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The map label for this gene is etfAc [H]

Identifier: 190894921

GI number: 190894921

Start: 638666

End: 639595

Strand: Reverse

Name: etfAc [H]

Synonym: RHECIAT_PC0000586

Alternate gene names: 190894921

Gene position: 639595-638666 (Counterclockwise)

Preceding gene: 190894922

Following gene: 190894920

Centisome position: 58.6

GC content: 65.91

Gene sequence:

>930_bases
ATGACCATTCTTCTTCTGGCCGACCATGACGGCCATCACCTCTCCGACCAGACCGCCAAGGCGCTGACGGCAGCAAGCCA
GATCGGCGCCGACGTGCACATCCTCGTCGCCGGCAAGGCCGCCAGGGCAGCGGCCGATCAGGCCGCCAAACTCTCTGGCG
TCTCCAAGGTGCTGCTGGCCGAAAGCGATGCGCTTGCCAATAATCTCGCCGAGCCGCTGGCCGATCTGATCGTCTCGCTG
GCCGGCTCCTATGACACGATCCTGTCTGCCGCCACCTCGGTCGGCAAGACCGTGCTGCCGCGCGTCGCCGCCCTGCTCGA
TGTCGCCCAGGTCTCGGAGATCATCGAGGTCGTCAGCCCCGATACCTTCAAGCGGCCGATCTATGCCGGCAACGCCATCC
AGACGGTGCAGGCAAGCGATGCGAAGAAGGTGATCACCGTGCGCACCGCCTCGTTTGCTTCGGCACCGACAGGCGGCTCG
GCAACGGTCGAGGCGATCGCAGCGGTCTCCGATCCGGGTCTGTCGCGCTTCGTCGCCGATGCGCTGTCGGCCTCCGACCG
CCCGGAACTGACCTCGGCCAAGATCATCATCTCCGGCGGCCGGGCGCTTGGTTCGGCGGAAAAGTTCAAGGAGGTCATCC
TGCCGGTTGCCGACAAGCTTGGGGCTGCCGTCGGCGCCAGCCGGGCGGCCGTCGATGCCGGTTATGCCCCGAACGACTGG
CAGGTCGGCCAGACCGGCAAGGTGGTGGCGCCCGATCTCTATATCGCCGCCGGCATCTCCGGCGCCATCCAGCATCTGGC
CGGCATGAAGGATTCGAAGGTGATCGTCGCCATCAACAAGGACGAGGAGGCGCCGATCTTCCAGGTCGCCGACTACGGCC
TCGTCGCCGATCTGTTCGACGCCCTGCCGGAATTGCAGAAGGCGCTTTAA

Upstream 100 bases:

>100_bases
CGCAAGGCCGGCGTCAAGGTCAAGTCGGTCGCCGAACTGGTCGACAGGCTGAAGAACGAAGCCGGCGTGCTGTAATCGGG
TTGGAACAGGAGCAATTATC

Downstream 100 bases:

>100_bases
CGGGGAGACCGAACGTGGCGCGCATGGCGGGACGTCCAATCAGGCCCGGTGCTGACCTTCTCCTCAACGATGAGGAAAAG
CCGGCCTATATAAGACTGCA

Product: electron-transport flavoprotein, subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTILLLADHDGHHLSDQTAKALTAASQIGADVHILVAGKAARAAADQAAKLSGVSKVLLAESDALANNLAEPLADLIVSL
AGSYDTILSAATSVGKTVLPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQASDAKKVITVRTASFASAPTGGS
ATVEAIAAVSDPGLSRFVADALSASDRPELTSAKIIISGGRALGSAEKFKEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDALPELQKAL

Sequences:

>Translated_309_residues
MTILLLADHDGHHLSDQTAKALTAASQIGADVHILVAGKAARAAADQAAKLSGVSKVLLAESDALANNLAEPLADLIVSL
AGSYDTILSAATSVGKTVLPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQASDAKKVITVRTASFASAPTGGS
ATVEAIAAVSDPGLSRFVADALSASDRPELTSAKIIISGGRALGSAEKFKEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDALPELQKAL
>Mature_308_residues
TILLLADHDGHHLSDQTAKALTAASQIGADVHILVAGKAARAAADQAAKLSGVSKVLLAESDALANNLAEPLADLIVSLA
GSYDTILSAATSVGKTVLPRVAALLDVAQVSEIIEVVSPDTFKRPIYAGNAIQTVQASDAKKVITVRTASFASAPTGGSA
TVEAIAAVSDPGLSRFVADALSASDRPELTSAKIIISGGRALGSAEKFKEVILPVADKLGAAVGASRAAVDAGYAPNDWQ
VGQTGKVVAPDLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFDALPELQKAL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=53.6977491961415, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=56.7272727272727, Blast_Score=292, Evalue=3e-79,
Organism=Escherichia coli, GI1786226, Length=285, Percent_Identity=32.280701754386, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787990, Length=304, Percent_Identity=31.25, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082157, Length=219, Percent_Identity=30.1369863013699, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=54.3408360128617, Blast_Score=313, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=283, Percent_Identity=47.3498233215548, Blast_Score=248, Evalue=8e-67,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=57.0512820512821, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=57.0512820512821, Blast_Score=319, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31435; Mature: 31304

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLLADHDGHHLSDQTAKALTAASQIGADVHILVAGKAARAAADQAAKLSGVSKVLLA
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ESDALANNLAEPLADLIVSLAGSYDTILSAATSVGKTVLPRVAALLDVAQVSEIIEVVSP
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFKRPIYAGNAIQTVQASDAKKVITVRTASFASAPTGGSATVEAIAAVSDPGLSRFVAD
CCCCCCEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
ALSASDRPELTSAKIIISGGRALGSAEKFKEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFD
CCCCCCCEECCCHHEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
ALPELQKAL
HHHHHHHCC
>Mature Secondary Structure 
TILLLADHDGHHLSDQTAKALTAASQIGADVHILVAGKAARAAADQAAKLSGVSKVLLA
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ESDALANNLAEPLADLIVSLAGSYDTILSAATSVGKTVLPRVAALLDVAQVSEIIEVVSP
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFKRPIYAGNAIQTVQASDAKKVITVRTASFASAPTGGSATVEAIAAVSDPGLSRFVAD
CCCCCCEECCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
ALSASDRPELTSAKIIISGGRALGSAEKFKEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFD
CCCCCCCEECCCHHEECCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHH
ALPELQKAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]