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The map label for this gene is yciC [H]

Identifier: 192288540

GI number: 192288540

Start: 116974

End: 117930

Strand: Reverse

Name: yciC [H]

Synonym: Rpal_0107

Alternate gene names: 192288540

Gene position: 117930-116974 (Counterclockwise)

Preceding gene: 192288541

Following gene: 192288539

Centisome position: 2.05

GC content: 65.62

Gene sequence:

>957_bases
ATGACGGCAGCATCCGCGACCATTTCAGTCACGGTAATCGGCGGCTTTCTCGGCGCGGGCAAAACCACCTTCGTCAATCA
CCTGCTGCGCAGCGGCGGCCCTCGGACGGCGGTGCTGGTCAACGATTTCGGCGAGGTCAATGTCGACGCGACACTGATCC
AGAGTCACGACGGCACCACGATGACGCTGACCAATGGCTGCATCTGCTGCAGCATCGGCACCAGCTTCATCGACACGATG
TGCCAGGTGCTCGACGCTGCGGTGCCGTTTGAGCGGATCGTGATCGAAGCCTCCGGGGTCGGCGATCCGTGGAAGATCGC
GGAAATTGCGCTGATCGAACCGTCGCTGCGGCTCGACCGGGTGATCGTGTTGGCCGATGCCAGCCGGATCGCGCAACTGA
TCGAGGATTCCAAGGTCGGCGACACCGTGCGCGGCCAGTTTGAGCGCTGTGACATTGTCCTGCTGAACAAGACCGATCTG
GTGAATGCCGAGGCTCTGACTGCTGCGCGCACCGCGGTACGAAGTCTGCGCCTGGACGTGGGTATCGTCGCAACCGCGCA
AGGCGCGATGCCGACGCTGGCAGAGCTAAAGACGGCTGCGTCGTCGAGCGGTTTCCGAGCCGACGCAGTTGATGCCGCGG
CGATCGATCACGGCGCGACCTTCAAGAGCTGGGCGTATCGCCGCGCCGGCCGGTTCGATCGCGTCCGGCTCGCCTGTGCG
GTCGATAAGCTGCCGCCGCAGCTATTGCGGCTGAAGGGGTCCTGTCGCCTCGCCGGCGAAGACGACGTCAAAGTGTTTCA
GATGGTCGAGAGCGTCTGGAGCCTGTCGCCGGCCGATGCCGGGCCGGTCGAGCCCGGCATCGTGCTGGTCGGCGTCGGCA
CCGCCGATCTGCCGCCGCCGGCCGAACTCGACGCGATCCTCGACCGCGCTTTGGCGCCGGCCGGAGCGCTGTCGTGA

Upstream 100 bases:

>100_bases
TGCTCGATGAGGATCCGCTGGCCGTTCCGCCGGAGCGGCTCAAGGAGATCGCGGTCTGGGGCACCGTGGTCGGCGGCATG
ATCAAGGAGGCGCCCCGCGC

Downstream 100 bases:

>100_bases
GGCCCACCCTGCCAGTTTCTCGCCGCGAAAGCCATGCGGCTTTCCACGTCCTGCCTCGCCCATCCTTTCTTGCAGCGGAG
TTCTGACCGATGATGTTGAC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTAASATISVTVIGGFLGAGKTTFVNHLLRSGGPRTAVLVNDFGEVNVDATLIQSHDGTTMTLTNGCICCSIGTSFIDTM
CQVLDAAVPFERIVIEASGVGDPWKIAEIALIEPSLRLDRVIVLADASRIAQLIEDSKVGDTVRGQFERCDIVLLNKTDL
VNAEALTAARTAVRSLRLDVGIVATAQGAMPTLAELKTAASSSGFRADAVDAAAIDHGATFKSWAYRRAGRFDRVRLACA
VDKLPPQLLRLKGSCRLAGEDDVKVFQMVESVWSLSPADAGPVEPGIVLVGVGTADLPPPAELDAILDRALAPAGALS

Sequences:

>Translated_318_residues
MTAASATISVTVIGGFLGAGKTTFVNHLLRSGGPRTAVLVNDFGEVNVDATLIQSHDGTTMTLTNGCICCSIGTSFIDTM
CQVLDAAVPFERIVIEASGVGDPWKIAEIALIEPSLRLDRVIVLADASRIAQLIEDSKVGDTVRGQFERCDIVLLNKTDL
VNAEALTAARTAVRSLRLDVGIVATAQGAMPTLAELKTAASSSGFRADAVDAAAIDHGATFKSWAYRRAGRFDRVRLACA
VDKLPPQLLRLKGSCRLAGEDDVKVFQMVESVWSLSPADAGPVEPGIVLVGVGTADLPPPAELDAILDRALAPAGALS
>Mature_317_residues
TAASATISVTVIGGFLGAGKTTFVNHLLRSGGPRTAVLVNDFGEVNVDATLIQSHDGTTMTLTNGCICCSIGTSFIDTMC
QVLDAAVPFERIVIEASGVGDPWKIAEIALIEPSLRLDRVIVLADASRIAQLIEDSKVGDTVRGQFERCDIVLLNKTDLV
NAEALTAARTAVRSLRLDVGIVATAQGAMPTLAELKTAASSSGFRADAVDAAAIDHGATFKSWAYRRAGRFDRVRLACAV
DKLPPQLLRLKGSCRLAGEDDVKVFQMVESVWSLSPADAGPVEPGIVLVGVGTADLPPPAELDAILDRALAPAGALS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI223941779, Length=186, Percent_Identity=33.8709677419355, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI126722884, Length=186, Percent_Identity=33.8709677419355, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI33469141, Length=186, Percent_Identity=32.258064516129, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI148727351, Length=186, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI146231952, Length=186, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI223941776, Length=173, Percent_Identity=32.3699421965318, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI119120938, Length=146, Percent_Identity=30.8219178082192, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082430, Length=290, Percent_Identity=31.3793103448276, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788499, Length=207, Percent_Identity=30.4347826086957, Blast_Score=85, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 33266; Mature: 33134

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAASATISVTVIGGFLGAGKTTFVNHLLRSGGPRTAVLVNDFGEVNVDATLIQSHDGTT
CCCCCEEEEEEEEEEHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCE
MTLTNGCICCSIGTSFIDTMCQVLDAAVPFERIVIEASGVGDPWKIAEIALIEPSLRLDR
EEEECCEEEEECCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCEEEEEEEECCCCCCCE
VIVLADASRIAQLIEDSKVGDTVRGQFERCDIVLLNKTDLVNAEALTAARTAVRSLRLDV
EEEEECHHHHHHHHHCCCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCE
GIVATAQGAMPTLAELKTAASSSGFRADAVDAAAIDHGATFKSWAYRRAGRFDRVRLACA
EEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCHHEEEEEE
VDKLPPQLLRLKGSCRLAGEDDVKVFQMVESVWSLSPADAGPVEPGIVLVGVGTADLPPP
HHHCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
AELDAILDRALAPAGALS
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAASATISVTVIGGFLGAGKTTFVNHLLRSGGPRTAVLVNDFGEVNVDATLIQSHDGTT
CCCCEEEEEEEEEEHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCE
MTLTNGCICCSIGTSFIDTMCQVLDAAVPFERIVIEASGVGDPWKIAEIALIEPSLRLDR
EEEECCEEEEECCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCEEEEEEEECCCCCCCE
VIVLADASRIAQLIEDSKVGDTVRGQFERCDIVLLNKTDLVNAEALTAARTAVRSLRLDV
EEEEECHHHHHHHHHCCCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCE
GIVATAQGAMPTLAELKTAASSSGFRADAVDAAAIDHGATFKSWAYRRAGRFDRVRLACA
EEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCCHHEEEEEE
VDKLPPQLLRLKGSCRLAGEDDVKVFQMVESVWSLSPADAGPVEPGIVLVGVGTADLPPP
HHHCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
AELDAILDRALAPAGALS
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]