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The map label for this gene is htpG [H]

Identifier: 190894939

GI number: 190894939

Start: 657522

End: 659408

Strand: Reverse

Name: htpG [H]

Synonym: RHECIAT_PC0000604

Alternate gene names: 190894939

Gene position: 659408-657522 (Counterclockwise)

Preceding gene: 190894940

Following gene: 190894935

Centisome position: 60.41

GC content: 58.61

Gene sequence:

>1887_bases
ATGACGACAAGTGTCGAACAGAATGTCGAAAGCCACGTCTTCGAGGCCGATGTCGCCCGCCTTCTGCATATGATGGTCCA
CTCCGTCTACTCGGACAAGGACGTCTTTCTGCGCGAATTGATCTCGAATGCAGCCGATGCCTGCGAGAAGCTTCGCTATG
AGGCGATCGAGGCACCGGCGCTGCTGGGATCAGTTGCCGAGAGCCGTATCACGCTGTCGCTGGACGACGAGAGCCGACAG
CTCGTCGTGGAGGACAACGGCATCGGGATGCAGCGCGACGAAATGATCGAGGCCCTCGGGACGATTGCGAGGTCGGGGAC
CCGGGCTTTCATGGATCGCATAGCAGCGAGCAAAGCCGGTGAAGGCGCTCAACTGATCGGCCAATTCGGCGTCGGCTTCT
ATTCCTGCTTCATGGTCGCGGATCGGGTCGACGTGATCTCCCGCCGCGCCGGCTCGGAGGAAGCCGCGAAGTGGTCCTCG
GACGGCAAGGGGAGTTACAGCGTCGCTGCGGTAAATCTTGCCGAGGCGCCAGAGCGCGGCACGCGCATTGTCCTGCATCT
GATGGAGGATGCGAAGAAATACACTTCCAGGTGGACTGTCGAGCGGATCGTCAAAGAACAATCCGGCCATGTTCCCGTCG
CAATCCGGCTTATTGAAAAGCCGGGCAGCGAACCGGTTGAGATTACCGACGGCACCGCGCTCTGGACAAAATCGAAGAGC
GAAGTCAGCAAGGAAGAATATACCGACTTCTACCGCGGCGTGTCCGGTCAATACGATGAACCGGTCCTTACCGTGCACTT
CCGTGCCGAAGGCCGGCATGAATACACGGCTCTCGCCTTTGTGCCTGGAACACAGCCGTTCGACATGTTTGACCCGGATC
GCAAGGGGAGGATGAAGCTTTACGTCAAGCGCGTCTTCATCACCGACGACGCGGAACTGATGCCGAGATATCTGCGCTTT
GTCAGGGGCTTGGTCGATACGGCTGATCTGCCGCTCAATGTTTCTCGCGAAATGATCCAGGAAAGCTCGATCCTGGCGGC
GATCCGCAAAGGCGTCACGAACCGGGTCATCACCGCCATCGAGAAAATGGCCGATAGCGAGCCGGACACCTACCTCAAGT
TCTGGGAGAACTTCGGAGCTGTCTTGAAGGAAGGCATTTACGAAGACTACGAGCGGCGCACGCAACTGATGGCGCTTGCG
CGCTTTCGTACCTCGACCTTGTCCGAAGGCTACCGTTCCTTGGCTGAATACGTCAAAGACGCGAAAGAAGGCCAAAATGC
CATCTACTATCTTGCGGGTAGCAGCCTCGACCAGTTGAAGGCATCGCCACAGCTGGAAGGCTTTCGGGCGCGCGGCATCG
AAGTCCTGCTGTTGACCGACTCGGTCGACAGCTTCTGGGCGGTGAATGCACCGGAGTTCGAAGGCAAGGCATTCAAGTCC
ATCACGCAAGGAGCTGCGGATCTTGCAGGCTTTCCAACCACCGATGGTCAAACACCGCAGGAACTGGATGGCGCCGGCCT
GGCGATCTTCATCGGCTTCGCCAAGGAGAAACTGGCCGGTCAAGTCTCCGATGTCCGTGCATCCGACCGGCTGACGGAGA
GCGCAGTCTGCCTCGTTGCGCCGGAGGATGGTTATGACAGGCAGATGGAAAAGATTCTGCAGAATGCAGGTCGTCTCCAA
GGCGCCGCCAAGCCAATTCTGGAAATCAACCTGGCCCATCCTTTGGTCAGAGCTATCGCAGCGGTCGAGAACGATGCCTC
CTATCAGGAGGACGCAACATTCTTGCTGCTCGACCAAGCGCGCATTCTGGACGGCGACCGGCCGGAAGATCCCCGAAAAT
TCGCGGAGCGGCTGGCGAGAGTCTTCCAGAGGTCTGTCCCTTCCTAA

Upstream 100 bases:

>100_bases
AGCGTGCTTCGCGCTCGCATCTGCTTTCAGCCCTTGAATTTTGCGCCCGGTTTCGCCAATTGATCGGCGGAAAAATCCGT
ATCTTTCGGGGAAACCAAGC

Downstream 100 bases:

>100_bases
GCTGGGCTTCTTCAGCGCCCAAGCCGGTAACAGGCGTCGGCTTGTCGCGGGTGTCGCCATGAGTTTCCTGGCGGCATCTG
CAGCCGACACTACACGGTGG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTTSVEQNVESHVFEADVARLLHMMVHSVYSDKDVFLRELISNAADACEKLRYEAIEAPALLGSVAESRITLSLDDESRQ
LVVEDNGIGMQRDEMIEALGTIARSGTRAFMDRIAASKAGEGAQLIGQFGVGFYSCFMVADRVDVISRRAGSEEAAKWSS
DGKGSYSVAAVNLAEAPERGTRIVLHLMEDAKKYTSRWTVERIVKEQSGHVPVAIRLIEKPGSEPVEITDGTALWTKSKS
EVSKEEYTDFYRGVSGQYDEPVLTVHFRAEGRHEYTALAFVPGTQPFDMFDPDRKGRMKLYVKRVFITDDAELMPRYLRF
VRGLVDTADLPLNVSREMIQESSILAAIRKGVTNRVITAIEKMADSEPDTYLKFWENFGAVLKEGIYEDYERRTQLMALA
RFRTSTLSEGYRSLAEYVKDAKEGQNAIYYLAGSSLDQLKASPQLEGFRARGIEVLLLTDSVDSFWAVNAPEFEGKAFKS
ITQGAADLAGFPTTDGQTPQELDGAGLAIFIGFAKEKLAGQVSDVRASDRLTESAVCLVAPEDGYDRQMEKILQNAGRLQ
GAAKPILEINLAHPLVRAIAAVENDASYQEDATFLLLDQARILDGDRPEDPRKFAERLARVFQRSVPS

Sequences:

>Translated_628_residues
MTTSVEQNVESHVFEADVARLLHMMVHSVYSDKDVFLRELISNAADACEKLRYEAIEAPALLGSVAESRITLSLDDESRQ
LVVEDNGIGMQRDEMIEALGTIARSGTRAFMDRIAASKAGEGAQLIGQFGVGFYSCFMVADRVDVISRRAGSEEAAKWSS
DGKGSYSVAAVNLAEAPERGTRIVLHLMEDAKKYTSRWTVERIVKEQSGHVPVAIRLIEKPGSEPVEITDGTALWTKSKS
EVSKEEYTDFYRGVSGQYDEPVLTVHFRAEGRHEYTALAFVPGTQPFDMFDPDRKGRMKLYVKRVFITDDAELMPRYLRF
VRGLVDTADLPLNVSREMIQESSILAAIRKGVTNRVITAIEKMADSEPDTYLKFWENFGAVLKEGIYEDYERRTQLMALA
RFRTSTLSEGYRSLAEYVKDAKEGQNAIYYLAGSSLDQLKASPQLEGFRARGIEVLLLTDSVDSFWAVNAPEFEGKAFKS
ITQGAADLAGFPTTDGQTPQELDGAGLAIFIGFAKEKLAGQVSDVRASDRLTESAVCLVAPEDGYDRQMEKILQNAGRLQ
GAAKPILEINLAHPLVRAIAAVENDASYQEDATFLLLDQARILDGDRPEDPRKFAERLARVFQRSVPS
>Mature_627_residues
TTSVEQNVESHVFEADVARLLHMMVHSVYSDKDVFLRELISNAADACEKLRYEAIEAPALLGSVAESRITLSLDDESRQL
VVEDNGIGMQRDEMIEALGTIARSGTRAFMDRIAASKAGEGAQLIGQFGVGFYSCFMVADRVDVISRRAGSEEAAKWSSD
GKGSYSVAAVNLAEAPERGTRIVLHLMEDAKKYTSRWTVERIVKEQSGHVPVAIRLIEKPGSEPVEITDGTALWTKSKSE
VSKEEYTDFYRGVSGQYDEPVLTVHFRAEGRHEYTALAFVPGTQPFDMFDPDRKGRMKLYVKRVFITDDAELMPRYLRFV
RGLVDTADLPLNVSREMIQESSILAAIRKGVTNRVITAIEKMADSEPDTYLKFWENFGAVLKEGIYEDYERRTQLMALAR
FRTSTLSEGYRSLAEYVKDAKEGQNAIYYLAGSSLDQLKASPQLEGFRARGIEVLLLTDSVDSFWAVNAPEFEGKAFKSI
TQGAADLAGFPTTDGQTPQELDGAGLAIFIGFAKEKLAGQVSDVRASDRLTESAVCLVAPEDGYDRQMEKILQNAGRLQG
AAKPILEINLAHPLVRAIAAVENDASYQEDATFLLLDQARILDGDRPEDPRKFAERLARVFQRSVPS

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=678, Percent_Identity=34.8082595870207, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI155722983, Length=641, Percent_Identity=31.201248049922, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI154146191, Length=409, Percent_Identity=34.718826405868, Blast_Score=243, Evalue=5e-64,
Organism=Homo sapiens, GI153792590, Length=409, Percent_Identity=34.718826405868, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI4507677, Length=418, Percent_Identity=34.4497607655502, Blast_Score=239, Evalue=8e-63,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=42.24, Blast_Score=487, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=35.1713859910581, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17542208, Length=674, Percent_Identity=33.0860534124629, Blast_Score=351, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI115535205, Length=595, Percent_Identity=31.4285714285714, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI115535167, Length=431, Percent_Identity=34.338747099768, Blast_Score=236, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6323840, Length=672, Percent_Identity=33.1845238095238, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6325016, Length=676, Percent_Identity=32.8402366863905, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17647529, Length=686, Percent_Identity=33.3819241982507, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI21357739, Length=688, Percent_Identity=31.8313953488372, Blast_Score=341, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24586016, Length=641, Percent_Identity=32.7613104524181, Blast_Score=321, Evalue=1e-87,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69659; Mature: 69528

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSVEQNVESHVFEADVARLLHMMVHSVYSDKDVFLRELISNAADACEKLRYEAIEAPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGSVAESRITLSLDDESRQLVVEDNGIGMQRDEMIEALGTIARSGTRAFMDRIAASKAG
HHHHHHHCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EGAQLIGQFGVGFYSCFMVADRVDVISRRAGSEEAAKWSSDGKGSYSVAAVNLAEAPERG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEHHHCCCCC
TRIVLHLMEDAKKYTSRWTVERIVKEQSGHVPVAIRLIEKPGSEPVEITDGTALWTKSKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCEEEECCHH
EVSKEEYTDFYRGVSGQYDEPVLTVHFRAEGRHEYTALAFVPGTQPFDMFDPDRKGRMKL
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
YVKRVFITDDAELMPRYLRFVRGLVDTADLPLNVSREMIQESSILAAIRKGVTNRVITAI
EEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMADSEPDTYLKFWENFGAVLKEGIYEDYERRTQLMALARFRTSTLSEGYRSLAEYVKD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEGQNAIYYLAGSSLDQLKASPQLEGFRARGIEVLLLTDSVDSFWAVNAPEFEGKAFKS
HHCCCCEEEEEECCCHHHHCCCCCCCCHHCCCEEEEEEECCCCCCEECCCCCCCCHHHHH
ITQGAADLAGFPTTDGQTPQELDGAGLAIFIGFAKEKLAGQVSDVRASDRLTESAVCLVA
HHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHCHHHHHHHHHCCCCCEEEEEE
PEDGYDRQMEKILQNAGRLQGAAKPILEINLAHPLVRAIAAVENDASYQEDATFLLLDQA
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEEEEECH
RILDGDRPEDPRKFAERLARVFQRSVPS
HHCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTSVEQNVESHVFEADVARLLHMMVHSVYSDKDVFLRELISNAADACEKLRYEAIEAPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGSVAESRITLSLDDESRQLVVEDNGIGMQRDEMIEALGTIARSGTRAFMDRIAASKAG
HHHHHHHCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
EGAQLIGQFGVGFYSCFMVADRVDVISRRAGSEEAAKWSSDGKGSYSVAAVNLAEAPERG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEHHHCCCCC
TRIVLHLMEDAKKYTSRWTVERIVKEQSGHVPVAIRLIEKPGSEPVEITDGTALWTKSKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCEEEECCHH
EVSKEEYTDFYRGVSGQYDEPVLTVHFRAEGRHEYTALAFVPGTQPFDMFDPDRKGRMKL
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
YVKRVFITDDAELMPRYLRFVRGLVDTADLPLNVSREMIQESSILAAIRKGVTNRVITAI
EEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMADSEPDTYLKFWENFGAVLKEGIYEDYERRTQLMALARFRTSTLSEGYRSLAEYVKD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEGQNAIYYLAGSSLDQLKASPQLEGFRARGIEVLLLTDSVDSFWAVNAPEFEGKAFKS
HHCCCCEEEEEECCCHHHHCCCCCCCCHHCCCEEEEEEECCCCCCEECCCCCCCCHHHHH
ITQGAADLAGFPTTDGQTPQELDGAGLAIFIGFAKEKLAGQVSDVRASDRLTESAVCLVA
HHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHCHHHHHHHHHCCCCCEEEEEE
PEDGYDRQMEKILQNAGRLQGAAKPILEINLAHPLVRAIAAVENDASYQEDATFLLLDQA
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEEEEECH
RILDGDRPEDPRKFAERLARVFQRSVPS
HHCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA