTGIGAAGSIVVGMTLYGEPASGLRVLCLSMIVAGMIGLKLSTPA
HHHHCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGWLALFAAGLMEIVWALGLKHSEGFTRFWPAVVTLAAILASFGLMSIALKSLPFGTAY
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AVWTGIGAAGSIVVGMTLYGEPASGLRVLCLSMIVAGMIGLKLSTPA
HHHHCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]