Click here to switch to the map view.

The map label for this gene is 192288440

Identifier: 192288440

GI number: 192288440

Start: 8982

End: 10430

Strand: Reverse

Name: 192288440

Synonym: Rpal_0007

Alternate gene names: NA

Gene position: 10430-8982 (Counterclockwise)

Preceding gene: 192288441

Following gene: 192288438

Centisome position: 0.18

GC content: 67.56

Gene sequence:

>1449_bases
ATGTCGGCGGTCTCGGCGCTGAGCAGGGCGGAACTGGAAGCCCGGCTTGAGGAGGCCGAGGAGACGCTGCGGGCGATCCG
CGACGGCGAAATCGACGCGGTCGTCGTTCGCGCCGCCGATGAAGAGCAGGTGTTCACGCTCGAAGGTGGCGGCCAGTCCT
ATCGCACCTTCATGGAAACGATGGATGTCGGTGCCGCGGCGTTCGATCAGGACGGCCAGCTGCTCTACGCCAACCAGGCG
CTGTGCGCGCTGCTCGATTGCGCCCACGGCTCGCTCACCGCTTCTGCTCTGATCGCGTTGCTCGATCCGGCCAATCAGGC
GGCGTTCCGGCGCCTTTTGGCGCAGGCCCAGCGCGAACGGCAATCGGCCGAAATCCATCTACGGGTCGGCGATGCAGAGC
GCAGCATGCTGCTCACCGGCACGCCCTTGGAGTTCGGCATCGTCCACGGCGCGGCGATCACCTTCACCGACATCAGCGAG
CGCGAGCAGGCCGCCGCCGCCCGCGAATCCGAGCGGCTGGCGCGCGCGATCCTGGCCTCGGCCAATGAAGCGGTGATCGT
GTGCGACCGCGCCGGCCGCGTCACCCATCTCAACGGCGCGGCGATGCGGATCTGCGCCGAGGCGCCGGTCGGCAAAACCT
TTGCCGAGGCGATCGCGCTGAGTTTTCCCGAAGCTTCCGAATTGATGAGCAGCGACGACATCGTCACGATGGCGACCGCG
GGCTTGCCGGTGCAGGGGCTGGAGGCGGCGGTCCGCATCCCGTCGGCCGCGATCACCGACGTGATGATCAGCGCCGCGCC
GCTGGTGGTGTCCGGCGAGCGCACCCAGGGCTGCGTCGTCACCCTGGTCGATCTGTCGCAGCGTAAGGCCGCCGAGCGGC
ACCAGGCGCTGCTGATGGGCGAGCTCGACCATCGCGTGAAGAATACGCTCACCATGGTAATGGCGATCTGCGCCCGCACC
GCCGCGCACGAGCGCACCATCGAGGATTTCCAGAAATCCTTCACCGGCCGGATTCAGGCGCTGGCGGCGACTCACACGCT
GCTGTCGAACGCCTCGTGGCAGAACCTGCATATTCGCGATGTGCTTGCCGCCGAGCTGGCGCCGTTCGCCTCGCTGTCGA
GCGGCCGCATCGTCACCGACGGTCTCGACATCGCGGTCGACGCCAAGACCGCGGTGTCGCTCGGGCTGGTGTTTCACGAA
CTCACCACCAACGCCGTGAAATACGGAGCCCTGTCAGTGCCGTCAGGGCGGATCTCGGTGCGCCGGGTCGGCGCCACCGA
CGAGGCGCTGACGATCGAATGGCAGGAGCACGACGGCCCGCCGGTGACGCCACCGCAAAGCTCCGGCTTCGGCCAGACGC
TGATCTCCCGCAGCCTCGGCAATGGCGGCGCCAAGTTGGAATTTGATCCCGCCGGCGTGGTTTGCCAGATCTCGATTCCG
AGGAGCTGA

Upstream 100 bases:

>100_bases
TGGTGAAGGAATTGCCGGTGCCGATCCGTAAGATCATCGGCGACCTGTCCGACACGCCGAAAGTCCTGGTGCATCTTGCG
GTGGAGGAGTCGTCCTCGTG

Downstream 100 bases:

>100_bases
TCGACGTCGGCCGGGCCGATGCCTTGATCGCCGCCACCCAATAGGTCAGCCGTTTGCGGGCTGCTTCAGCGGCAGCCGTG
TGCTTTCCTTGAGGCGATCC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSAVSALSRAELEARLEEAEETLRAIRDGEIDAVVVRAADEEQVFTLEGGGQSYRTFMETMDVGAAAFDQDGQLLYANQA
LCALLDCAHGSLTASALIALLDPANQAAFRRLLAQAQRERQSAEIHLRVGDAERSMLLTGTPLEFGIVHGAAITFTDISE
REQAAAARESERLARAILASANEAVIVCDRAGRVTHLNGAAMRICAEAPVGKTFAEAIALSFPEASELMSSDDIVTMATA
GLPVQGLEAAVRIPSAAITDVMISAAPLVVSGERTQGCVVTLVDLSQRKAAERHQALLMGELDHRVKNTLTMVMAICART
AAHERTIEDFQKSFTGRIQALAATHTLLSNASWQNLHIRDVLAAELAPFASLSSGRIVTDGLDIAVDAKTAVSLGLVFHE
LTTNAVKYGALSVPSGRISVRRVGATDEALTIEWQEHDGPPVTPPQSSGFGQTLISRSLGNGGAKLEFDPAGVVCQISIP
RS

Sequences:

>Translated_482_residues
MSAVSALSRAELEARLEEAEETLRAIRDGEIDAVVVRAADEEQVFTLEGGGQSYRTFMETMDVGAAAFDQDGQLLYANQA
LCALLDCAHGSLTASALIALLDPANQAAFRRLLAQAQRERQSAEIHLRVGDAERSMLLTGTPLEFGIVHGAAITFTDISE
REQAAAARESERLARAILASANEAVIVCDRAGRVTHLNGAAMRICAEAPVGKTFAEAIALSFPEASELMSSDDIVTMATA
GLPVQGLEAAVRIPSAAITDVMISAAPLVVSGERTQGCVVTLVDLSQRKAAERHQALLMGELDHRVKNTLTMVMAICART
AAHERTIEDFQKSFTGRIQALAATHTLLSNASWQNLHIRDVLAAELAPFASLSSGRIVTDGLDIAVDAKTAVSLGLVFHE
LTTNAVKYGALSVPSGRISVRRVGATDEALTIEWQEHDGPPVTPPQSSGFGQTLISRSLGNGGAKLEFDPAGVVCQISIP
RS
>Mature_481_residues
SAVSALSRAELEARLEEAEETLRAIRDGEIDAVVVRAADEEQVFTLEGGGQSYRTFMETMDVGAAAFDQDGQLLYANQAL
CALLDCAHGSLTASALIALLDPANQAAFRRLLAQAQRERQSAEIHLRVGDAERSMLLTGTPLEFGIVHGAAITFTDISER
EQAAAARESERLARAILASANEAVIVCDRAGRVTHLNGAAMRICAEAPVGKTFAEAIALSFPEASELMSSDDIVTMATAG
LPVQGLEAAVRIPSAAITDVMISAAPLVVSGERTQGCVVTLVDLSQRKAAERHQALLMGELDHRVKNTLTMVMAICARTA
AHERTIEDFQKSFTGRIQALAATHTLLSNASWQNLHIRDVLAAELAPFASLSSGRIVTDGLDIAVDAKTAVSLGLVFHEL
TTNAVKYGALSVPSGRISVRRVGATDEALTIEWQEHDGPPVTPPQSSGFGQTLISRSLGNGGAKLEFDPAGVVCQISIPR
S

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51086; Mature: 50954

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVSALSRAELEARLEEAEETLRAIRDGEIDAVVVRAADEEQVFTLEGGGQSYRTFMET
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHH
MDVGAAAFDQDGQLLYANQALCALLDCAHGSLTASALIALLDPANQAAFRRLLAQAQRER
HHCCCCEECCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
QSAEIHLRVGDAERSMLLTGTPLEFGIVHGAAITFTDISEREQAAAARESERLARAILAS
CCCEEEEEECCCCCCEEEECCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHC
ANEAVIVCDRAGRVTHLNGAAMRICAEAPVGKTFAEAIALSFPEASELMSSDDIVTMATA
CCCEEEEEECCCCEEEECCHHEEEEECCCCCHHHHHHHHHCCCCHHHHCCCCCEEEEEEC
GLPVQGLEAAVRIPSAAITDVMISAAPLVVSGERTQGCVVTLVDLSQRKAAERHQALLMG
CCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHH
ELDHRVKNTLTMVMAICARTAAHERTIEDFQKSFTGRIQALAATHTLLSNASWQNLHIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHH
VLAAELAPFASLSSGRIVTDGLDIAVDAKTAVSLGLVFHELTTNAVKYGALSVPSGRISV
HHHHHHCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEE
RRVGATDEALTIEWQEHDGPPVTPPQSSGFGQTLISRSLGNGGAKLEFDPAGVVCQISIP
EEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEEECC
RS
CC
>Mature Secondary Structure 
SAVSALSRAELEARLEEAEETLRAIRDGEIDAVVVRAADEEQVFTLEGGGQSYRTFMET
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHH
MDVGAAAFDQDGQLLYANQALCALLDCAHGSLTASALIALLDPANQAAFRRLLAQAQRER
HHCCCCEECCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
QSAEIHLRVGDAERSMLLTGTPLEFGIVHGAAITFTDISEREQAAAARESERLARAILAS
CCCEEEEEECCCCCCEEEECCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHC
ANEAVIVCDRAGRVTHLNGAAMRICAEAPVGKTFAEAIALSFPEASELMSSDDIVTMATA
CCCEEEEEECCCCEEEECCHHEEEEECCCCCHHHHHHHHHCCCCHHHHCCCCCEEEEEEC
GLPVQGLEAAVRIPSAAITDVMISAAPLVVSGERTQGCVVTLVDLSQRKAAERHQALLMG
CCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCEEEEEEECHHHHHHHHHHHHHHH
ELDHRVKNTLTMVMAICARTAAHERTIEDFQKSFTGRIQALAATHTLLSNASWQNLHIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHH
VLAAELAPFASLSSGRIVTDGLDIAVDAKTAVSLGLVFHELTTNAVKYGALSVPSGRISV
HHHHHHCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEE
RRVGATDEALTIEWQEHDGPPVTPPQSSGFGQTLISRSLGNGGAKLEFDPAGVVCQISIP
EEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEEECC
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA