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The map label for this gene is codAc2 [H]

Identifier: 190894547

GI number: 190894547

Start: 209818

End: 211107

Strand: Reverse

Name: codAc2 [H]

Synonym: RHECIAT_PC0000209

Alternate gene names: 190894547

Gene position: 211107-209818 (Counterclockwise)

Preceding gene: 190894548

Following gene: 190894545

Centisome position: 19.34

GC content: 62.17

Gene sequence:

>1290_bases
ATGTTCGATCTAATCGTCAGAAACGCAAATCTCCCCGATGGCCGAACCGGCATCGATATCGGTATCGAGGGCGGCAGGAT
CGTTGCCGTCGAGCGCAATCTGCAGGCGCAGGCGGCAGAGGAAATCGACGCAACCGGCAGGCTGGTCAGCCCGCCTTTCG
TCGATCCGCATTTTCATATGGACGCCACGCTATCGCTCGGGCTGCCGCGGATGAACGTCTCCGGCACGCTGCTCGAAGGC
ATTGCGCTCTGGGGGGAGCTGCGCCCGATCGTGACCAAGGAGGAATTGGTCGACCGCGCACTGCGCTATTGCGATCTCGC
GGTCACGCAAGGCCTGCTTTTCATCCGCAGCCATGTCGATACGAGTGATCCCAGACTGGTGACCGTCGAGGCGATGATCG
AAGTCCGCGAAAGGGTCGCGCCCTATATCGATCTGCAACTGGTCGCCTTTCCCCAGGACGGTTATTACCGCTCGCCGGGG
GCGATCGACGCGCTCAACCGGGCGCTCGATATGGGTGTTGACATCGTCGGTGGCATTCCTCACTTCGAACGGACGATGGG
CGACGGCACGGCGTCGGTCGAGGCGCTCTGCCGCATCGCCGCCGATCGTGGCCTGCCGGTCGATATGCATTGCGATGAAA
CCGACGATCCGCTTTCGCGCCATATCGAGACGCTGGCCGCGCAAACCATCCGCTTCGGCCTGCAGGGACGTGTCGCCGGC
TCGCATCTGACCTCGATGCATTCGATGGACAATTATTATGTTTCCAAGCTCATCCCGCTGATGGCAGAGGCGGAGATCAA
TGTGATCCCCAATCCGCTGATCAACATCATGCTGCAGGGCCGGCACGATACTTATCCGAAACGCCGCGGCATGACCCGGG
TCCGGGAGCTGATGGATGCCGGGCTGAATGTCTCCTTCGGGCACGATTGCGTCATGGATCCGTGGTATTCGATGGGGTCC
GGCGACATGCTGGAGGTCGGCCACATGGCGATCCATGTCGCCCAGATGGCCGGCATCGACGACAAGAAAAGGATCTTCGA
CGCACTGACCGTCAATTCGGCGAAGACGATGGGGCTCACCGGCTACGGCTTGGAAATTGGATGCAATGCGGACCTCGTCA
TCCTCCAGGCGAGCGACACGCTCGAGGCGTTGCGGCTCAAGCCGAACCGGCTGGCGGTGATCCGCCGCGGCAAAGTCGTC
GCCCGCACGGCGCCGCGCATCGGCGAGCTCTTCCTGGACGGGCGTCCGGCCCGGATCGACGGCGGCCTGGACTACATACC
TCGCTATTGA

Upstream 100 bases:

>100_bases
GCTCTTGCCATCATGGCCCGCCGCGCCCGCGTCCCGCAGGCGCTGATGCAGCCCTATCGTCGCGGCGAGCGGTGAAGCCG
CCTTTTCCAAAGAGGTTCCG

Downstream 100 bases:

>100_bases
GAAGTGACGGCGCTGACCATCGTTGAAGGGCAAGGCCCTGCCCGGCTCTGCCTATTCCGCCGCTCGGCGAGCGGTGATGA
TCCACGCCTGCGAGTCGAAC

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFDLIVRNANLPDGRTGIDIGIEGGRIVAVERNLQAQAAEEIDATGRLVSPPFVDPHFHMDATLSLGLPRMNVSGTLLEG
IALWGELRPIVTKEELVDRALRYCDLAVTQGLLFIRSHVDTSDPRLVTVEAMIEVRERVAPYIDLQLVAFPQDGYYRSPG
AIDALNRALDMGVDIVGGIPHFERTMGDGTASVEALCRIAADRGLPVDMHCDETDDPLSRHIETLAAQTIRFGLQGRVAG
SHLTSMHSMDNYYVSKLIPLMAEAEINVIPNPLINIMLQGRHDTYPKRRGMTRVRELMDAGLNVSFGHDCVMDPWYSMGS
GDMLEVGHMAIHVAQMAGIDDKKRIFDALTVNSAKTMGLTGYGLEIGCNADLVILQASDTLEALRLKPNRLAVIRRGKVV
ARTAPRIGELFLDGRPARIDGGLDYIPRY

Sequences:

>Translated_429_residues
MFDLIVRNANLPDGRTGIDIGIEGGRIVAVERNLQAQAAEEIDATGRLVSPPFVDPHFHMDATLSLGLPRMNVSGTLLEG
IALWGELRPIVTKEELVDRALRYCDLAVTQGLLFIRSHVDTSDPRLVTVEAMIEVRERVAPYIDLQLVAFPQDGYYRSPG
AIDALNRALDMGVDIVGGIPHFERTMGDGTASVEALCRIAADRGLPVDMHCDETDDPLSRHIETLAAQTIRFGLQGRVAG
SHLTSMHSMDNYYVSKLIPLMAEAEINVIPNPLINIMLQGRHDTYPKRRGMTRVRELMDAGLNVSFGHDCVMDPWYSMGS
GDMLEVGHMAIHVAQMAGIDDKKRIFDALTVNSAKTMGLTGYGLEIGCNADLVILQASDTLEALRLKPNRLAVIRRGKVV
ARTAPRIGELFLDGRPARIDGGLDYIPRY
>Mature_429_residues
MFDLIVRNANLPDGRTGIDIGIEGGRIVAVERNLQAQAAEEIDATGRLVSPPFVDPHFHMDATLSLGLPRMNVSGTLLEG
IALWGELRPIVTKEELVDRALRYCDLAVTQGLLFIRSHVDTSDPRLVTVEAMIEVRERVAPYIDLQLVAFPQDGYYRSPG
AIDALNRALDMGVDIVGGIPHFERTMGDGTASVEALCRIAADRGLPVDMHCDETDDPLSRHIETLAAQTIRFGLQGRVAG
SHLTSMHSMDNYYVSKLIPLMAEAEINVIPNPLINIMLQGRHDTYPKRRGMTRVRELMDAGLNVSFGHDCVMDPWYSMGS
GDMLEVGHMAIHVAQMAGIDDKKRIFDALTVNSAKTMGLTGYGLEIGCNADLVILQASDTLEALRLKPNRLAVIRRGKVV
ARTAPRIGELFLDGRPARIDGGLDYIPRY

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=416, Percent_Identity=43.2692307692308, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1786517, Length=402, Percent_Identity=25.8706467661692, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47145; Mature: 47145

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLIVRNANLPDGRTGIDIGIEGGRIVAVERNLQAQAAEEIDATGRLVSPPFVDPHFHM
CCEEEEECCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCC
DATLSLGLPRMNVSGTLLEGIALWGELRPIVTKEELVDRALRYCDLAVTQGLLFIRSHVD
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSDPRLVTVEAMIEVRERVAPYIDLQLVAFPQDGYYRSPGAIDALNRALDMGVDIVGGIP
CCCCCEEEHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEECCCC
HFERTMGDGTASVEALCRIAADRGLPVDMHCDETDDPLSRHIETLAAQTIRFGLQGRVAG
HHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
SHLTSMHSMDNYYVSKLIPLMAEAEINVIPNPLINIMLQGRHDTYPKRRGMTRVRELMDA
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHC
GLNVSFGHDCVMDPWYSMGSGDMLEVGHMAIHVAQMAGIDDKKRIFDALTVNSAKTMGLT
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEE
GYGLEIGCNADLVILQASDTLEALRLKPNRLAVIRRGKVVARTAPRIGELFLDGRPARID
ECCEEECCCCCEEEEECCCCHHHHHCCCCEEEEEECCEEEEECCCCHHHHEECCCCCEEC
GGLDYIPRY
CCCCCCCCC
>Mature Secondary Structure
MFDLIVRNANLPDGRTGIDIGIEGGRIVAVERNLQAQAAEEIDATGRLVSPPFVDPHFHM
CCEEEEECCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCC
DATLSLGLPRMNVSGTLLEGIALWGELRPIVTKEELVDRALRYCDLAVTQGLLFIRSHVD
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSDPRLVTVEAMIEVRERVAPYIDLQLVAFPQDGYYRSPGAIDALNRALDMGVDIVGGIP
CCCCCEEEHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEECCCC
HFERTMGDGTASVEALCRIAADRGLPVDMHCDETDDPLSRHIETLAAQTIRFGLQGRVAG
HHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
SHLTSMHSMDNYYVSKLIPLMAEAEINVIPNPLINIMLQGRHDTYPKRRGMTRVRELMDA
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHC
GLNVSFGHDCVMDPWYSMGSGDMLEVGHMAIHVAQMAGIDDKKRIFDALTVNSAKTMGLT
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEE
GYGLEIGCNADLVILQASDTLEALRLKPNRLAVIRRGKVVARTAPRIGELFLDGRPARID
ECCEEECCCCCEEEEECCCCHHHHHCCCCEEEEEECCEEEEECCCCHHHHEECCCCCEEC
GGLDYIPRY
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]