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The map label for this gene is ffh [H]

Identifier: 192288677

GI number: 192288677

Start: 261654

End: 263204

Strand: Reverse

Name: ffh [H]

Synonym: Rpal_0246

Alternate gene names: 192288677

Gene position: 263204-261654 (Counterclockwise)

Preceding gene: 192288680

Following gene: 192288676

Centisome position: 4.58

GC content: 66.41

Gene sequence:

>1551_bases
ATGTTCGATAATCTCTCGGATAAGCTGGGCGGTATTCTCGATCGGCTGACCGGGCGCGGTGCGCTCAGCGAGGCCGATGT
CGATGCGGCGATGCGCGAAATCCGCCGCGCGCTGCTGGAAGCCGACGTCGCCCTCGAAGTGGTGCGCTCGTTCACCGAGC
GGGTCCGCGAGCAGGCCGTCGGCGCCACCGTCGTCAAGTCGGTCAAGCCCGGCCAGATGGTGGTCAAGATCGTCAATGAC
GAGCTGATCGCCACGCTGGGGTCGGAAGTCCAGTCGATCGACCTCAACGCCGTGCCGCCGGTGCCGATCATGATGGTCGG
TCTGCAGGGCTCGGGTAAGACCACCACCACCGCCAAGCTGGCGCGCCGCATGACCGAGCGCGACAAGCGCAAGGTGCTGA
TGGCCTCGCTCGACGTCTATCGTCCGGCCGCCATGGAGCAGCTCGCGGTGCTCGGCCGCGATCTGCAGATCGACACGCTG
CCGATCGTCGCCGGTCAGCAACCGCCGGATATCGCCCGGCGCGCGATGGAAGCCGGCAAGCTCGGCGGTTACGACGTCGT
GCTGCTCGACACCGCCGGCCGCACCACGCTCGACGAAGACATGATGGCCGAGGCGGCCGAAATCAAAGCCGCCGCGAACC
CGCACGAAGTGCTGCTGGTCGCCGACAGCCTGACCGGTCAGGACGCCGTCAATCTCGCCCGCGCGTTCGATCAGCGCGTC
GGCCTCACCGGCATCGTGCTGACCCGAATTGACGGCGATGGTCGCGGCGGTGCCGCGCTGTCGATGCGCGCCGTCACCGG
CAAGCCGATCAAGCTGATGGGCACCGGCGAAAAGACCGATGCGCTCGAAGACTTCCATCCGAGCCGGATCGCCAGCCGCA
TTCTCGGCATGGGCGACATCGTCTCGCTGGTCGAAAAAGCCGCCGCGACGCTGGACGCCGAAAAGGCCGCCGCCGTCGCC
GAGAAGATGCGCAAGGGCAAGTTCGATCTGACGGACTTGCGCGATCAGTTGCTGCAGATGACCAAGATGGGCGGCATCGG
CGGCCTGATGGGCCTGATGCCCGGCATCTCCAAGATGAAGAACCAGATCGCCGCCTCCGGCATCGACGACAAGGTGCTCA
AGCGCCAGGTCGCGATCATCGATTCGATGACCCGCGAGGAGCGCAAGAACCCCGACATCCTCAAGGCCAGCCGCAAGAAG
CGCATCGCCGCCGGCGCCGGCATCAAGGTCGAGGACGTCAACAAGCTGCTGAAGATGCATCGCAACATGGCCGACATGAT
GAAGGCCGTGGGTCGCGGTAAGGGCGGCCCGATGGCCGGCTTCGCCAAGGCGATGGGCTTCGGCGGTGGTCTGCCCTCGC
CCGACGAGATCAAGGCGATGCAGGAAAAGATGAAGAGCGGCGACATGCCCGAAGGCCTGCCGGAGCTGCCGAAGGACCTG
CCTGCCTCGTTGCGTGGCGGCATGCCCAATCTGCCCGGCCTCACCGGCCTGGCCGGCAAGCCGACGCTGCCCGGCCTCGG
CGGCTTCCCGGGATTCGGGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
GGCCGGAGGTCAACGTCCGACAGCGCGATGCGCCCTCGGGCGCAATAAGTGTTTGGTTTTGTAGGCCTTTCGCCGGAAGG
CCGTCGCTGGAATTGGGCCG

Downstream 100 bases:

>100_bases
GCCGCCTTGCTCTCCCTCTCGGTCATTCCGGGGCGCCGCGCAGCGGCGAACCCGGAATCTCCTCCCCACAACACCTCGGG
ATTCCGGGTTCGCGCTCCGC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MFDNLSDKLGGILDRLTGRGALSEADVDAAMREIRRALLEADVALEVVRSFTERVREQAVGATVVKSVKPGQMVVKIVND
ELIATLGSEVQSIDLNAVPPVPIMMVGLQGSGKTTTTAKLARRMTERDKRKVLMASLDVYRPAAMEQLAVLGRDLQIDTL
PIVAGQQPPDIARRAMEAGKLGGYDVVLLDTAGRTTLDEDMMAEAAEIKAAANPHEVLLVADSLTGQDAVNLARAFDQRV
GLTGIVLTRIDGDGRGGAALSMRAVTGKPIKLMGTGEKTDALEDFHPSRIASRILGMGDIVSLVEKAAATLDAEKAAAVA
EKMRKGKFDLTDLRDQLLQMTKMGGIGGLMGLMPGISKMKNQIAASGIDDKVLKRQVAIIDSMTREERKNPDILKASRKK
RIAAGAGIKVEDVNKLLKMHRNMADMMKAVGRGKGGPMAGFAKAMGFGGGLPSPDEIKAMQEKMKSGDMPEGLPELPKDL
PASLRGGMPNLPGLTGLAGKPTLPGLGGFPGFGKKK

Sequences:

>Translated_516_residues
MFDNLSDKLGGILDRLTGRGALSEADVDAAMREIRRALLEADVALEVVRSFTERVREQAVGATVVKSVKPGQMVVKIVND
ELIATLGSEVQSIDLNAVPPVPIMMVGLQGSGKTTTTAKLARRMTERDKRKVLMASLDVYRPAAMEQLAVLGRDLQIDTL
PIVAGQQPPDIARRAMEAGKLGGYDVVLLDTAGRTTLDEDMMAEAAEIKAAANPHEVLLVADSLTGQDAVNLARAFDQRV
GLTGIVLTRIDGDGRGGAALSMRAVTGKPIKLMGTGEKTDALEDFHPSRIASRILGMGDIVSLVEKAAATLDAEKAAAVA
EKMRKGKFDLTDLRDQLLQMTKMGGIGGLMGLMPGISKMKNQIAASGIDDKVLKRQVAIIDSMTREERKNPDILKASRKK
RIAAGAGIKVEDVNKLLKMHRNMADMMKAVGRGKGGPMAGFAKAMGFGGGLPSPDEIKAMQEKMKSGDMPEGLPELPKDL
PASLRGGMPNLPGLTGLAGKPTLPGLGGFPGFGKKK
>Mature_516_residues
MFDNLSDKLGGILDRLTGRGALSEADVDAAMREIRRALLEADVALEVVRSFTERVREQAVGATVVKSVKPGQMVVKIVND
ELIATLGSEVQSIDLNAVPPVPIMMVGLQGSGKTTTTAKLARRMTERDKRKVLMASLDVYRPAAMEQLAVLGRDLQIDTL
PIVAGQQPPDIARRAMEAGKLGGYDVVLLDTAGRTTLDEDMMAEAAEIKAAANPHEVLLVADSLTGQDAVNLARAFDQRV
GLTGIVLTRIDGDGRGGAALSMRAVTGKPIKLMGTGEKTDALEDFHPSRIASRILGMGDIVSLVEKAAATLDAEKAAAVA
EKMRKGKFDLTDLRDQLLQMTKMGGIGGLMGLMPGISKMKNQIAASGIDDKVLKRQVAIIDSMTREERKNPDILKASRKK
RIAAGAGIKVEDVNKLLKMHRNMADMMKAVGRGKGGPMAGFAKAMGFGGGLPSPDEIKAMQEKMKSGDMPEGLPELPKDL
PASLRGGMPNLPGLTGLAGKPTLPGLGGFPGFGKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=440, Percent_Identity=30.4545454545455, Blast_Score=202, Evalue=9e-52,
Organism=Homo sapiens, GI226371618, Length=341, Percent_Identity=32.8445747800587, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI23308697, Length=299, Percent_Identity=28.4280936454849, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI295424842, Length=299, Percent_Identity=28.4280936454849, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=53.7735849056604, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1789874, Length=258, Percent_Identity=35.2713178294574, Blast_Score=131, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=450, Percent_Identity=28.8888888888889, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=306, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=487, Percent_Identity=31.006160164271, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6320498, Length=315, Percent_Identity=25.3968253968254, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17647949, Length=455, Percent_Identity=30.3296703296703, Blast_Score=185, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24641198, Length=305, Percent_Identity=30.4918032786885, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 54699; Mature: 54699

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDNLSDKLGGILDRLTGRGALSEADVDAAMREIRRALLEADVALEVVRSFTERVREQAV
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATVVKSVKPGQMVVKIVNDELIATLGSEVQSIDLNAVPPVPIMMVGLQGSGKTTTTAKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHH
ARRMTERDKRKVLMASLDVYRPAAMEQLAVLGRDLQIDTLPIVAGQQPPDIARRAMEAGK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCC
LGGYDVVLLDTAGRTTLDEDMMAEAAEIKAAANPHEVLLVADSLTGQDAVNLARAFDQRV
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GLTGIVLTRIDGDGRGGAALSMRAVTGKPIKLMGTGEKTDALEDFHPSRIASRILGMGDI
CCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHCCHHHHHHHHHCHHHH
VSLVEKAAATLDAEKAAAVAEKMRKGKFDLTDLRDQLLQMTKMGGIGGLMGLMPGISKMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHH
NQIAASGIDDKVLKRQVAIIDSMTREERKNPDILKASRKKRIAAGAGIKVEDVNKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RNMADMMKAVGRGKGGPMAGFAKAMGFGGGLPSPDEIKAMQEKMKSGDMPEGLPELPKDL
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHC
PASLRGGMPNLPGLTGLAGKPTLPGLGGFPGFGKKK
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDNLSDKLGGILDRLTGRGALSEADVDAAMREIRRALLEADVALEVVRSFTERVREQAV
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GATVVKSVKPGQMVVKIVNDELIATLGSEVQSIDLNAVPPVPIMMVGLQGSGKTTTTAKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHH
ARRMTERDKRKVLMASLDVYRPAAMEQLAVLGRDLQIDTLPIVAGQQPPDIARRAMEAGK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCC
LGGYDVVLLDTAGRTTLDEDMMAEAAEIKAAANPHEVLLVADSLTGQDAVNLARAFDQRV
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GLTGIVLTRIDGDGRGGAALSMRAVTGKPIKLMGTGEKTDALEDFHPSRIASRILGMGDI
CCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHCCHHHHHHHHHCHHHH
VSLVEKAAATLDAEKAAAVAEKMRKGKFDLTDLRDQLLQMTKMGGIGGLMGLMPGISKMK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHH
NQIAASGIDDKVLKRQVAIIDSMTREERKNPDILKASRKKRIAAGAGIKVEDVNKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RNMADMMKAVGRGKGGPMAGFAKAMGFGGGLPSPDEIKAMQEKMKSGDMPEGLPELPKDL
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHC
PASLRGGMPNLPGLTGLAGKPTLPGLGGFPGFGKKK
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]