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The map label for this gene is tctD [H]

Identifier: 190894846

GI number: 190894846

Start: 555838

End: 556506

Strand: Reverse

Name: tctD [H]

Synonym: RHECIAT_PC0000511

Alternate gene names: 190894846

Gene position: 556506-555838 (Counterclockwise)

Preceding gene: 190894847

Following gene: 190894845

Centisome position: 50.98

GC content: 60.69

Gene sequence:

>669_bases
ATGCGACTGCTCGTGGTGGAGGACAACAAGGATCTGGCGGCCTGGCTGGGCAAAGCCCTGCGGCAGGCGCAATACGCCAT
CGACATCGCCCATGATGGTGAGGATGCCGAGCATATGCTGAAGGTCGCCGAGTATTCGGCGATGATCCTCGACCTTGCGC
TGCCCAAGCTCGACGGATTGACGCTTTTAAAGCGGCTGAGACAATCCGGCAGCAAACTGCCGGTCATCATCCTGACGGCC
AATGCAAGCCTGGACGGCCGCGTGGCGGGTCTCGACAGCGGCGCCGACGACTATCTCGCCAAGCCCTTCGAAATCGCCGA
GCTCGAAGCCAGGATCCGGGCGGTGGTGCGCCGCGGACAGGACCGCGCATCTTCGGAAATCACGGTTGGAGACTTGCTTT
TTTCCGGTGGGACGCGGCAATTTTTCGTCGCAGGCGAGCCGCTGCAGCTGACGCCGCGGGAATATGCCGTTCTCGAGCAG
CTCGTCATGAAGTTGGGTACCACGGTTTCGAAGACCGCCCTTTCCGAAAGCGTCTTCGGCTTCGACGACGAGGCGGATCC
AAGCGCCATCGAAATCTACATCCACAGGCTGCGAAAGAAGCTCGAGAACAGTTCGGTTCAGATCGCGACACTGCGGGGGC
TCGGCTATCTCCTCAGACATGTCCAGTAG

Upstream 100 bases:

>100_bases
TAGATGTAAGCCTCTCCTGATCAGCTTGAATGTGGGGTGCTCGTCAGCGGCGGCAACGGGTCGCTTCCGCTAGCCCGTCC
GCACGTGCTAAGGGGATCGG

Downstream 100 bases:

>100_bases
CGTCGGCCCCAGAATCGGCGCGACGATCGCGCGGCTCAGCCGGAGCCTGCGCGTGCAGCTGCTTTGCTGGGTGCTGCTGA
CCCTGCTCGGCGCGATCGGT

Product: putative two-component response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGSKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGDLLFSGGTRQFFVAGEPLQLTPREYAVLEQ
LVMKLGTTVSKTALSESVFGFDDEADPSAIEIYIHRLRKKLENSSVQIATLRGLGYLLRHVQ

Sequences:

>Translated_222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGSKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGDLLFSGGTRQFFVAGEPLQLTPREYAVLEQ
LVMKLGTTVSKTALSESVFGFDDEADPSAIEIYIHRLRKKLENSSVQIATLRGLGYLLRHVQ
>Mature_222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGSKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGDLLFSGGTRQFFVAGEPLQLTPREYAVLEQ
LVMKLGTTVSKTALSESVFGFDDEADPSAIEIYIHRLRKKLENSSVQIATLRGLGYLLRHVQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=44.0366972477064, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=39.4495412844037, Blast_Score=163, Evalue=7e-42,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=35.3211009174312, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.6828193832599, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.0909090909091, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=31.3636363636364, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786911, Length=174, Percent_Identity=35.0574712643678, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=28.125, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.1061946902655, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=88, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=25.1082251082251, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=30, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24416; Mature: 24416

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGL
CEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
TLLKRLRQSGSKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHCCC
DRASSEITVGDLLFSGGTRQFFVAGEPLQLTPREYAVLEQLVMKLGTTVSKTALSESVFG
CCCCCCEEEHHEEECCCCEEEEEECCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
FDDEADPSAIEIYIHRLRKKLENSSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCC
>Mature Secondary Structure
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGL
CEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
TLLKRLRQSGSKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHCCC
DRASSEITVGDLLFSGGTRQFFVAGEPLQLTPREYAVLEQLVMKLGTTVSKTALSESVFG
CCCCCCEEEHHEEECCCCEEEEEECCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
FDDEADPSAIEIYIHRLRKKLENSSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]