Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 190894845

GI number: 190894845

Start: 554448

End: 555785

Strand: Reverse

Name: qseC [H]

Synonym: RHECIAT_PC0000510

Alternate gene names: 190894845

Gene position: 555785-554448 (Counterclockwise)

Preceding gene: 190894846

Following gene: 190894840

Centisome position: 50.92

GC content: 65.62

Gene sequence:

>1338_bases
GTGCAGCTGCTTTGCTGGGTGCTGCTGACCCTGCTCGGCGCGATCGGTTTCAATCTTTACGACAGTTTCTGGACGGCGGA
TGCCACGGCAAAGCTGGTGACGGATCGAACGCTTCTGGCCTCGGCCCGCGTTATCGCCGAAGCCGTCCGTGTCGATGAAG
GCGGCAATGTCCAGGTGGACGTGCCGCCGGCTGCGCTCGAGATGTTCGATACCGGCTTCGGCGACCGGGTCTTTTACCAG
GTCATCACCGTCTGGGGCAGTCTGGTCAGCGGCTTTCCCGACCTGCCGCTGCCGGCCAGCCAGCGGACCGGCGAGGATCG
CGCCTTTCACGGCGCTGACGTGCGCGTTCTGATGATCGACCATCCCGTCGTCGGCCTTTCCGGCGATGGCGCGATCTCCG
TGACCGTCGCCGTTACCCACAACAGCCAGTATGCGATGCGGCGGCAATTGTGGCTCTCGGACTTTTCCAAGCAGTTCGTG
CTCGTCTTCGTCGCAAGTCTGGTGACCATCCTCGGCCTTCAACGGGGCCTGGCGCCGGCTCTGAGACTGCGGGACGCTGT
GCGCCAGCGCGGCCGCAACCGTCTTGATCCCCTGCCGCCCGAAATGGTGCAGAGCGAGCTGCAGCCGCTCGTCCATGCGC
TGAACGACCACATGGAGCGTGTCCAGAGCCAGATGGCGGCGCAGCGACGGTTCGTATCGAACGCCGCGCATCAGCTCAGA
ACGCCACTGGCGCTGATTTCGACGCAGGCAAGTGTGGCGGCGCGCGAAGAGGATGCGGCCCGCCGCGACGAGGCGCTTGC
CGCGCTGCGGACCAGCACGCGGCAGATTTCGCGCCTCGCCAGTCAGCTTCTGACGCTGTCGCGGGCCGAGCCGGGAAGCC
GGCGCCCGCGCAGCGATGCGACCAACCTCAGCAAGGCTGCCCGTGAGATCCTGGAGGCGCATGCCGAAGAGGCGCTCCGG
CGCAACATCGACGTCGGGCTCGAAGCGGACCGACCCGTCATCGTCGAGGGCGACGGCACGATGCTGCGCGAGATGCTGGT
AAACCTCATCGACAACGCCATCCGCTACAGCCAAGCGGACGGACGGGTGACGGTCTCGATCAGGCAGGAGGGCGACAATG
CCGTCGTCACCGTGGAGGACAACGGGCCGGGCATTCCCGTGAGCGAGCGCGACCAAGTATTTGAGCGCTTCTATCGAATC
ATCGGAACCGAAAGCGAGGGAAGTGGTCTCGGGCTTGCCATCGTTCGCGAGGTTGTCGAAGGGGCCGGAGGTTCAGTGTC
GCTGGGTGATGCCGTAGGCGGCGGTCTCGTCGTGACCGTGCGGCTTCCGCTTGCTTGA

Upstream 100 bases:

>100_bases
ATCGCGACACTGCGGGGGCTCGGCTATCTCCTCAGACATGTCCAGTAGCGTCGGCCCCAGAATCGGCGCGACGATCGCGC
GGCTCAGCCGGAGCCTGCGC

Downstream 100 bases:

>100_bases
ACCGGAAACGCATCAAACGAATGAAGGCCGGGCGTCGAGCCCGGCCTTCGCTTCGATCCGCCTTGGGAGGGAGGCCGATC
TGGTTACTGCGTGTCGAGGT

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDTGFGDRVFYQ
VITVWGSLVSGFPDLPLPASQRTGEDRAFHGADVRVLMIDHPVVGLSGDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFV
LVFVASLVTILGLQRGLAPALRLRDAVRQRGRNRLDPLPPEMVQSELQPLVHALNDHMERVQSQMAAQRRFVSNAAHQLR
TPLALISTQASVAAREEDAARRDEALAALRTSTRQISRLASQLLTLSRAEPGSRRPRSDATNLSKAAREILEAHAEEALR
RNIDVGLEADRPVIVEGDGTMLREMLVNLIDNAIRYSQADGRVTVSIRQEGDNAVVTVEDNGPGIPVSERDQVFERFYRI
IGTESEGSGLGLAIVREVVEGAGGSVSLGDAVGGGLVVTVRLPLA

Sequences:

>Translated_445_residues
MQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDTGFGDRVFYQ
VITVWGSLVSGFPDLPLPASQRTGEDRAFHGADVRVLMIDHPVVGLSGDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFV
LVFVASLVTILGLQRGLAPALRLRDAVRQRGRNRLDPLPPEMVQSELQPLVHALNDHMERVQSQMAAQRRFVSNAAHQLR
TPLALISTQASVAAREEDAARRDEALAALRTSTRQISRLASQLLTLSRAEPGSRRPRSDATNLSKAAREILEAHAEEALR
RNIDVGLEADRPVIVEGDGTMLREMLVNLIDNAIRYSQADGRVTVSIRQEGDNAVVTVEDNGPGIPVSERDQVFERFYRI
IGTESEGSGLGLAIVREVVEGAGGSVSLGDAVGGGLVVTVRLPLA
>Mature_445_residues
MQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDTGFGDRVFYQ
VITVWGSLVSGFPDLPLPASQRTGEDRAFHGADVRVLMIDHPVVGLSGDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFV
LVFVASLVTILGLQRGLAPALRLRDAVRQRGRNRLDPLPPEMVQSELQPLVHALNDHMERVQSQMAAQRRFVSNAAHQLR
TPLALISTQASVAAREEDAARRDEALAALRTSTRQISRLASQLLTLSRAEPGSRRPRSDATNLSKAAREILEAHAEEALR
RNIDVGLEADRPVIVEGDGTMLREMLVNLIDNAIRYSQADGRVTVSIRQEGDNAVVTVEDNGPGIPVSERDQVFERFYRI
IGTESEGSGLGLAIVREVVEGAGGSVSLGDAVGGGLVVTVRLPLA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=329, Percent_Identity=32.5227963525836, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786783, Length=339, Percent_Identity=28.6135693215339, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=30.6306306306306, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=27.4725274725275, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=26.3333333333333, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790551, Length=276, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=28.448275862069, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=28.75, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=26.6375545851528, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787374, Length=293, Percent_Identity=27.9863481228669, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790861, Length=301, Percent_Identity=29.2358803986711, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.4678111587983, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=28.1632653061224, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=23.4126984126984, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=298, Percent_Identity=28.5234899328859, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=24.2152466367713, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=305, Percent_Identity=24.9180327868852, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=25.4545454545455, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48292; Mature: 48292

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVD
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VPPAALEMFDTGFGDRVFYQVITVWGSLVSGFPDLPLPASQRTGEDRAFHGADVRVLMID
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
HPVVGLSGDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFVLVFVASLVTILGLQRGLAPA
CCEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLRDAVRQRGRNRLDPLPPEMVQSELQPLVHALNDHMERVQSQMAAQRRFVSNAAHQLR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLALISTQASVAAREEDAARRDEALAALRTSTRQISRLASQLLTLSRAEPGSRRPRSDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TNLSKAAREILEAHAEEALRRNIDVGLEADRPVIVEGDGTMLREMLVNLIDNAIRYSQAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
GRVTVSIRQEGDNAVVTVEDNGPGIPVSERDQVFERFYRIIGTESEGSGLGLAIVREVVE
CEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GAGGSVSLGDAVGGGLVVTVRLPLA
CCCCCEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVD
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VPPAALEMFDTGFGDRVFYQVITVWGSLVSGFPDLPLPASQRTGEDRAFHGADVRVLMID
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
HPVVGLSGDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFVLVFVASLVTILGLQRGLAPA
CCEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLRDAVRQRGRNRLDPLPPEMVQSELQPLVHALNDHMERVQSQMAAQRRFVSNAAHQLR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLALISTQASVAAREEDAARRDEALAALRTSTRQISRLASQLLTLSRAEPGSRRPRSDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TNLSKAAREILEAHAEEALRRNIDVGLEADRPVIVEGDGTMLREMLVNLIDNAIRYSQAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
GRVTVSIRQEGDNAVVTVEDNGPGIPVSERDQVFERFYRIIGTESEGSGLGLAIVREVVE
CEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GAGGSVSLGDAVGGGLVVTVRLPLA
CCCCCEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]