Click here to switch to the map view.

The map label for this gene is nanR [H]

Identifier: 190895290

GI number: 190895290

Start: 1062558

End: 1063262

Strand: Reverse

Name: nanR [H]

Synonym: RHECIAT_PC0000963

Alternate gene names: 190895290

Gene position: 1063262-1062558 (Counterclockwise)

Preceding gene: 190895305

Following gene: 190895289

Centisome position: 97.41

GC content: 61.56

Gene sequence:

>705_bases
ATGACCCAGCCCATCGAACAAATCGTCCGCCGGAAACTCTCCGACGAAGTGTTTGATCGACTCGAGCGAATGATCACCTC
AGGCGAGCTTCAGCCCGGCGACGAAATGCCCTCCGAGCGGGTGCTGATGGAGCGCTTCGGCGTCGGCCGGCCGGCGATCC
GCGAAGCCATGCAATCGCTCGCCAACAAGGGTCTCGTCAGCATCTCGCACGGCGAGCGGGCGAAGGTCTTGCGGCTGACG
GCAAAATCGATCTTCCGCCAGGTCGATCTCACCGCCAAGATCATGCTGTCGCAATCGGCCGACTCGCTCGAACATCTGAA
GAGCGCCCGCATCTTCTTCGAGCGCGGCATGGCCCGCGAGGCCGCACAGCGCGCCTCGGCAACCGATATCAGCGACCTCA
GAGATATCATCGAGCGCCAGCGCGCCTCGCTCGGCCGGGCCGAAGAATTCATCGACGCCGATATGGAATTCCACACCCGC
ATCGCCCAGATCTCCGGAAACCCGATCTATGTCGCCGTCAGCGAGGCGATGCTCGCCTGGCTGAAGGAATATCATACCGA
GATGCTGATCTGGACCGGCAAGGAAAAGTTCACCCTCGCAGAACACGACGAAATCGTCGACCGCCTCGAAGCCAACGATG
TCGACGGCTCGGAAACGGCGCTCCTCAAGCATCTCGAGCGCTCACGCGCGCTCTATGCGAAGTAA

Upstream 100 bases:

>100_bases
ATGAAAAGCGGAATCTTCGGCGGCGCAAATTTTCAGCCGCGAGCTTTGTTCTCGGCGCGGAAAACTGTTAGGAGGAAGCA
TTTTGAGCCAGCGAGATCTC

Downstream 100 bases:

>100_bases
TCGAAGCTTTCGAAGATCGCGAAACCGAGTGGGCTATAGTCGGCGCTAAGCACGATCGACGGCATAATGATGTGGGTGCA
TCAGATGAGATTCGCTCTCA

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTQPIEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLANKGLVSISHGERAKVLRLT
AKSIFRQVDLTAKIMLSQSADSLEHLKSARIFFERGMAREAAQRASATDISDLRDIIERQRASLGRAEEFIDADMEFHTR
IAQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALLKHLERSRALYAK

Sequences:

>Translated_234_residues
MTQPIEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLANKGLVSISHGERAKVLRLT
AKSIFRQVDLTAKIMLSQSADSLEHLKSARIFFERGMAREAAQRASATDISDLRDIIERQRASLGRAEEFIDADMEFHTR
IAQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALLKHLERSRALYAK
>Mature_233_residues
TQPIEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLANKGLVSISHGERAKVLRLTA
KSIFRQVDLTAKIMLSQSADSLEHLKSARIFFERGMAREAAQRASATDISDLRDIIERQRASLGRAEEFIDADMEFHTRI
AQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALLKHLERSRALYAK

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=227, Percent_Identity=37.4449339207048, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI48994961, Length=211, Percent_Identity=27.9620853080569, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994955, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789353, Length=168, Percent_Identity=29.7619047619048, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26615; Mature: 26484

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPIEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
ANKGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSADSLEHLKSARIFFERGMARE
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AAQRASATDISDLRDIIERQRASLGRAEEFIDADMEFHTRIAQISGNPIYVAVSEAMLAW
HHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHH
LKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALLKHLERSRALYAK
HHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQPIEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
ANKGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSADSLEHLKSARIFFERGMARE
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AAQRASATDISDLRDIIERQRASLGRAEEFIDADMEFHTRIAQISGNPIYVAVSEAMLAW
HHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHH
LKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALLKHLERSRALYAK
HHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA