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The map label for this gene is fixN [H]

Identifier: 192288453

GI number: 192288453

Start: 20369

End: 22015

Strand: Reverse

Name: fixN [H]

Synonym: Rpal_0020

Alternate gene names: 192288453

Gene position: 22015-20369 (Counterclockwise)

Preceding gene: 192288454

Following gene: 192288452

Centisome position: 0.38

GC content: 61.99

Gene sequence:

>1647_bases
ATGAATCAAGCCCTGAATTCGAAGCGGATCACCCTTGGCGAGGGTGGTCTCACGGTCGTGTTCGCATTGACCACGATCCT
GTCCATCTATGCGGCGATTTACGCCAAGGATGCTCCCTTCGCATTTCATGCCGCGCTAGCGGCCGCGTTCAGCGCATGGG
CGGTGTTCGCGATCATCGTTCGGCATCGCAGCCGTTCGGGCCTGCCGCCGCAGGAAATCAACGGCGCTCCGAATTACAAT
CTCGGGCCGATAAAGTTCCTCTCGTTCATGGCGATGTTTTGGGGCATCGCCGGCTTCTCGGCCGGCCTCTACATTGCCCT
TGAGCTTGCCTATCCGGGCTTGAACATCGCCCAGTGGGTCAACTTCGGCCGGCTCCGTCCGCTGCACACTTCGGCGGTGA
TCTTCGCATTCGGCGGCAACGTGCTGCTCGCCACCTCGTTCTACGTGGTGCAGAAGACCACCCGGGCACGGCTCGCCGGT
GACTTGGCGCCGTGGTTTGTGGCGATCGGCTACAACTTCTTCATCGTCATCGCCGGCACTGGCTATCTCCTGGGTGTCAC
CCAGTCGAAGGAATACGCCGAGCCGGAATGGTACGCCGACCTCTGGCTCACCATCGTTTGGGTTACCTACCTGCTGGTGT
TCCTGGCGACGCTGATGAAGCGCAAGGAACCCCACATCTACGTGGCGAACTGGTTCTATCTCGCGTTCATCATCACTATC
GCGGTGCTGCACCTCGGCAACAACCCGACGCTGCCGGTCAGCTTCCTCGGCTCGAAGTCCTACATCGCCTGGTCGGGCGT
GCAGGACGCGATGTTCCAGTGGTGGTACGGCCACAACGCGGTCGGCTTCTTCCTCACCGCCGGCTTCCTCGCCATCATGT
ACTACTTCATCCCGAAGCGGGCTGAACGGCCGGTCTATTCCTATCGGCTGTCGATCATCCACTTCTGGGCGCTGATCTTC
CTGTACATCTGGGCTGGTCCGCACCACCTGCACTACACCGCACTGCCCGACTGGACGCAGACCCTCGGCATGACCTTCTC
GATCATGCTGTGGATGCCCTCCTGGGGCGGCATGATCAACGGCCTGATGACGCTGTCGGGCGCCTGGGACAAGCTCCGCA
CCGACCCCGTGCTGCGCATGATGGTGGTGTCGGTCGCCTTCTACGGCATGTCGACCTTCGAAGGTCCGATGATGGCGATT
AAGGCGGTCAACTCGCTCAGCCACTACACCGACTGGACCATCGGCCACGTCCACTCCGGCGCGCTCGGCTGGGTCGGCTT
CGTCTCCTTCGGTGCTCTGTACTGCCTCGTGCCGTGGGTCTGGGGCCGCAAGCAGCTCTACAGCATCCGCCTGGTGAACT
GGCACTTCTGGATCGCGACCCTCGGCATCGTCCTCTACATCTCGGCGATGTGGGTGTCGGGCATCCTGCAAGGTCTGATG
TGGCGTGCCTACACCTCGCTCGGCTTCCTCGAATACTCGTTCATCGAGTCGGTCGAAGCGATGCACCCCTTCTATGCCAT
CCGCGCCGCCGGCGGCGGCCTGTTCCTGATCGGCGCGCTGATCATGGCATACAACCTCTGGATGACCGTTCGCGTCGGCG
AACGGTCCGAGGCTCAGCCTCGCGTCGCCCTGCAGCCTGCCGAGTAA

Upstream 100 bases:

>100_bases
CGTCGTGGCGCAAAGTTGGGCATTTTGATTTCGATCAAACGTGCGGTCCCGAAACCGGGGATGGTGCAGTCACCTGCCCG
CCGAAGAAAAGATTGATCAG

Downstream 100 bases:

>100_bases
GGAGAGCAAACAATGTCTATCTGGGCTCGGCACAAGATCTTCGAGACGAATTCGGTCGTCCTGATCGTCGGCATCCTGCT
CGTGATCGCGATCGGTGGTC

Product: cbb3-type cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome CBB3 subunit 1; Cytochrome c oxidase polypeptide I homolog; Heme B/copper cytochrome c oxidase subunit [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MNQALNSKRITLGEGGLTVVFALTTILSIYAAIYAKDAPFAFHAALAAAFSAWAVFAIIVRHRSRSGLPPQEINGAPNYN
LGPIKFLSFMAMFWGIAGFSAGLYIALELAYPGLNIAQWVNFGRLRPLHTSAVIFAFGGNVLLATSFYVVQKTTRARLAG
DLAPWFVAIGYNFFIVIAGTGYLLGVTQSKEYAEPEWYADLWLTIVWVTYLLVFLATLMKRKEPHIYVANWFYLAFIITI
AVLHLGNNPTLPVSFLGSKSYIAWSGVQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKRAERPVYSYRLSIIHFWALIF
LYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPVLRMMVVSVAFYGMSTFEGPMMAI
KAVNSLSHYTDWTIGHVHSGALGWVGFVSFGALYCLVPWVWGRKQLYSIRLVNWHFWIATLGIVLYISAMWVSGILQGLM
WRAYTSLGFLEYSFIESVEAMHPFYAIRAAGGGLFLIGALIMAYNLWMTVRVGERSEAQPRVALQPAE

Sequences:

>Translated_548_residues
MNQALNSKRITLGEGGLTVVFALTTILSIYAAIYAKDAPFAFHAALAAAFSAWAVFAIIVRHRSRSGLPPQEINGAPNYN
LGPIKFLSFMAMFWGIAGFSAGLYIALELAYPGLNIAQWVNFGRLRPLHTSAVIFAFGGNVLLATSFYVVQKTTRARLAG
DLAPWFVAIGYNFFIVIAGTGYLLGVTQSKEYAEPEWYADLWLTIVWVTYLLVFLATLMKRKEPHIYVANWFYLAFIITI
AVLHLGNNPTLPVSFLGSKSYIAWSGVQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKRAERPVYSYRLSIIHFWALIF
LYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPVLRMMVVSVAFYGMSTFEGPMMAI
KAVNSLSHYTDWTIGHVHSGALGWVGFVSFGALYCLVPWVWGRKQLYSIRLVNWHFWIATLGIVLYISAMWVSGILQGLM
WRAYTSLGFLEYSFIESVEAMHPFYAIRAAGGGLFLIGALIMAYNLWMTVRVGERSEAQPRVALQPAE
>Mature_548_residues
MNQALNSKRITLGEGGLTVVFALTTILSIYAAIYAKDAPFAFHAALAAAFSAWAVFAIIVRHRSRSGLPPQEINGAPNYN
LGPIKFLSFMAMFWGIAGFSAGLYIALELAYPGLNIAQWVNFGRLRPLHTSAVIFAFGGNVLLATSFYVVQKTTRARLAG
DLAPWFVAIGYNFFIVIAGTGYLLGVTQSKEYAEPEWYADLWLTIVWVTYLLVFLATLMKRKEPHIYVANWFYLAFIITI
AVLHLGNNPTLPVSFLGSKSYIAWSGVQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKRAERPVYSYRLSIIHFWALIF
LYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPVLRMMVVSVAFYGMSTFEGPMMAI
KAVNSLSHYTDWTIGHVHSGALGWVGFVSFGALYCLVPWVWGRKQLYSIRLVNWHFWIATLGIVLYISAMWVSGILQGLM
WRAYTSLGFLEYSFIESVEAMHPFYAIRAAGGGLFLIGALIMAYNLWMTVRVGERSEAQPRVALQPAE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61589; Mature: 61589

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQALNSKRITLGEGGLTVVFALTTILSIYAAIYAKDAPFAFHAALAAAFSAWAVFAIIV
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RHRSRSGLPPQEINGAPNYNLGPIKFLSFMAMFWGIAGFSAGLYIALELAYPGLNIAQWV
HHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
NFGRLRPLHTSAVIFAFGGNVLLATSFYVVQKTTRARLAGDLAPWFVAIGYNFFIVIAGT
CCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GYLLGVTQSKEYAEPEWYADLWLTIVWVTYLLVFLATLMKRKEPHIYVANWFYLAFIITI
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
AVLHLGNNPTLPVSFLGSKSYIAWSGVQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKR
HHHHCCCCCCEEEEECCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AERPVYSYRLSIIHFWALIFLYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMIN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEEEECCCCCHHHH
GLMTLSGAWDKLRTDPVLRMMVVSVAFYGMSTFEGPMMAIKAVNSLSHYTDWTIGHVHSG
HHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCC
ALGWVGFVSFGALYCLVPWVWGRKQLYSIRLVNWHFWIATLGIVLYISAMWVSGILQGLM
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAYTSLGFLEYSFIESVEAMHPFYAIRAAGGGLFLIGALIMAYNLWMTVRVGERSEAQP
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
RVALQPAE
CEEECCCC
>Mature Secondary Structure
MNQALNSKRITLGEGGLTVVFALTTILSIYAAIYAKDAPFAFHAALAAAFSAWAVFAIIV
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RHRSRSGLPPQEINGAPNYNLGPIKFLSFMAMFWGIAGFSAGLYIALELAYPGLNIAQWV
HHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
NFGRLRPLHTSAVIFAFGGNVLLATSFYVVQKTTRARLAGDLAPWFVAIGYNFFIVIAGT
CCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GYLLGVTQSKEYAEPEWYADLWLTIVWVTYLLVFLATLMKRKEPHIYVANWFYLAFIITI
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
AVLHLGNNPTLPVSFLGSKSYIAWSGVQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKR
HHHHCCCCCCEEEEECCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AERPVYSYRLSIIHFWALIFLYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMIN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEEEECCCCCHHHH
GLMTLSGAWDKLRTDPVLRMMVVSVAFYGMSTFEGPMMAIKAVNSLSHYTDWTIGHVHSG
HHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCC
ALGWVGFVSFGALYCLVPWVWGRKQLYSIRLVNWHFWIATLGIVLYISAMWVSGILQGLM
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRAYTSLGFLEYSFIESVEAMHPFYAIRAAGGGLFLIGALIMAYNLWMTVRVGERSEAQP
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
RVALQPAE
CEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8386371; 12597275 [H]