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The map label for this gene is lktD [H]

Identifier: 190895163

GI number: 190895163

Start: 910938

End: 912383

Strand: Reverse

Name: lktD [H]

Synonym: RHECIAT_PC0000835

Alternate gene names: 190895163

Gene position: 912383-910938 (Counterclockwise)

Preceding gene: 190895164

Following gene: 190895162

Centisome position: 83.59

GC content: 60.44

Gene sequence:

>1446_bases
ATGACTGTCGCAGCCCGAACCATCGCCGCCCCGCCTCCGCCGACGCGGTCGAGATCCGACAACCAATTCCTGGCGCCTGC
ACTCGAGGTGCTTGAAACACCGCCGTCGCCAGTCGGAACGGCGCTCCTCTTGATCATCTGCCTGCTGGCAACAATCGCCC
TGACATGGGCTTATGTCGGCAGGATCGACATCATCGCGACTGCGCAGGGCAAGATTCAACCGGTCGGCCGGGTCAAGGTC
GTCCAGCCGCTCTATGGCGGCAAGGTCGTGGTTCTGCCGCCTCCCGATGGAACCGAAGTTCATCGCGGTGAGGTGTTGTT
CCAGCTGGACCCAACCGAAGCCATCGCTGATGAAAAGGATGCGGAGGCGGCACTCTCGTCAGTCCAGGCGGAAGCTATGC
GACGGCGTGCTGCCCTGGCCGCCGCCACTGCGACGGAGGTCAACCGCAGTGCTAGAATAAACTGGGCAGCAGACGTACCC
GAGAAGCTTCGCAAGCGGGAAGACGCCATTCTCGCCAGCGAACTTGGCCAGCTTGATGCATCGCTGACGTCATTGCGTTC
CCAAGTGCGCCAGAAGGAAGGGGAGCGCGACCATCTCCAGGATACACTCGACGAGCAGGCGTCGCTCGTCGATACGCTGC
AGCAGCGGGTTGCAATGCGGAGTACTCTCGTTGGTGAGAATGCAGGGCCAGTTGCCAGCGTCATCGACGCAACCGAAACG
TTAAAGACGCAGCGAACACAATTTGCCATCCAAAAGGGTCAACTTGCCGACGCCGTGGCAGGGATCGATGTGCTCAAGGC
CGAGATCGAGAAGACCCGCAGCACGTTTATCAGCGACCAGACCGAAAGGCTCGGCGATGCCGAGCGTCAGGCCGAGGATC
TCGAAGAGCGCCTTGCAAAGACCCGCGCCGAACTCGCACAAATGACGGTGCGCAGTCCGATTGATGGCGTCGTCCAGACC
TCCGTGATTTCGACCGAGGGCCAGGTCGTGACCGCTGGCGAAGAGGTTCTGAGGGTCGTGCCGGCGGGTGCTGAGCTGGA
ACTCGAGGTTTACGTTCCCAATCGCGATATCGGCTTCATTCATGTCGGCCAGCCGGCAGTGGTCAAATTGGATGCATTTC
CGTTCACCCGATACGGTACGGTTCCGGCAACGATTACCAAGATAGCAACCGATGCCATCCCCGAGCCGGATGCTGAGCGC
CGAGAGGAAGATGCTGCTGCTGCGCCGCAGACGTCTCTGTTTGCTGGTGCCGAGCGGATCCAAAACCTTGTCTTCGCGGT
GACACTGAAACTGGAGCAAAATGCCGTGAGGGCGAATGGCGCAGATATTCCGCTTTCGCCTGGAATGTCAGCGACAGCCG
AGATGCGAACCGGTACTCGTCGGATTCTCGGGTATGTGTTTTCGCCGCTCGTCGAGGTGGCAAGCGACGCGATGAAGGAG
CGATGA

Upstream 100 bases:

>100_bases
GCCGAGTTGTCGAGATGGGAACGCACGACGAGCTTCTACAAAAGAAGGACGGTCTCTTTGCGCGGCTCTGGGCGTTACAG
CACGATACGAGGGTTCCGGC

Downstream 100 bases:

>100_bases
GTGAACGAGGAAGCTACCTAAATTTCGAGGCATCACAGGAAACAATTTGAATTCGTCGAGTTGGCACCTTCTGCCTATGA
GATAGACTGCGATGCGGACC

Product: putative HlyD family protein secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTVAARTIAAPPPPTRSRSDNQFLAPALEVLETPPSPVGTALLLIICLLATIALTWAYVGRIDIIATAQGKIQPVGRVKV
VQPLYGGKVVVLPPPDGTEVHRGEVLFQLDPTEAIADEKDAEAALSSVQAEAMRRRAALAAATATEVNRSARINWAADVP
EKLRKREDAILASELGQLDASLTSLRSQVRQKEGERDHLQDTLDEQASLVDTLQQRVAMRSTLVGENAGPVASVIDATET
LKTQRTQFAIQKGQLADAVAGIDVLKAEIEKTRSTFISDQTERLGDAERQAEDLEERLAKTRAELAQMTVRSPIDGVVQT
SVISTEGQVVTAGEEVLRVVPAGAELELEVYVPNRDIGFIHVGQPAVVKLDAFPFTRYGTVPATITKIATDAIPEPDAER
REEDAAAAPQTSLFAGAERIQNLVFAVTLKLEQNAVRANGADIPLSPGMSATAEMRTGTRRILGYVFSPLVEVASDAMKE
R

Sequences:

>Translated_481_residues
MTVAARTIAAPPPPTRSRSDNQFLAPALEVLETPPSPVGTALLLIICLLATIALTWAYVGRIDIIATAQGKIQPVGRVKV
VQPLYGGKVVVLPPPDGTEVHRGEVLFQLDPTEAIADEKDAEAALSSVQAEAMRRRAALAAATATEVNRSARINWAADVP
EKLRKREDAILASELGQLDASLTSLRSQVRQKEGERDHLQDTLDEQASLVDTLQQRVAMRSTLVGENAGPVASVIDATET
LKTQRTQFAIQKGQLADAVAGIDVLKAEIEKTRSTFISDQTERLGDAERQAEDLEERLAKTRAELAQMTVRSPIDGVVQT
SVISTEGQVVTAGEEVLRVVPAGAELELEVYVPNRDIGFIHVGQPAVVKLDAFPFTRYGTVPATITKIATDAIPEPDAER
REEDAAAAPQTSLFAGAERIQNLVFAVTLKLEQNAVRANGADIPLSPGMSATAEMRTGTRRILGYVFSPLVEVASDAMKE
R
>Mature_480_residues
TVAARTIAAPPPPTRSRSDNQFLAPALEVLETPPSPVGTALLLIICLLATIALTWAYVGRIDIIATAQGKIQPVGRVKVV
QPLYGGKVVVLPPPDGTEVHRGEVLFQLDPTEAIADEKDAEAALSSVQAEAMRRRAALAAATATEVNRSARINWAADVPE
KLRKREDAILASELGQLDASLTSLRSQVRQKEGERDHLQDTLDEQASLVDTLQQRVAMRSTLVGENAGPVASVIDATETL
KTQRTQFAIQKGQLADAVAGIDVLKAEIEKTRSTFISDQTERLGDAERQAEDLEERLAKTRAELAQMTVRSPIDGVVQTS
VISTEGQVVTAGEEVLRVVPAGAELELEVYVPNRDIGFIHVGQPAVVKLDAFPFTRYGTVPATITKIATDAIPEPDAERR
EEDAAAAPQTSLFAGAERIQNLVFAVTLKLEQNAVRANGADIPLSPGMSATAEMRTGTRRILGYVFSPLVEVASDAMKER

Specific function: Involved in the transport of the hemolysin/leukotoxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51692; Mature: 51561

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAARTIAAPPPPTRSRSDNQFLAPALEVLETPPSPVGTALLLIICLLATIALTWAYVG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RIDIIATAQGKIQPVGRVKVVQPLYGGKVVVLPPPDGTEVHRGEVLFQLDPTEAIADEKD
CEEEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCHHHHCCCHH
AEAALSSVQAEAMRRRAALAAATATEVNRSARINWAADVPEKLRKREDAILASELGQLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
SLTSLRSQVRQKEGERDHLQDTLDEQASLVDTLQQRVAMRSTLVGENAGPVASVIDATET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LKTQRTQFAIQKGQLADAVAGIDVLKAEIEKTRSTFISDQTERLGDAERQAEDLEERLAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
TRAELAQMTVRSPIDGVVQTSVISTEGQVVTAGEEVLRVVPAGAELELEVYVPNRDIGFI
HHHHHHHHHHHCCHHHHHHHHEECCCCCEEECHHHHHHHCCCCCEEEEEEEECCCCEEEE
HVGQPAVVKLDAFPFTRYGTVPATITKIATDAIPEPDAERREEDAAAAPQTSLFAGAERI
ECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
QNLVFAVTLKLEQNAVRANGADIPLSPGMSATAEMRTGTRRILGYVFSPLVEVASDAMKE
HHHHHHEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure 
TVAARTIAAPPPPTRSRSDNQFLAPALEVLETPPSPVGTALLLIICLLATIALTWAYVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RIDIIATAQGKIQPVGRVKVVQPLYGGKVVVLPPPDGTEVHRGEVLFQLDPTEAIADEKD
CEEEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCEEEEECCHHHHCCCHH
AEAALSSVQAEAMRRRAALAAATATEVNRSARINWAADVPEKLRKREDAILASELGQLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
SLTSLRSQVRQKEGERDHLQDTLDEQASLVDTLQQRVAMRSTLVGENAGPVASVIDATET
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LKTQRTQFAIQKGQLADAVAGIDVLKAEIEKTRSTFISDQTERLGDAERQAEDLEERLAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
TRAELAQMTVRSPIDGVVQTSVISTEGQVVTAGEEVLRVVPAGAELELEVYVPNRDIGFI
HHHHHHHHHHHCCHHHHHHHHEECCCCCEEECHHHHHHHCCCCCEEEEEEEECCCCEEEE
HVGQPAVVKLDAFPFTRYGTVPATITKIATDAIPEPDAERREEDAAAAPQTSLFAGAERI
ECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
QNLVFAVTLKLEQNAVRANGADIPLSPGMSATAEMRTGTRRILGYVFSPLVEVASDAMKE
HHHHHHEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2402458; 1961107 [H]